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Low doses of some substances can be beneficial, while high doses can be harmful or toxic.

Polycystic Ovary Syndrome likely starts in childhood and may be genetic and influenced by early hormone exposure.

Modern lifestyles, including poor diet, stress, and long-term use of certain medications, hinder the body's ability to heal from inflammation, leading to chronic diseases.

Hormones, especially androgens, play a big role in acne, but most acne sufferers don't have a hormone disorder. Hormonal treatments, including birth control pills, can be very effective for women whose acne doesn't improve with regular treatments.

Foals with Rhodococcus equi infection often have other health problems that lower their chances of survival.

PDGFA/AKT signaling is important for the growth and maintenance of certain skin fat cells.

Drospirenone is a unique progestin with anti-water retention and potential blood pressure benefits, used in birth control and hormone therapy.

Minoxidil with propranolol and diuretics lowers blood pressure but causes fluid retention and hair growth.

Steroids help hair regrowth, and minoxidil slows post-steroid hair loss, but effects are temporary.

The document concludes that certain genetic mutations and dietary factors are involved in acne development, and treatments like isotretinoin and diet changes can help manage it.

Removing both Atr and Trp53 genes in adult mice causes severe tissue damage and death due to DNA damage.

Androgens can both stimulate and cause hair loss, and understanding their effects is key to treating hair disorders.

The document concludes that accurate diagnosis and personalized treatment are important for skin problems in women with PCOS.

Hormonal treatments, including birth control and antiandrogens, can effectively treat acne in women.

Lichen planus pigmentosus causes dark skin patches and is treated by avoiding triggers and using anti-inflammatory medications.

The conclusion is that early diagnosis and a multi-system treatment approach are crucial for managing PCOS and its associated health risks.

Finasteride improves hair loss in women with hyperandrogenism.

The document concludes that specific itchy skin diseases during pregnancy have varying fetal risks and treatments, including corticosteroids and other medications.

Pregnancy can increase lupus activity, but careful planning and treatment can improve outcomes.

Alpha-hydroxy acids, like glycolic acid, safely improve skin issues and work on all skin types.

Skin changes can help diagnose and manage endocrine disorders like thyroid problems, diabetes, and adrenal gland conditions.

Hormonal treatments can help with acne, especially in women, by lowering androgen levels or blocking their effects.

Blocking the virus's entry into cells by targeting certain pathways could lead to early COVID-19 treatments.

Hormones, especially androgens, play a key role in acne, which can be a symptom of systemic diseases like PCOS and may require targeted treatment.

Chemotherapy often causes skin, nail, and hair side effects, significantly impacting quality of life.

Taking low-dose spironolactone and metformin together works better for PCOS symptoms than either drug alone.

Acne is a chronic disease linked to various systemic conditions and has significant psychological and social effects.

People with diabetes or obesity should manage their conditions carefully as they have a higher risk of severe COVID-19.

Advanced nanocarrier and microneedle drug delivery methods are more effective, safer, and less invasive for treating skin diseases.

The document concludes that alopecia areata is an autoimmune disease without a definitive cure, but treatments like corticosteroids are commonly used.