research Clinical Utility of GnRH Analogues in Female Androgen Excess: Highlighting Diagnostic and Therapeutic Applications
GnRH analogues are effective for diagnosing and treating female androgen excess, offering a non-surgical option.
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research The Case of the Elusive Androgen
The patient's high testosterone was reduced by a medication that suppresses gonadotropin.
research Women With Clinically Significant Hirsutism Always Have Detectable Endocrinological Abnormalities
All women with significant unwanted hair growth have hormonal imbalances, often from polycystic ovary syndrome.
research A Case of Severe Hyperandrogenism, Acanthosis Nigricans, and Overt Diabetes: The Use of Non-Invasive Methods for Diagnosis, Pathogenesis, and Management
Non-invasive imaging helped diagnose a woman's severe hormone imbalance and diabetes, and medication successfully treated her condition.
research The Polycystic Ovary Syndrome: Challenges and Opportunities in Adolescent Medicine
Early treatment of PCOS in teens is crucial to prevent long-term health issues like diabetes and heart disease.
research Women With Clinically Significant Hirsutism Always Have Detectable Endocrinological Abnormalities
Most women with excessive hair growth have a hormonal cause.
research Ehrlichiosis and Demodicosis in Bali Local Dog
The dog with severe hair loss and itching improved after treatment for ehrlichiosis and demodicosis.
research Food Hypersensitivity-Induced Chronic Gastrointestinal Inflammation in a Non-Human Primate Model of Diet-Induced Obesity
A high-fat diet caused severe health problems in female macaques but was reversible with a normal diet, while male macaques reacted differently.
research Disappearance of a Virilizing Adrenal Tumor Following Therapy with Cyproterone Acetate
A woman's adrenal tumor disappeared after treatment with cyproterone acetate.
research A Case of Glucocorticoid Resistance Syndrome
The patient likely has Chrousos syndrome, a rare condition causing insensitivity to glucocorticoids, requiring high-dose dexamethasone treatment.
research Impaired Wound Healing in Transgenic Mice Overexpressing the Activin Antagonist Follistatin in the Epidermis
Overexpressing follistatin in mice delays wound healing and reduces scar size.
research American Association of Clinical Endocrinologists Medical Guidelines for Clinical Practice for the Diagnosis and Treatment of Hyperandrogenic Disorders
The guidelines help doctors diagnose and treat hormone-related disorders in women.
research Improved Health-Span and Lifespan in mtDNA Mutator Mice Treated with the Mitochondrially Targeted Antioxidant SkQ1
SkQ1 antioxidant improved health and lifespan in mice.
research Identification of Anabolic Selective Androgen Receptor Modulators with Reduced Activities in Reproductive Tissues and Sebaceous Glands
Two new compounds were found to build bone and muscle without affecting reproductive organs and skin oil glands.
research Abdominal Obesity as a Predictive Factor of Nonalcoholic Fatty Liver Disease Assessed by Ultrasonography and Transient Elastography in Polycystic Ovary Syndrome and Healthy Women
Belly fat is the main predictor of nonalcoholic fatty liver disease in both women with Polycystic ovary syndrome and healthy women.
research Premature Graying, Balding, And Low Bone Mineral Density In Older Women And Men
Balding men had lower bone density, while balding women had higher hip bone density.
research Childhood-Onset Systemic Lupus Erythematosus with Trisomy X and Increased Risk for Bone Complications: A Case Report
A girl with lupus and trisomy X has a higher risk of bone problems like avascular necrosis and osteoporosis.
research The Impact of Gender Affirming Hormone Therapy on Physical Performance
Gender-affirming hormone therapy improves physical performance in trans men to the level of cisgender men, while in trans women, it increases fat mass and decreases muscle mass, with no advantage in physical performance after 2 years.
research Benefits of Testosterone Replacement and Methods of Substitution
Testosterone replacement therapy helps manage deficiency and has various methods, but requires careful monitoring to avoid side effects.
research Changes in Bone Mineral Density in Women with Early-Onset Androgenetic Alopecia and Their Correlations with Hair-Loss Stages: A Cross-Sectional Study
Women with early-onset baldness should be checked for early bone loss, but bone density doesn't change with baldness severity.
research A Novel Point Mutation in the Ligand-Binding Domain of the Human Glucocorticoid Receptor Causing Generalized Glucocorticoid Resistance: The Importance of the C Terminus in Conferring Transactivational Activity
A new mutation in the human glucocorticoid receptor reduces its function and causes resistance to glucocorticoids.
research Resolution of Paraneoplastic Alopecia Following Surgical Removal of a Pancreatic Carcinoma in a Cat
Removing a cat's pancreatic cancer can temporarily reverse hair loss caused by the disease.
research Treatment of Alopecia Areata With Steroid Solution
The steroid solution can regrow hair but often causes skin issues and doesn't work long-term.
research Hyperandrogenism After Menopause
A postmenopausal woman's increased male hormone levels were successfully treated with surgery.
research Hyperandrogenemia in an Ethnically Heterogeneous Cohort of Midwestern United States Diabetic Pregnancies
Exposure to fatty acids significantly increased androgen levels in female dogs, suggesting a link to conditions like insulin resistance and PCOS.
research First Case of V281+I172N/V281L CYP21A2 Genotype Associated with Congenital Adrenal Hyperplasia: A Case Report from Southern Italy
New genotype linked to non-classical congenital adrenal hyperplasia found in Italian siblings.
research Hair as a Retrospective Calendar of Cortisol Production—Increased Cortisol Incorporation into Hair in the Third Trimester of Pregnancy
Hair cortisol levels can show increased stress during late pregnancy but only for up to six months.
research Evidence-Based and Potential Benefits of Metformin in Polycystic Ovary Syndrome: A Comprehensive Review
Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.
research Alopecia Areata: Pathogenesis And Treatment
No single treatment is consistently effective for alopecia areata, and more research is needed.
research Female Pseudohermaphroditism Caused by a Novel Homozygous Missense Mutation of the GR Gene
A new gene mutation causes female pseudohermaphroditism due to glucocorticoid resistance.