research The JAK/STAT Signaling Pathway: From Bench to Clinic
The JAK/STAT pathway is important in cell processes and disease, and JAK inhibitors are promising for treating related conditions.
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research Caraway, Chinese Chives, and Cassia as Functional Foods Considering Nutrients and Health Benefits
Caraway, Chinese chives, and cassia may improve health and prevent diseases due to their nutrients and medicinal properties.
research Post-Finasteride Syndrome and Post-SSRI Sexual Dysfunction: Two Sides of the Same Coin?
PFS and PSSD are similar conditions with persistent sexual dysfunction after stopping medication.
research Chinese Herbal Medicine, Guilu Erxian Glue, as Alternative Medicine for Adverse Side Effects of Chemotherapy in Doxorubicin-Treated Cell and Mouse Models
Guilu Erxian Glue may help reduce chemotherapy side effects like weight loss and heart stress.
research The Stem Cell Niche in Regenerative Medicine
Targeting and modifying the stem cell niche can improve regenerative therapies.
research Polycystic Ovary Syndrome and Cardiovascular Disease
PCOS increases the risk of heart disease and type 2 diabetes in women.
research Recent Advances in Genome-Editing Technology with CRISPR/Cas9 Variants and Stimuli-Responsive Targeting Approaches within Tumor Cells: A Future Perspective of Cancer Management
New CRISPR/Cas9 variants and nanotechnology-based delivery methods are improving cancer treatment, but choosing the best variant and overcoming certain limitations remain challenges.
research Protein Degradation: Expanding the Toolbox to Restrain Cancer Drug Resistance
Using protein degradation to fight cancer drug resistance shows promise but needs more precise targeting and fewer side effects.
research Anticancer Drugs in Surface Waters
Anticancer drugs are increasingly found in surface waters, and their long-term environmental effects are not well understood, requiring better testing methods.
research Human Exposure to Heavy Metals Over the Last 100 Years
People today have lower levels of arsenic, lead, cadmium, and iron in their hair than people did 100 years ago.
research An Industry-Relevant Metal Mixture, Iron Status, and Reported Attention-Related Behaviors in Italian Adolescents
Exposure to certain metals may worsen attention-related behaviors in adolescents, with stronger effects in females.
research The Multisystem Impact of Long COVID: A Comprehensive Review
Long COVID causes a wide range of long-lasting symptoms that change over time and are hard to diagnose and treat.
research Application of Metal Organic Frameworks-Based Functional Composite Scaffolds in Tissue Engineering
Metal organic frameworks-based scaffolds show promise for tissue repair due to their unique properties.
research Protective Effects of Melatonin Against Metabolic and Reproductive Disturbances in Polycystic Ovary Syndrome in Rats
Melatonin may help treat PCOS symptoms in rats.
research Dermatologic Toxicities Associated with Chronic Gamma-Secretase Inhibitor Treatment for Desmoid Tumor
Most patients experienced mild to moderate skin problems during a trial for a desmoid tumor treatment.
research Wnt Is Back in Drugmakers' Sights, but Is It Druggable?
Drugmakers are optimistic about targeting the Wnt pathway for new treatments despite past challenges.
research Immunopathology and Immunotherapy of Inflammatory Skin Diseases
New targeted immunotherapies are improving treatment for inflammatory skin diseases.
research Effects of In Utero Exposure to D-004, a Lipid Extract from Roystonea Regia Fruits, in the Male Rat: A Comparison with Finasteride
D-004 may be a natural alternative to finasteride for treating enlarged prostate and male baldness.
research Valproic Acid Reduces Hair Loss and Improves Survival in Patients Receiving Temozolomide-Based Radiation Therapy for High-Grade Glioma
Valproic acid helps delay hair loss and increases survival time for high-grade glioma patients undergoing radiation therapy.
research Safety of Common Medications for Treating Dermatology Disorders in Pregnant Women
Some skin medications are safe for pregnant women, but others pose risks or should not be used.
research Infertility Treatment in Polycystic Ovary Syndrome: Lifestyle Interventions, Medications, and Surgery
Lifestyle changes are the first step in treating infertility in PCOS, followed by medications like clomiphene and metformin, and then surgery if needed.
research Hair Growth-Promoting Activity of Hot Water Extract of Thuja Orientalis
Thuja orientalis hot water extract may help hair grow by starting the growth phase and improving hair follicle development.
research Epigenetics of Colorectal Cancer
Colorectal cancer development involves both genetic changes and epigenetic alterations like DNA methylation and microRNA changes.
research Weekly Docetaxel in Minimally Pretreated Cancer Patients: A Dose-Escalation Study Focused on Feasibility and Cumulative Toxicity of Long-Term Administration
Giving docetaxel weekly at 40 mg/m² is manageable and has low toxicity for cancer patients.
research Direct-Acting Vasodilators
Hydralazine and minoxidil are blood pressure medications that relax blood vessels, with potential side effects like rapid heartbeat and fluid retention, and are used for severe or pregnancy-related hypertension.
research Keratin-Based Particles for Protection and Restoration of Hair Properties
Keratin-based particles safely improve hair strength, smoothness, and heat protection.
research Effects of 2-Ethylhexanoic Acid on Reproduction and Postnatal Development in Wistar Rats
2-Ethylhexanoic acid harms fertility and delays development in rats.
research Reply
The document concludes that doctors should monitor children's brain development when treating hemangiomas with interferon alfa and consider stopping the treatment if problems arise, while also exploring drugs that might counteract side effects.
research Semiology of Skin Toxicity Associated with Epidermal Growth Factor Receptor Inhibitors
Skin problems like acne, dry skin, and nail and hair changes are common in patients taking EGFR inhibitors.
research Effect and Mechanism of YH0618 Granule on Chemotherapy-Induced Hair Loss in Patients with Breast Cancer: Study Protocol for a Randomized, Double-Blind, Multi-Center Clinical Trial
The trial will test if YH0618 granule prevents hair loss in breast cancer patients during chemotherapy.