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This article describes the synthesis of novel polyamine-modified minoxidil analogs and conjugates to potentially enhance minoxidil's biological activity, selectivity, and water solubility, but reports no new biological results.

This chapter explores the potential benefits of using easily available herbal ingredients in hair care formulations, suggesting they offer therapeutic benefits with reduced side effects for various hair issues like dandruff and hair fall, especially in sensitive populations.

This review explores the biological applications and pharmacokinetics of decursin, a compound isolated from Angelica gigas, highlighting its potential neuroprotective, anti-inflammatory, and anticancer properties based on in vitro and in vivo studies.

In this systematic review, animal studies showed that cytarabine causes multi-organ toxicities, notably neurotoxicity, linked to oxidative stress and other mechanisms, though study quality raises concerns about reliability and translation to human outcomes.

This review explores the concept of cosmetic toxicity in Ayurveda, focusing on chemical hazards in cosmetics and their management, but provides no new clinical findings.

In this study, candidate compound 39 demonstrated potent androgen receptor antagonism and faster hair-growth efficacy in a mouse model compared to pyrilutamide, while maintaining favorable safety and pharmacokinetic profiles, suggesting potential for topical use in androgenic alopecia.

This article summarizes the essential roles and effects of deficiencies of both fat-soluble and water-soluble vitamins, noting issues ranging from blindness due to vitamin A deficiency to scurvy caused by a lack of vitamin C.

This study found that the RADA-GHK and RADA-KGHK peptide hydrogels improved wound healing and cell growth without cytotoxicity, suggesting potential for use in skin regeneration.

This study found that keratin-based particles were able to recover and enhance the mechanical properties and thermal stability of virgin and overbleached Asian hair, improving its strength and smoothness by around 40%, and demonstrated safety in human skin keratinocytes.

This study introduces MicrobeFDT, a tool that clusters chemically similar compounds and links them to gut microbial enzymes and toxicities, demonstrating its utility by uncovering previously unknown metabolism of the cancer drug altretamine.

This review covers recent developments in materials for in vitro and in vivo stem cell manipulation, highlighting innovative substrate properties but does not report new experimental results.

This review discusses previously reported cases of drug-associated hidradenitis suppurativa linked to various immunomodulating medications but reports no new clinical results.

This review discusses the role of phytochemical nanoparticles in cervical cancer therapy and reports no new clinical results; the authors highlight their potential advantages over conventional chemotherapy.

This study found that oral administration of finasteride to pregnant rats caused dosage-related developmental toxicities, including hypospadias and decreased anogenital distance in male offspring.

This review classifies engineered nanomaterials by composition and application in biomedicine, highlighting diverse uses like regenerative medicine and potential occupational side effects, but reports no new clinical results.

This study found that while zebularine did not significantly accelerate wound healing, it improved the quality of restored skin in mice, suggesting potential for further research into epigenetic inhibitors.

This review paper highlights the development and application of organic and biogenic nanocarriers for delivering bioactives, focusing on eco-friendly and sustainable nanotechnology strategies while addressing challenges like toxicity and paving the way for future innovations in green solution approaches.

In this study, the combination of arsenic toxicity and hypoxia in Arabidopsis thaliana altered root development through stress-specific root growth phenotypes and changes in phosphate starvation response, energy metabolism, and redox signaling.

This study identified the osteopontin-derived peptide, FOL-005, as a potential inhibitor of unwanted human hair growth by promoting catagen development without reducing stem cell numbers or showing toxicity.

This review discusses skin-related toxicities associated with targeted cancer therapies and emphasizes the need for dermatologists to understand and manage these adverse effects, but reports no new experimental results.

This article discusses the development of non-myeloablative stem cell transplants, which may expand the safe treatment range of allogeneic SCT, but presents no new clinical results.

This review highlights that while chitosan-based wound dressings with silver nanoparticles show promise for treating infected wounds due to enhanced antimicrobial activity, further studies are needed to address their in vivo toxicity and evaluate their efficacy in infectious animal models.

In this study, researchers developed a mucoadhesive hydrogel ovule containing retinyl palmitate and curcumin for intravaginal use, showing controlled drug release, selectivity against cancerous HeLa cells, and non-toxicity to healthy cells, which may offer a potential treatment for cervical cancer.

In this study, researchers identified compound 30a as a promising topical androgen receptor antagonist that promoted hair growth in mouse models of androgenetic alopecia without noticeable toxicity, suggesting its potential for treating this hair loss condition.

This review discusses the development of bioactive inorganic particles-based biomaterials for skin tissue engineering and reports no new results; the authors highlight potential future directions for these materials in wound management.

This article explores the historical development and evolution of stereotactic radiosurgery (SRS) and stereotactic body radiation therapy (SBRT), emphasizing advancements in safety and technology, and reports no new clinical results.

This review discusses the immunological basis and development of Janus kinase inhibitors for treating skin diseases and reports no new clinical findings.

This review explores research on nanoformulations for enhancing the topical delivery of herbal medicines, noting potential benefits like improved bioavailability and sustained delivery, and emphasizes the need for safety and toxicity guidelines in developing these novel drug delivery systems.

This study found that CI-1033 caused skin lesions in rats that resemble effects seen in humans receiving EGF receptor inhibitors, suggesting this animal model can help explore the mechanisms behind this cutaneous toxicity.

In this study, the researchers reported that the optimized compound 39 demonstrated potent AR antagonism and favorable pharmacokinetics in a hair-growth mouse model, achieving similar efficacy to pyrilutamide with faster onset and preserved safety, offering promise for next-generation topical AR antagonist development.