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The hair follicle dermal sheath is essential for hair shedding and needs to communicate with the outer root sheath for normal hair growth cycles.

Hair loss patterns differ between males and females due to 5 master regulators and JAK-STAT signaling affects hair growth.

Eating disorders are serious, often undiagnosed conditions requiring early treatment, with anorexia being the most deadly and binge-eating the most treatable.

The book explains the science of tissue repair and regeneration, its medical uses, challenges, and ethical concerns.

Tissue-resident memory T cells can protect against infections and cancer but may also contribute to autoimmune diseases.

Hormones and their receptors, especially androgens, play a key role in hair growth and disorders like baldness.

Mice can grow new hair follicles after skin wounds through a process not involving existing hair stem cells, but requiring more research to understand fully.

High lactate dehydrogenase activity is not necessary for the growth of squamous cell carcinoma.

Skin and hair can regenerate after injury due to changes in gene activity, with potential links to how cancer spreads. Future research should focus on how new hair follicles form and the processes that trigger their creation.

The body's change of testosterone into DHT is not necessary for testosterone's muscle and sexual effects.

Chemotherapy in the first trimester of pregnancy is risky, but in the second and third trimesters, it's generally safe with careful drug selection and timing.

The document concludes that the exact way alcohol causes harm to fetal development is unknown, but it significantly affects nutrient transport to the fetus and a safe level of alcohol during pregnancy is not determined.

The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.

Skin fat helps with body temperature control and has other active roles in health.

Obesity increases the risk of developing polycystic ovary syndrome, and weight loss can improve the condition.

New hormonal contraceptives are safer, have fewer side effects, and offer health benefits for women.

Some parents have a mild form of congenital adrenal hyperplasia without symptoms, and they usually don't need treatment.

Products should be called 'sperm-safe' only after thorough, well-designed tests.

Women with PCOS often have mood disorders and a lower quality of life, and treatment should focus on both physical and mental health.

Future research on ectodysplasin should explore its role in diseases, stem cells, and evolution, and continue developing treatments for genetic disorders like hypohidrotic ectodermal dysplasia.

Certain genetic variations are linked to increased androgen levels in PCOS, but more research is needed to understand these connections fully.

The document concludes that menopause should be seen as a natural part of aging and managed with personalized care and informed choices.

PCOS may start before birth, involves metabolic issues, and can be treated with drugs like metformin and lifestyle changes.

An 81-year-old man's white hair began to regain its original color while he was treated with lenalidomide, suggesting that graying hair might be reversible.

New male hormonal contraceptives show promise but need more research on long-term effects and funding for larger trials.

Genetic counselors should be culturally skilled and aware of transgender patients' unique health risks and needs.

The document concludes that regenerating functional ectodermal organs like teeth and hair is promising for future therapies.

Runx genes are important for stem cell regulation and their roles in aging and disease need more research.

5α-reductase inhibitors help treat disorders caused by DHT and have potential for future therapies.

Family-based treatment is the best outpatient care for stable teens with anorexia, and more research is needed on medication and treatment effectiveness for young people with eating disorders.