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This article discusses a proposed "Darwinian" model of carcinogenesis and emphasizes that cancer prevention involves more than avoiding mutagens, as gene-environment interactions are complex and non-linear.

This study developed 3DEEP, a tissue clearing and spatial transcriptomic method, to map hair follicle development in a single time point from a 12-hour-old mouse, detailing molecular stages, signaling dynamics, and structural changes within developing follicles.

This review discusses factors influencing the earlier onset of puberty, such as obesity and exposure to endocrine-disrupting chemicals, and emphasizes the need for further research and public health policy development.

This article explores the complexity and significance of the hair follicle, emphasizing new insights into its biological roles and the involvement of p53 in follicular regression.

This study concluded that Wnt/β-catenin signaling, through Shh and Bmp pathways, is crucial for determining hair follicle fate in embryonic epidermal development.

In this study, researchers observed that the sequence of maturity markers in normal boys showed specific time lags, with some markers appearing before and others after spermarche.

This study used single-cell RNA sequencing to analyze 26,573 cells from the scapular skin of yaks, identifying 11 major cell types and providing insights into the diversity and morphogenesis of hair follicle cell types through detailed maps of DP cells and dermal fibroblasts.

New mutations in the hairless gene may cause hair loss and affect bone development.

This study found that the expression levels of Siah1 and Siah2 in mice skin vary dynamically during postnatal hair follicle development, suggesting their specific roles in modulating the HIF pathway.

This article reviews the physiological changes underlying normal pubertal milestones and emphasizes the importance of understanding these changes to assess pubertal abnormalities, without reporting new clinical findings.

This study found significant changes in gene and protein expression related to hair follicle development in Rex rabbits' skin during the first 8 weeks of life.

This study identified numerous genes that change expression across the anagen, catagen, and telogen stages of cashmere goat hair follicle development, highlighting key signaling pathways involved.

This review discusses the development, regulation, and aging of the human hair follicle pigmentary system and suggests potential for reversing hair graying by manipulating follicle melanocytes in vitro, but reports no clinical results.

This study found that ocu-miR-205 promotes changes in signaling pathways and shifts in hair follicle phases, affecting Rex rabbit hair density by increasing secondary follicles.

Pax9 is crucial for proper tongue surface development and preventing skin-like changes.

This study found that the prenatal skin development in Red Sokoto goats undergoes significant morphological changes across gestational stages, which may be important for their adaptation and thermoregulation after birth.

This study found that VEGF growth factor plays a significant role in the development of androgenetic alopecia and telogen hair loss in women, more so than KGF, TGF-01, or EGF.

This study found that changes in the expression of the Agouti gene contribute to the pale pigmentation in beach mice, with implications for melanocyte development and localization.

Blocking EGFR in mice causes hair loss and skin changes.

This study found that in a mouse model, alopecia areata was associated with changes in heart structure, biochemistry, and gene expression linked to cardiac hypertrophy after ACTH exposure.

This study reports the development of a novel protocol to purify human TRPV3 ion channels, revealing functional properties and differences in ligand interactions, enabling further structural and functional research.

This study found that early adolescent girls who perceive themselves as undergoing pubertal changes report more intense and variable moods, with hormone activity and perceived pubertal status independently predicting mood fluctuations.

This study observed that distinct subsets of Hoxd genes in murine vibrissae and chicken feather primordia are regulated by different lineage-specific enhancers, indicating evolutionary changes in chromatin topology contribute to transcriptional robustness.

This study evaluated factors influencing hair steroid concentrations in early infancy, finding small effects from birth mode, season, and age-related changes, suggesting hair analysis as promising for assessing long-term endocrine activity.

In this study, researchers found that significant transcriptomic changes occur in the skin of Dezhou donkey foals as they age from newborns to one year old, involving gene expression shifts that may enhance skin barrier function and hair follicle development, while reducing collagen synthesis.

This study in a rat model found that dietary rehabilitation with a high protein diet reversed symptoms of kwashiorkor, suggesting a role for free radicals in its development.

This article discusses how modern lifestyle changes, such as stress and poor diet, contribute to hair loss in younger generations, with hair thinning often leading to alopecia; it emphasizes the need for hair root activation to promote hair growth and prevent loss.

This study found that finasteride treatment in male rats may lead to changes in connexin 43 expression in the testes of their offspring, potentially affecting spermatogenesis.

This study observed that during the postnatal development of gray short-tailed opossums, skin transitions from facilitating gas exchange through a dense capillary network at birth to supporting thermoregulation, with significant changes in skin thickness and structure occurring by 35 days old.

In this study, altering the photoperiod in goats increased hormone concentrations and improved hair follicle development and skin antioxidant capacity, suggesting that short photoperiods may create favorable conditions for cashmere growth.