24 citations
,
December 2012 in “Behavioural Brain Research” This study found that altering Allopregnanolone levels in neonatal rats affects their adult exploratory and anxiety-like behaviors and impairs avoidance learning.
6 citations
,
February 2012 in “American Journal of Animal and Veterinary Sciences” This review summarizes major growth factors that promote hair follicle growth, but it reports no new experimental findings.
4 citations
,
October 2014 in “Journal of Integrative Agriculture” This study identified 417 genes with differential expression at varying stages of cashmere growth in goats, highlighting their potential role in tissue remodeling and cashmere regeneration.
1 citations
,
December 2023 This study explored the complex developmental processes of human hair, emphasizing the intricate interactions required for hair follicle morphogenesis and its implications for drug incorporation and concentration interpretation, particularly in early childhood.
1 citations
,
July 2023 in “Communications biology” In this study, researchers found that deleting Med1, a key epigenetic regulator in dental epithelia, led to hair growth on mouse incisors by altering enhancer landscapes and causing a switch from dental to hair lineage transcription programs.
February 2025 in “BMC Veterinary Research” This study examined proteomic changes in Inner Mongolia cashmere goat skin, finding 631 proteins differentially regulated during hair growth stages; key keratin proteins, crucial for hair follicle development, were localized in secondary hair follicles.
October 2022 in “Medical Clinical Update Journal” This case report describes a 7.5-year-old girl with precocious puberty displaying significant secondary sexual development and advanced bone age, treated monthly with Leuprolide.
April 2026 in “Dermatology and Therapy” This Delphi consensus study provides expert insights into hair aging, aims to enhance diagnostic precision and management of age-related hair changes, and identifies possible new therapeutic targets.
253 citations
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April 2009 in “Journal of Biological Chemistry” This study found that p2y5 functions as a novel LPA receptor involved in the G13-Rho signaling pathway, with implications for human hair growth, and proposes renaming it to LPA6.
152 citations
,
April 2002 in “The journal of investigative dermatology/Journal of investigative dermatology” This study presents evidence that keratitis–ichthyosis–deafness syndrome is caused by a mutation in the connexin 26 gene, expanding the gene's known involvement in various disorders.
88 citations
,
September 2003 in “Clinical endocrinology” This review discusses the diagnosis, management, and hormone treatment of transsexual individuals, and examines the risks and effects of cross-sex hormone therapy without presenting new clinical results.
46 citations
,
May 2018 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that the vitamin D receptor is essential for the self-renewal, migration, and differentiation of epidermal stem cells during skin wound healing in mice.
36 citations
,
May 2017 in “The journal of sexual medicine” In this retrospective study, cyproterone acetate treatment in late-pubertal trans-girls was found to be generally safe and led to mild feminizing effects, with more rapid feminization occurring when combined with estrogens.
19 citations
,
October 2004 in “Best Practice & Research in Clinical Obstetrics & Gynaecology” This review discusses the complexities in diagnosing polycystic ovary syndrome and emphasizes the need for individualized assessment based on each patient's specific symptoms and history, but reports no new results.
12 citations
,
February 1986 in “PubMed” This study found that newborn mice given 6-aminonicotinamide developed skin, intestinal, and central nervous system lesions, offering insights into the mechanisms of pellagra.
10 citations
,
July 2015 in “Clinical and Experimental Dermatology” The authors reported a possible association between the use of etanercept and the development of trichorrhexis nodosa, a hair shaft disorder, in a patient without apparent external causes.
9 citations
,
February 2019 in “BMC cancer” This study found that M30 may protect against cyclophosphamide-induced alopecia in mice by enhancing hair growth and preventing abnormal hair, suggesting its potential as a treatment.
4 citations
,
June 2003 in “Fertility and Sterility” In this pilot study, finasteride increased testosterone/dihydrotestosterone and progesterone/dihydroprogesterone ratios in normal ovulatory women but did not alter ovulation or gonadotropin secretion.
2 citations
,
November 2022 in “Journal of Biochemistry and Molecular Biology” This review discusses how aging affects hair follicle stem cells and their environment, contributing to hair loss, and explores strategies to promote hair regrowth, but reports no new results.
1 citations
,
August 2025 in “Frontiers in Bioengineering and Biotechnology” This study found that a 3D wound model, the 3DWoundSE, showed improved responsiveness to injury and cytotoxic stimuli compared to an intact 3D skin equivalent, offering a reproducible and ethical alternative to animal models for early wound response assessment in dermatological research and drug development.
1 citations
,
January 2023 in “Metabolites” This review discusses the relationship between gut microbiota and polycystic ovarian syndrome (PCOS), including its potential mechanisms and the role of alterations in microbiome composition on PCOS pathophysiology.
1 citations
,
January 2017 in “Springer eBooks” The document explains how hair follicles develop, their structure, and how they grow.
August 2026 in “European Journal of Endocrinology” This study found that individualized GAHT regimens, including microdosing, effectively improved gender congruence and quality of life for non-binary individuals, but some experienced a decrease in bone mineral density.
June 2025 in “Голова и шея.” This study observed changes in the electrical and viscoelastic properties of erythrocytes, as well as hemostatic system activation, in women with alopecia following COVID-19 infection, potentially contributing to alopecia development and informing treatment strategies.
November 2024 in “International Journal of Molecular Sciences” In this review, the authors discuss how hair may protect against scalp skin cancer by enabling IL-17-biased immunosurveillance, while hair loss could permit tumor development by reducing this immune protection.
June 2023 in “Biochimica and biophysica acta. Molecular and cell biology of lipids” In this study, researchers found that knockdown of ABCA5 in primary human hair follicle keratinocytes disrupted cholesterol homeostasis and transportation, suggesting its potential role in hair growth disorders by affecting intracellular cholesterol compartmentalization and LXR-mediated transcriptional activity.
March 2022 in “Experimental Eye Research” This study suggests that in a moderately susceptible mouse population, parental uveitis affects the skin development and alters gene expression profiles related to various pathways in offspring without increasing susceptibility to autoimmune uveitis.
April 2010 in “Cancer Research” This study found that altering CDK4 expression in mice affects the population of keratinocyte stem cells, suggesting a correlation with susceptibility to skin papillomas.
July 2008 in “International journal of psychophysiology” This retrospective study found that cyproterone acetate, both alone and with estrogens, was safe, well tolerated, and induced modest feminizing effects in late-pubertal transgender female adolescents.
November 2007 in “Neuro-chirurgie/Neurochirurgie” This study reported that treatment with cyproterone acetate alone and then with incremental estrogen doses induced mild feminizing effects in late-pubertal trans-girls, with further feminization observed after adding estrogen.