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Scientists have made progress in understanding hair follicle stem cells, identifying specific genes and markers, and suggesting their use in treating hair and skin conditions.

The research identified 12 antioxidant compounds in Polygonum multiflorum roots, suggesting these as quality markers for the plant's processed roots.

RSPO1 mutations in certain patients lead to skin cells that don't develop properly and are more likely to become invasive, increasing the risk of skin cancer.

People with hidradenitis suppurativa often have lower vitamin D levels, weaker hip bones, and altered bone metabolism markers.

Fish oil increased cell growth and macrophages in the skin but didn't affect COX-2 expression.

Certain ESR1 gene variations may affect hormone levels and fat distribution in women with high male hormone levels.

Removing a specific gene in certain skin cells causes hair loss on the body by disrupting normal hair development.

R-spondin2 may help treat hair loss, gene differences could explain baldness, a peptide's regulation is linked to psoriasis, B-defensin gene copies may affect a skin condition's risk and severity, and potential markers and targets for alopecia areata were identified.

Finasteride treatment lowers urine androgen and prostaglandin levels, making them potential markers for effectiveness.

The timing of when the gene Bmal1 is active affects aging and survival, with its absence during development, not adulthood, leading to premature aging.

Acne significantly affects mental health and quality of life, with research suggesting hormonal and genetic factors in its development and emphasizing early treatment to prevent scarring.

The document suggests that clinical trials for PCOS should focus on meaningful primary outcomes like live birth rates, rather than less reliable surrogate markers.

Ionizing radiation damages human hair follicles by stopping cell growth, causing cell death, disrupting color, and increasing stress and damage markers.

A new gene, mrp4, is found in mice and may play a unique role in hair follicle development in tails and ears.

The conclusion is that teeth, hair, and claws have similar stem cell niches, which are important for growth and repair, and more research is needed on their regulation and potential markers.

Over 150 new molecules with biological activities were found in traditional herbal medicines, some with potential for new drug development.

The study found that sweat glands normally suppress immune responses, but this is disrupted in certain skin diseases, possibly contributing to their development.

Low-dose acitretin helps nail psoriasis, stem cells may treat scarring alopecia, Chinese men have lower baldness rates, lateral foldplasty is good for ingrown toenails, hair diameter helps diagnose female baldness, childhood trauma linked to alopecia areata, certain hair-weaving leads to scalp conditions in African American women, and new methods for hair research and understanding hair and sweat gland development were introduced.

Finasteride reduces prostate cancer risk but may increase high-grade tumors; new drugs and better diagnosis are in development, but funding and industry commitment are challenges.

Deleting the CRIF1 gene in mice disrupts skin and hair formation, certain proteins affect hair growth, a new compound may improve skin and hair health, blood cell-derived stem cells can create skin-like structures, and hair follicle stem cells come from embryonic cells needing specific signals for development.

SM04755 may be an effective topical treatment for psoriasis.

Blocking IL-12/IL-23p40 helped reverse severe hair loss in patients.

NFIC helps rat dental cells grow and turn into bone-like cells.

Orobanche rapum extract rejuvenates skin and protects skin bacteria, leading to healthier skin.

A man developed a skin reaction from metronidazole, which improved after stopping the drug and starting steroids.

Two gene variations, rs6493497 and rs7176005, may be linked to female hair loss in Chinese people.

Ruxolitinib effectively regrows hair in most patients with severe hair loss.

Skin aging is due to impaired stem cell mobilization or fewer responsive stem cells.

Adding hyaluronic acid helps create larger artificial hair follicles in the lab.

The hair follicle infundibulum plays a key role in skin health and disease, and understanding it better could lead to new skin disease treatments.