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Female mice with disrupted 5α-reductase 1 had significant metabolic issues, including stress response problems, insulin resistance, liver fat buildup, and obesity.

Substance abuse can cause various skin problems, including marks from injections, sores, premature aging, and increased cancer risk.

Medications for enlarged prostate can cause sexual side effects like reduced libido, erectile dysfunction, and ejaculatory problems.

Genetic mutation and carcinogen treatment are both needed for skin cancer to develop in these specific mice.

Mice with a Gsdma3 gene mutation have thicker skin and longer hair follicle openings due to increased β-catenin levels.

Finasteride helps reduce pain and inflammation in animals.

Children are at risk of health issues from exposure to platinum group elements from car exhausts.

A woman developed severe skin damage after using a blood thinner called low-molecular-weight heparin.

The document concludes that the hCG protocol may help in obesity treatment and could be scientifically justified, but more research is needed.

Glypican-1 is important for blood vessel growth in hair follicles and could help treat hair loss.

Proteoglycans are important for hair growth, and a specific treatment can help reduce hair loss.

Understanding and manipulating epigenetic changes can potentially lead to human organ regeneration therapies, but more research is needed to improve these methods and minimize risks.

Lactobacillus plantarum hydrolysates may help increase hair growth by boosting VEGF production.

Certain spices may help prevent and treat skin cancer, but more human trials are needed.

People with myotonic dystrophy type 1 tend to develop basal cell carcinoma at a younger age but not more frequently than others.

Monkeys with more anxious or inhibited temperaments tend to have less hair loss.

Bioengineered salivary glands in mice can produce saliva when tasting sour or bitter, but have different protein levels and nerve signals compared to natural glands.

Ethanol pretreatment affects drug penetration through skin and hair follicles.

Hair growth is influenced by hormones and goes through different phases; androgens can both promote and inhibit hair growth depending on the body area.

New indole-based compounds, particularly cemtirestat, show promise as dual-function drugs for diabetic complications.

Different types of fibroblasts play various roles in kidney repair and aging, and may affect chronic kidney disease outcomes.

Melatonin given to pregnant rabbits improved their babies' fur quality.

Eating less and exercising more, with personalized diet plans and realistic goals, can lead to weight loss and better health, but more research is needed for long-term success.

The conclusion is that managing cholesterol is important for women, especially during pregnancy, breastfeeding, and with PCOS, and involves regular screening and careful treatment choices.

Skin abnormalities can indicate immunodeficiency due to shared origins with the immune system.

ILK is essential for skin development, pigmentation, and healing.

Stem cell therapies show promise for treating various diseases but face challenges in clinical use and require better monitoring techniques.

N-acetyl-L-cysteine (NAC) can prevent DNA damage and protect cells from harm.

The document concludes that regenerating functional ectodermal organs like teeth and hair is promising for future therapies.

Finasteride can cause lasting sexual dysfunction, depression, and other side effects, needing more research for treatment.