This study describes vitiligo as a chronic disorder where genetic, environmental, and immune factors contribute to skin depigmentation, with associations to other autoimmune diseases and potential links to oxidative stress.
September 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that the PPARγ modulator NAC-GED-0507-Levo may protect hair follicles from chemotherapy-induced damage, potentially offering a strategy to address irreversible hair loss in cancer patients.
September 2016 in “Aktualʹnì pitannâ farmacevtičnoï ì medičnoï nauki ta praktiki” In this study, researchers at Zaporozhye State Medical University developed a 2% minoxidil cream-mask and found it thermally stable during manufacturing, with no chemical interactions between active and base components, signaling potential for effective hair growth stimulation treatments.
September 2016 in “한국임상약학회지” In this study, ibuprofen, menthol, and cetirizine were found to potentially prevent or slow down damage to human dermal fibroblast cells caused by intermittent fever in early alopecia.
21 citations
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May 2022 in “Frontiers in Cell and Developmental Biology” This review covers the structure, development, cycle, and molecular regulation of hair follicles but does not report new results, aiming to offer insights for addressing hair follicle-related diseases.
2 citations
,
December 2011 in “[Thesis]. Manchester, UK: The University of Manchester; 2011.” The study suggests that immune privilege collapse in bulge cells and the involvement of pro-inflammatory cytokine interferon-γ contribute to hair follicle stem cell loss in lichen planopilaris.
1 citations
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November 2020 in “Journal of The American Academy of Dermatology” This study found that oral spironolactone is generally well tolerated and may be effective for treating female-pattern hair loss, with improvements in hair regrowth stability as measured by Sinclair scores.
1 citations
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September 2023 in “Skin Appendage Disorders” This study suggests that chronic burn scars may contribute to erosive pustular dermatosis of the scalp and should be considered in differential diagnoses by clinicians.
September 1998 in “Journal of The European Academy of Dermatology and Venereology” Topical 5α-reductase inhibitor helps counteract hair loss and stabilize it.
May 2017 in “InTech eBooks” This review discusses various types of primary cicatricial alopecias, categorized by the predominant type of inflammatory cells involved, and reports no new clinical results.
11 citations
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January 2010 in “Indian Journal of Dermatology, Venereology and Leprology” Hair transplant and applying 5% minoxidil solution can effectively treat permanent hair loss, but it may change hair direction in some cases.
44 citations
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November 2011 in “The Journal of Dermatology” This review discusses recent advancements in the management and diagnosis of primary cicatricial alopecias but reports no new clinical results; emerging insights suggest sebaceous gland dysfunction may play a role in their etiopathogenesis.
April 2016 in “Proceedings of SPIE” This study found that UV laser-induced fluorescence spectroscopy can effectively differentiate between types of alopecia in patients, showing a high correlation between blood circulation levels and tissue autofluorescence intensity.
28 citations
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August 2018 in “Dermatologic Surgery” This abstract is a listing of affiliations and funding, with no new study or results reported.
14 citations
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July 2015 in “Journal of Cosmetic Dermatology” This study found that, in Japanese patients with androgenic alopecia, sebaceous glands exhibit increased multilobulation which may be significant in the condition's pathology.
8 citations
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May 2013 in “Journal of Investigative Dermatology” This review explores the molecular processes behind hair follicle stem cell activation and suggests new potential targets for designing therapies for various types of alopecia, but it reports no clinical results.
7 citations
,
January 2013 in “Journal of Investigative Dermatology” This study suggests that dietary vitamin A may influence alopecia development and progression, but the mechanisms remain unclear, highlighting the interplay between genetics and nutrition in these hair loss conditions.
5 citations
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July 2013 in “Our Dermatology Online” This study found that lichen planopilaris was the most common variant of cicatricial alopecia among patients, with perifollicular fibrosis being a prevalent histopathological feature.
4 citations
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December 2017 in “American Journal of Dermatopathology” This study found that naked hair shafts significantly increased in cicatricial alopecias compared to non-cicatricial types, suggesting their potential use in diagnosing cicatricial alopecia.
4 citations
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January 2009 in “Indian Journal of Plastic Surgery” This study observed that good surgical outcomes for secondary cicatricial alopecia were achieved in 18 patients, with method selection influenced by the size, location, and shape of alopecia.
3 citations
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June 2025 in “Archives of Dermatological Research” In this review, researchers found that TNF-α, IL-17, and JAK inhibitors show the most promise for stabilizing and resolving scarring alopecias, with IL-23 and Interferon Alpha Receptor 1 inhibitors also providing some benefits in managing these hair loss conditions.
2 citations
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August 2020 in “Journal of Cosmetic Dermatology” This study found that in patients with alopecia areata, serum granulysin levels decreased significantly after treatment with tofacitinib and correlated with reduced disease severity, suggesting serum granulysin as an indicator of immunological activity and response to therapy.
January 2009 in “Indian Journal of Plastic Surgery” This study evaluated surgical methods for treating cicatricial alopecia and found that factors such as size, location, and shape are crucial in deciding the approach, with good outcomes seen in 18 out of 24 patients.
October 2025 in “Dermatology Practical & Conceptual” This review discusses different types of alopecia associated with psoriasis and highlights that hair loss in psoriasis is typically non-scarring and reversible, while also noting the increased risk of alopecia areata in these patients.
37 citations
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May 1999 in “Australasian Journal of Dermatology” This review discusses neutrophil-associated and infiltrative scarring alopecias, as well as promising new treatments, but reports no new clinical results.
27 citations
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September 2008 in “British Journal of Dermatology” This study describes patients with moderate to severe scarring alopecia of the scalp margin and suggests that traction is not the sole cause for this condition, as half of the patients had no history of harsh hairstyling practices.
20 citations
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July 2008 in “Dermatologic Therapy” This review discusses various nonfollicular scalp conditions causing secondary scarring or permanent alopecia and highlights the importance of specific diagnoses and treatments but reports no new results.
1 citations
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July 2018 in “Elsevier eBooks” This review discusses the pathogenesis and clinical features of androgenetic alopecia, highlighting potential links to fibrosing alopecia and suggesting the need for combined therapeutic approaches; it reports no new clinical results.
April 2026 in “Frontiers in Immunology” This study concluded that the CXCL12–CXCR4 signaling pathway significantly contributes to hair loss in androgenetic alopecia and alopecia areata by promoting inflammation and fibrosis, whereas inhibiting this pathway can restore hair growth and follicle health.
June 2022 in “Al-Azhar International Medical Journal /Al-Azhar International Medical Journal” This study found that autologous emulsified fat followed by hair transplantation using FUE was more effective than FUE alone in improving outcomes for patients with cicatricial alopecia after six months.