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Gene mutations can cause problems in male genital development.

Finasteride might affect memory by impacting cholinergic system.

We need to learn more about 5α-reductases and neuroactive steroids to safely make drugs targeting these enzymes.

Finasteride treatment can decrease certain steroids and increase others, possibly leading to depression symptoms in some cases.

Finasteride, when taken daily, lowers dihydrotestosterone levels but doesn't noticeably affect adrenal steroid production, except by blocking the 5 alpha-reductase enzyme.

Enzymes called 5α-reductases have many body functions and need more research to safely use inhibitors.

Taking 1 mg finasteride for a year reduces dihydrotestosterone levels in men with early hair loss, but doesn't change their metabolic state.

Mutations in the NR3C1 gene cause a rare condition that affects hormone signaling and can lead to various symptoms, with dexamethasone as a treatment option.

Ashwagandha root improved symptoms of nonclassic 11-hydroxylase deficiency in an elderly woman.

Finasteride may help reduce impulsivity caused by pramipexole.

Short-term finasteride use in male rats caused anxiety, depression, and memory problems.

Skin produces different hormones depending on body part and sex, and a new method can measure them.

Brain-made chemicals can control nerve cell function differently in various parts of a mouse's brain, which may help us understand neurological conditions.

Heavily hunted wolves have higher stress and reproductive hormone levels.

Hair analysis for stress and reproductive hormones in wildlife needs more research for accuracy across species.

New hair growth corticosterone levels are higher in diabetic mice, indicating long-term stress.

Hair cortisol is a reliable stress indicator in cattle but may not be valid for pigs.

Moving horses to new places can increase their stress levels, as shown by higher stress hormone in their hair.

Allopregnanolone changes gene expression in glioblastoma cells.

The method can measure multiple steroids in human hair to study long-term steroid metabolism, especially in newborns and children.

Gastric bypass surgery improved a woman's hormonal disorder without the need for medication.

High levels of cortisol in hair are linked to a greater risk of brain aneurysm rupture.

Testosterone and its metabolites affect brain functions and could help treat neurological disorders.

The conclusion is that certain physical signs in the body can indicate past acute and chronic stress, which may help in child abuse investigations.

Congenital Adrenal Hyperplasia is a rare inherited disease causing hormone imbalances, affecting growth, fertility, and heart health, diagnosed through blood tests and treated with medication and lifestyle changes.

Some lesser-known causes of PCOS include autoimmune issues, genetic mutations, and changes in the body's microbiome.

Melampus might have cured Proetus' daughters, who possibly had ergotism or Cushing's syndrome, using the herb Helleborus niger, but a mix of factors could have caused their symptoms.

Trilostane may help delay epilepsy development by increasing certain brain chemicals.

Finasteride, a hair loss drug, can cause sexual side effects like erectile dysfunction in 2.1%-3.8% of users, but these usually go away with time or if the drug is stopped. Despite this, its impact on sexual function is minimal for most men.

The document concludes that managing skin conditions during pregnancy is important and requires specialized care.