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Microneedle arrays with nanotechnology show promise for painless drug delivery through the skin but need more research on safety and effectiveness.

The document suggests creating a validated score to diagnose Cushing's Syndrome and considers plasma steroid profiling as a simpler diagnostic method.

The document concludes that correct diagnosis and management of PCOS are important, and more research is needed on its risks and treatments.

Children generally have milder SARS symptoms than adults, with good outcomes and no deaths reported, but long-term effects are unclear.

Azathioprine's effectiveness and safety require careful monitoring and more research, especially regarding its use with corticosteroids and the role of TPMT status in patients.

Skin aging is largely due to differences in stiffness and elasticity between skin layers, leading to wrinkles.

Use finasteride, minoxidil, and follicular unit transplantation for hair loss treatment.

Neuroactive steroids show promise for treating mental and neurological disorders by targeting GABA_A receptors.

Fetal cells could improve skin repair with minimal scarring and are a potential ready-to-use solution for tissue engineering.

The document concludes that computational methods using networks and various data can improve the process of finding new uses for existing drugs.

Injectables can feminize or masculinize a transgender person's face, but more research is needed for best practices.

Lizards can regrow their tails, and studying this process helps understand scar-free healing and limb regeneration.

Blocking the prolactin receptor might help treat various diseases, but more research is needed.

Adrenal disorders can cause lasting brain and behavior issues in children.

Use minoxidil for hair loss treatment, and finasteride for men.

The testosterone patch and gel are both effective, but they have different absorption patterns and effects on hormone levels.

5-alpha-reductase inhibitors can lower prostate cancer risk but may increase high-grade tumors and cause sexual side effects.

Natural molecules like inositols, resveratrol, vitamins, and omega-3 fatty acids may help manage Polycystic Ovary Syndrome (PCOS), but their effects vary and need more exploration.

The document concludes that there is no clear definition of adequate health insurance, and a consistent method to measure underinsurance is needed.

Feed restriction in sheep leads to finer wool fibers but may reduce wool quality.

Researchers created a new mouse model for studying Citrullinemia Type I and similar conditions, showing symptoms and treatment responses like those in humans.

Existing drug dexamethasone may lower death risk in severe COVID-19 cases; more research needed for other drugs.

Minoxidil improves blood flow and vessel flexibility, potentially helping with vascular stiffness.

Many young Italian women have hyperandrogenic disorders like PCOS, which are linked to age, body weight, and insulin resistance.

Custom-designed implants effectively repaired skull damage in most soldiers injured in combat.

ALA-PDT is effective and safe for chronic X-ray dermatitis, providing complete or partial remission.

Bidirectional barbed sutures are effective and can reduce surgery time, with a low infection rate and potential cost savings despite being more expensive.

St. John's wort increases finasteride metabolism, reducing its effectiveness; use caution when combining them.

Pregnancy can cause specific skin conditions that need correct diagnosis and treatment to protect both mother and baby.

Hormone therapy for transgender females increases the risk of blood clots and requires careful dosing, monitoring, and lifelong management.