research Treatment of Cultured Sebocytes with an EGFR Inhibitor Does Not Lead to Significant Upregulation of Inflammatory Biomarkers
Blocking EGFR in skin cells doesn't majorly increase inflammation markers.
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research All Roads Lead to the Nucleus: Integration of Signaling, Transcription Factor-Mediated, and Epigenetic Regulatory Mechanisms in the Control of Skin Development and Regeneration
The nucleus is key in controlling skin growth and repair by coordinating signals, gene regulators, and epigenetic changes.
research Generalized Pustular Toxic Erythema: Pathogenetic Relationship Between Pustule and Epidermal Appendage (Hair Follicle or Sweat Duct)
Pustules in toxic erythema are linked to hair follicles or sweat ducts.
research Clinical Management of Cutaneous Adverse Events in Patients on Targeted Anticancer Therapies and Immunotherapies: A National Consensus Statement by the Spanish Academy of Dermatology and Venereology and the Spanish Society of Medical Oncology
Spanish experts provided guidelines for treating skin side effects in cancer patients on new therapies, stressing early action and teamwork.
research Etiological Role of Ferritin and Vitamin D in Patients with Telogen Effluvium
Low ferritin levels might be linked to telogen effluvium, but vitamin D levels are not.
research Sensitive Skin
Sensitive skin is often caused by nerve fibers and environmental factors, and can be managed with mild skincare and professional advice.
research Temporal Triangular Alopecia: Significance of Trichoscopy in Differential Diagnosis
Trichoscopy is reliable for diagnosing Temporal Triangular Alopecia and can prevent unnecessary biopsies and wrong treatments.
research Treatment of Androgenetic Alopecia Using PRP to Target Dysregulated Mechanisms and Pathways
PRP is effective for treating hair loss, especially with other treatments.
research Potential Therapeutic Uses of Thyroid Hormone
Thyroid hormone may be useful for treating various skin conditions and needs more research.
research Cutaneous Adverse Effects of Targeted Therapies
Targeted cancer therapies often cause serious skin problems that need careful management.
research From Telogen to Exogen: Mechanisms Underlying Formation and Subsequent Loss of the Hair Club Fiber
Hair shedding is an active process that could be targeted to treat hair loss.
research Reply
Dr. Jorizzo questions the long-term benefits of minoxidil and tretinoin, while Dr. Olsen defends their effectiveness and stresses the need for public education on these treatments.
research Chemotaxis in Psoriasis
Psoriasis patients have immune cells that respond more strongly to signals and stimuli due to an intrinsic cellular defect.
research Alopecia Areata: Pathogenesis And Treatment
No single treatment is consistently effective for alopecia areata, and more research is needed.
research Beyond Expectations: The Role of Keratin Intermediate Filament Proteins in Epidermal Integrity
Keratin proteins are crucial for healthy skin, but mutations can cause skin disorders with no effective treatments yet.
research Nosological Profile of Dermatological Diseases in Primary Health Care and Dermatology Secondary Care in Florianópolis (2016–2017)
Primary health care in Florianópolis mostly treated simple skin conditions, while secondary care handled more complex skin diseases.
research Eph/Ephrin Signaling in Epidermal Differentiation and Disease
Eph/ephrin signaling is important for skin cell behavior and could be targeted to treat skin diseases.
research Thyroid Hormone Action on Skin
Thyroid hormone affects skin health, with too little causing rough, pale skin and too much leading to smooth, thin skin, and may also impact wound healing and skin conditions.
research Expression of Mu-Opiate Receptor in Human Epidermis and Keratinocytes
μ-opiate receptors in skin cells may affect skin health and healing.
research Overview Of Popular Cosmeceuticals In Dermatology
Many popular skincare products claim to prevent aging but lack strong evidence to prove their effectiveness and safety.
research Re-Investigating the Basement Membrane Zone of Psoriatic Epidermal Lesions: Is Laminin-511 a New Player in Psoriasis Pathogenesis?
Laminin-511 may contribute to psoriasis by affecting skin cell growth and survival.
research Estrogens and Aging Skin
Estrogen therapy can reduce skin aging but has cancer risks.
research Hormones and the Pilosebaceous Unit
Hormones significantly affect hair and oil gland function in the skin, and more research is needed on skin-related hormone disorders.
research Hair-Cycle Dependent Differential Expression of ADAM 10 and ADAM 12
ADAM 10 and ADAM 12 proteins are involved in different stages of hair growth and could be targets for treating hair disorders.
research Cutaneous Blood Flow: Use of Laser Doppler Velocimetry in Dermatology
Laser Doppler velocimetry is a valuable noninvasive tool for skin blood flow research in dermatology.
research Differential Effects of Melatonin as a Broad Range UV-Damage Preventive Dermato-Endocrine Regulator
Melatonin protects skin against UV damage by regulating various cellular processes.
research Role of FGFR2-Signaling in the Pathogenesis of Acne
Increased FGFR2b signaling, influenced by androgens, plays a role in causing acne.
research GLI2-Specific Transcriptional Activation of the Bone Morphogenetic Protein/Activin Antagonist Follistatin in Human Epidermal Cells
GLI2 increases follistatin production in human skin cells.
research Cutaneous Side-Effects of Beta-Adrenergic Blockers
Beta-blockers can cause rare skin side-effects, which usually improve after stopping the medication.
research Serum Irisin Level in Patients with Acne Vulgaris
Patients with acne vulgaris have lower serum irisin levels.