84 citations,
January 2018 in “Biomaterials Science” Sericin hydrogels heal skin wounds well, regrowing hair and glands with less scarring.
25 citations,
June 2018 in “Journal of The American Academy of Dermatology” Genes linked to fibrosis are more active in people with central centrifugal cicatricial alopecia.
July 2021 in “Plastic and reconstructive surgery. Global open” Verteporfin treatment in mice led to complete skin healing without scarring.
94 citations,
June 2016 in “The FASEB Journal” The Wnt/β-catenin pathway helps tissue regeneration but can also cause fibrosis, and drugs that inhibit this pathway may aid in healing skin and heart tissues.
35 citations,
December 2020 in “International Journal of Molecular Sciences” Mast cells likely promote skin scarring and fibrosis, but their exact role is still unclear.
1 citations,
April 2023 in “Science Advances” High levels of ERK activity are key for tissue regeneration in spiny mice, and activating ERK can potentially redirect scar-forming healing towards regenerative healing in mammals.
31 citations,
August 2015 in “Stem Cells Translational Medicine” Human skin can provide stem cells for tissue repair and regeneration, but there are challenges in obtaining and growing these cells safely.
June 2008 in “British Journal of Dermatology” UK medical students lack dermatology education, liver biopsy patients with risk factors show more fibrosis, and certain fungi resist drugs due to melanin; genetics may influence female hair loss.
June 2008 in “British Journal of Dermatology” Herpes gestationis is linked to certain antigens, atopic eczema affects T cell populations and may be eased by breastfeeding, higher doses of anti-androgen treatment can improve androgenic alopecia, topical minoxidil increases hair thickness, long-term methotrexate therapy can cause liver fibrosis in psoriasis patients, and Lichen Sclerosus et Atrophicus patients aren't at higher risk for autoimmune disorders.
5 citations,
July 2013 in “Our Dermatology Online” Lichen planopilaris is the most common type of scarring hair loss observed, with a variety of symptoms and tissue changes.
141 citations,
August 2017 in “Developmental Dynamics” The document concludes that a better understanding of cell changes during wound healing could improve treatments for chronic wounds and other conditions.
81 citations,
September 2005 in “The American journal of pathology” Activin helps skin growth and healing mainly through stromal cells and affects keratinocytes based on its amount.
9 citations,
January 2010 in “International Journal of Trichology” The study found that the cause of alopecia areata can be identified through tissue analysis, and vertical sections are enough for diagnosis.
2 citations,
June 2012 in “Dermatologica Sinica” Dermoscopy is useful for diagnosing and monitoring discoid lupus erythematosus by showing specific skin patterns.
May 2024 in “Scientific reports” Twist2 is essential for scarless skin healing and hair growth in mouse fetuses.
March 2024 in “Research Square (Research Square)” Twist2 is essential for proper skin healing and hair growth in developing mice.
March 2019 in “Nasza Dermatologia Online” A man had both alopecia areata and lichen planus, which is uncommon.
299 citations,
January 2018 in “Journal of Clinical Investigation” Different types of fibroblasts play various roles in diseases and healing, and more research on them could improve treatments.
277 citations,
July 2011 in “Journal of the Dermatology Nurses’ Association” The skin's layers protect, sense, and regulate the body's internal balance, but can be prone to cancer.
211 citations,
May 2018 in “Trends in cell biology” Different types of skin cells play specific roles in development, healing, and cancer.
126 citations,
April 2006 in “International Journal of Dermatology” The conclusion is that FFA and LPP have similar scalp biopsy features, making them hard to distinguish histologically, and FFA may be a specific kind of scarring hair loss.
57 citations,
January 2003 in “Clinical and experimental dermatology” Postmenopausal frontal fibrosing alopecia is a type of hair loss in postmenopausal women that may stop on its own but has no effective treatment.
49 citations,
August 2007 in “Dermatologic surgery” New treatments for acne scars are safer and more effective because we understand the causes better.
41 citations,
May 2018 in “Nutrition and healthy aging” Skin aging is largely due to differences in stiffness and elasticity between skin layers, leading to wrinkles.
41 citations,
July 2015 in “Clinical and Experimental Dermatology” Psoriasis can cause temporary or permanent hair loss.
39 citations,
March 2009 in “Clinics in plastic surgery” Injection lipolysis effectively reduces small fat deposits and should be done with care and proper patient selection.
38 citations,
October 1988 in “Clinics in Dermatology” Minoxidil can help grow hair and make hair follicles bigger, but it can also cause side effects.
29 citations,
September 2014 in “American Journal of Dermatopathology” Horizontal sections of scalp biopsies are good for diagnosing Central Centrifugal Cicatricial Alopecia and help customize treatment.
19 citations,
February 2017 in “Journal of radiation research” High-dose radiation speeds up aging in skin stem cells.
14 citations,
January 2021 in “Scientific Reports” Using micro skin tissue columns improves skin wound healing and reduces scarring.