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Estrogens help reduce skin aging, and SERMs might offer similar benefits without the risks of hormone therapy.

Hair grows faster in the morning and is more vulnerable to damage from radiation due to the internal clock in hair follicle cells.

Some drugs can cause skin, nail, and hair problems, which are important for healthcare professionals to recognize and report.

Oral retinoids are effective for various skin conditions but have side effects and should not be used during pregnancy.

Survivors of Stevens-Johnson syndrome/toxic epidermal necrolysis need ongoing care for various long-term health problems.

Activating TRPV3 stops human hair growth.

Skin surface lipids are important for skin health and altering them could help prevent aging and treat skin conditions.

The TGM3 gene's promoter region is key for skin and hair cell function and may aid gene therapy.

Recombinant cytokine therapy can cause skin reactions ranging from mild to severe.

Treating psoriasis on the scalp, nails, and skin folds is challenging, often requiring systemic treatments for severe cases, with some success in topical and biologic treatments.

COVID-19 can cause skin issues like rashes and "COVID toes," and people with skin conditions should adjust their treatments if they get the virus.

People with alopecia areata often have other health issues like skin diseases, metabolic syndrome, stomach infections, lupus, anemia, thyroid problems, mental health issues, vitamin D deficiency, and hearing and eye problems.

The document concludes that certain genetic mutations and dietary factors are involved in acne development, and treatments like isotretinoin and diet changes can help manage it.

Eating the right nutrients can improve hair health, but taking extra supplements usually doesn't help unless you have a deficiency.

The sebaceous gland has more roles than just producing sebum and contributing to acne, and new research could lead to better skin disease treatments.

Hormones significantly affect hair and oil gland function in the skin, and more research is needed on skin-related hormone disorders.

Pregnancy can cause skin pigmentation, stretch marks, and changes in hair, nails, and sweat glands, with most resolving after birth.

Improving skin barrier and using antifungal treatments can help manage dandruff.

The document concludes that dandruff and seborrheic dermatitis are linked to inflammation and skin changes, and treating them with specific shampoos can reduce these issues.

Cholesterol sulfate buildup due to a genetic mutation disrupts the skin barrier, leading to the scaling skin seen in X-linked ichthyosis.

Pregnancy can increase lupus activity, but careful planning and treatment can improve outcomes.

Alpha-hydroxy acids, like glycolic acid, safely improve skin issues and work on all skin types.

There may be a connection between Frontal Fibrosing Alopecia and Lichen Planus Pigmentosus, and more research is needed to confirm this.

Treatments for melanin disorders exist, but more effective options needed.

Skin problems in COVID-19 patients are rare and may be due to the body's complex immune response or blood clotting issues.

COVID-19 can cause various skin lesions, which may result from the virus and immune response, and are not directly linked to illness severity.

Lichen Planopilaris and Frontal Fibrosing Alopecia may help us understand hair follicle stem cell disorders and suggest new treatments.

The 308-nm Excimer laser is effective and safe for treating patchy alopecia areata in children.

Hidradenitis suppurativa is caused by genetic factors, inflammation, bacteria, hormones, and lifestyle factors like obesity and smoking.

Spironolactone effectively reduces hair growth in women with hirsutism and is generally well-tolerated.