January 2006 in “Chinese Journal of Aesthetic Medicine” This study found that a new-type artificial xenogenic derma exhibited better biocompatibility and dermal tissue regeneration ability compared to cross-linked acellular dermal matrix in a mouse model.
1 citations
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January 1984
5 citations
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January 2021 in “Wiadomości Lekarskie” This study developed a protocol for acellular dermal matrix manufacturing from pig skin, demonstrating effective removal of cellular components while preserving the collagen scaffold's structural organization through a series of physical and chemical treatments.
193 citations
,
June 1990 in “Journal of Investigative Dermatology” 7 citations
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July 2016 in “Journal of Biomedical Materials Research Part A” This study found that a novel hydrogel scaffold, cGEL, significantly increased melanin production and melanotic gene expression in human melanocytes compared to other graft materials, suggesting its potential as a superior carrier for skin grafting.
August 1993 in “Journal of Dermatological Science” 238 citations
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October 1994 in “Current opinion in genetics & development” This article reviews the role of epidermal proteins and regulatory mechanisms in skin diseases, emphasizing recent insights but reports no new experimental results.
164 citations
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February 2010 in “Journal of Cell Science” This study demonstrates that stem cells from human foreskins, which lack hair follicles, can differentiate into melanocytes and migrate to the epidermis, potentially altering our understanding of pigmentation disorders.
November 2022 in “Journal of Investigative Dermatology” This study demonstrated that hiPSC-derived hair-bearing skin organoids lacked sufficient type VII collagen at the epidermal-dermal junction, indicating a need for further maturation to model certain forms of epidermolysis bullosa effectively.
August 1993 in “Journal of Dermatological Science” 114 citations
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October 1996 in “Dermatologic clinics” This chapter reviews laboratory models used for studying alopecia therapies but provides no new experimental findings.
54 citations
,
January 1984 in “Molecular and Cellular Biochemistry”
1 citations
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January 2010 in “Serbian Journal of Dermatology and Venereology” This article reviews the multifaceted approach required for acne vulgaris treatment, emphasizing individualized combination therapies tailored to clinical severity and patient psychological profiles, but no new results are included.
118 citations
,
January 1992 in “Experientia”
1 citations
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January 2019 in “The International Journal of Lower Extremity Wounds” This study demonstrated in rodent models that artificial dermal template treatment can induce full-thickness skin regrowth including skin epidermis and adnexa without the need for autologous skin grafts.
August 2023 in “Journal of Investigative Dermatology” Skin organoids can regenerate hair by forming specific cell units with certain signals.
April 2024 in “International journal of molecular sciences” This review examined and discussed the role of dermis-derived factors in the regulation of melanogenesis, noting their significance in both normal and abnormal mammalian skin conditions, suggesting an underexplored area of study compared to dermal and epidermal influences.
August 2019 in “Journal of Investigative Dermatology” This study found that tight junctions extend to the most superficial layer of the stratum granulosum in human skin, challenging previous claims of their limited presence in the epidermis.
This study utilized a pigmented human epidermal equivalent model to incorporate melanocytes into the epidermis and found enhanced differentiation potential compared to conventional in vitro systems, reflecting in vivo cellular trajectories and highlighting melanocyte-to-keratinocyte communication pathways.
August 2022 in “Tissue Engineering Part A” This study observed that using ex vivo gene therapy to modify skin cells in a pre-graft model improved dermal-epidermal junction adhesion strength and maintained collagen production over time, suggesting a potential treatment approach for recessive dystrophic epidermolysis bullosa skin wounds.
February 2001 in “Chinese Journal of Dermatology” This study observed that epidermal growth factor significantly stimulated the growth of dermal papilla cells, dermal sheath cells, and fibroblasts in vitro, which supports its use in organotypic culture.
This study reported that a skin equivalent model using human outer root sheath cells and fibroblasts showed the formation of structures similar to human dermis and epidermis within two weeks after transplantation into mice.
33 citations
,
April 2003 in “Oncogene”
August 1994 in “Journal of dermatological science” Different substances affect hair and skin cell growth in various ways, with some promoting and others inhibiting cell proliferation.
1 citations
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April 2017 in “Journal of Investigative Dermatology” This study evaluated the effects of topical glucocorticoids on human skin using non-invasive imaging methods and observed changes such as alterations in skin layer thickness, keratinocyte size, and collagen and elastin signal intensity.
July 2024 in “Journal of Investigative Dermatology” The new skin organoid system effectively mimics human skin for studying its functions, injuries, and diseases.
July 2025 in “Journal of Investigative Dermatology” Collagen scaffolds in cell therapy can transform skin to be more resilient and pressure-responsive.
November 2025 in “Bioengineering” In this study, researchers used a 3D printing technique to spatially pattern human dermal papilla cell spheroids in a collagen matrix, enhancing skin and hair regeneration in a mouse model, with notable upregulation of key genes for hair follicle formation compared to traditional cell cultures.
48 citations
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August 2001 in “Experimental dermatology” This study developed a rapid, cost-effective three-dimensional skin equivalent model using human dermal fibroblasts, collagen, and hair follicles, which closely resembles natural human skin and can be used for autologous transplantation.
August 1994 in “Journal of dermatological science” Different substances affect hair and skin cell growth in various ways.