Search

everythinglearnresearchcommunity

for

Search:↓

Advanced therapies like gene, cell, and tissue engineering show promise for hair regrowth in alopecia, but their safety and effectiveness need more verification.

Rats can't grow new hair follicles after skin wounds, unlike mice, due to differences in gene expression and response to WNT signaling.

Hair growth is influenced by interactions between skin layers, growth factors, and hormones, but the exact mechanisms are not fully understood.

Injected cells show potential for hair growth.

Estrogen is important for keeping adult mouse nipple skin healthy by controlling certain cell signals.

Skin health and repair depend on the signals between skin stem cells and their surrounding cells.

Grouping certain skin cells together activates a growth pathway that helps create new hair follicles.

Activating Notch in adult skin causes T cells and neural crest cells to gather, leading to skin issues.

The experiment showed that human skin grown in the lab started to form early hair structures when special cell clusters were added.

Epidermal stem cells have various roles in skin beyond just maintenance, including forming specialized structures and aiding in skin repair and regeneration.

The skin's basement membrane is specially designed to support different types of connections between skin layers and hair follicles.

The extracellular matrix is crucial for controlling skin stem cell behavior and health.

Activating a protein called β-catenin in adult skin can make it behave like young skin, potentially helping with skin aging and hair loss.

Different types of skin cells play specific roles in development, healing, and cancer.

The new 3D bioprinting method successfully regenerated hair follicles and shows promise for treating hair loss.

Mechanical force is important for the first contact between skin cells and hair growth in mini-organs.

The document concludes that adult mammalian skin contains multiple stem cell populations with specific markers, important for understanding skin regeneration and related conditions.

Mice with a Gsdma3 gene mutation have thicker skin and longer hair follicle openings due to increased β-catenin levels.

Skin cell types develop when specific genes are turned on by removing certain chemical tags from DNA.

Lizards can regrow their tail scales with the same structure, distribution, and gender-specific features as the original ones, and this unique ability is not seen in adult mammals.

The study found that bioengineered hair follicles work when using cells from the same species but have issues when combining human and mouse cells.

Wnt1a-conditioned medium from stem cells helps activate cells important for hair growth and can promote hair regrowth.

Skin stem cells in hair follicles are important for touch sensation.

Hair follicle stem cells are crucial for touch sensation and proper nerve structure in mice.

Macrophage-stimulating protein helps hair grow and can start hair growth phase in mice and human hair samples.

Androgens play a key role in hair growth and disorders like baldness and excessive hairiness.

Collagen XVII is important for skin aging and wound healing.

Apoptosis is essential for human skin development and forming a functional epidermis.

Keratinocytes and adipose-derived stem cells can effectively heal difficult skin wounds.

Retinoic acid-binding proteins in skin are regulated by β-catenin and Notch signalling.