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630-660 / 1000+ resultsresearch Hair Follicle Development of Rex Rabbits Is Regulated Seasonally by Wnt10b/β-Catenin, TGFβ-BMP, IGF1, and EGF Signaling Pathways
Winter provides the best fur quality for Rex rabbits due to seasonal changes in specific signaling pathways.
![Wnt4 increases the thickness of the epidermis in burn wounds by activating canonical Wnt signalling and decreasing the cell junctions between epidermal cells](/images/research/63cb8d88-c4d8-469c-8067-b0244b58ac5b/small/19138.jpg)
research Wnt4 increases the thickness of the epidermis in burn wounds by activating canonical Wnt signalling and decreasing the cell junctions between epidermal cells
Wnt4 protein makes the outer skin layer thicker in burn wounds by turning on a specific healing pathway and loosening the connections between skin cells.
![Functional complexity of hair follicle stem cell niche and therapeutic targeting of niche dysfunction for hair regeneration](/images/research/965189cd-31a5-493d-81c5-a55cacecc5db/small/13296.jpg)
research Functional complexity of hair follicle stem cell niche and therapeutic targeting of niche dysfunction for hair regeneration
Understanding how hair follicle stem cells work can help find new ways to prevent hair loss and promote hair growth.
![Brg1 Governs a Positive Feedback Circuit in the Hair Follicle for Tissue Regeneration and Repair](/images/research/d22892c6-a26b-44eb-ab2c-11e326ca3532/small/19787.jpg)
research Brg1 Governs a Positive Feedback Circuit in the Hair Follicle for Tissue Regeneration and Repair
Brg1 is crucial for hair growth and skin repair by maintaining stem cells and promoting regeneration.
![Aging in hair follicle stem cells and niche microenvironment](/images/research/c250aa11-255b-4a9a-9356-d63fb8b4e124/small/18210.jpg)
research Aging in hair follicle stem cells and niche microenvironment
Aging in hair follicle stem cells leads to hair graying, thinning, and loss.
![As a carrier–transporter for hair follicle reconstitution, platelet-rich plasma promotes proliferation and induction of mouse dermal papilla cells](/images/research/0aa46b2b-c248-4da5-b747-149c67b0b994/small/12565.jpg)
research As a carrier–transporter for hair follicle reconstitution, platelet-rich plasma promotes proliferation and induction of mouse dermal papilla cells
Platelet-rich plasma can help grow more mouse hair follicles, but it doesn't work for human hair follicles yet.
![Topical Application of Oleuropein Induces Anagen Hair Growth in Telogen Mouse Skin](/images/research/ceacbcda-b4d0-41da-b0a6-90cab248749f/small/19675.jpg)
research Topical Application of Oleuropein Induces Anagen Hair Growth in Telogen Mouse Skin
Olive leaf compound oleuropein helps grow hair in mice.
![A role of placental growth factor in hair growth](/images/research/b05f8989-3636-4c9c-bb33-773b9d547941/small/32356.jpg)
research A role of placental growth factor in hair growth
Placental growth factor may help treat hair loss.
![Conventional and novel stem cell based therapies for androgenic alopecia](/images/research/83c1f592-f5bb-434a-aab8-58f683c2bbdd/small/4104.jpg)
research Conventional and novel stem cell based therapies for androgenic alopecia
Stem cell technologies and regenerative medicine, including platelet-rich plasma, show promise for hair restoration in treating hair loss, but more research is needed.
![Analysis of lncRNAs Expression Profiles in Hair Follicle of Hu Sheep Lambskin](/images/research/c9da2678-d3e1-4868-958d-977b449c69ea/small/19286.jpg)
research Analysis of lncRNAs Expression Profiles in Hair Follicle of Hu Sheep Lambskin
lncRNAs may regulate hair follicle development in Hu sheep.
![Perspectives on Hair Evolution Based on Some Comparative Studies on Vertebrate Cornification](/images/research/72d7ff87-ec6d-42c8-88d1-9775e9fbc1ac/small/29271.jpg)
research Perspectives on Hair Evolution Based on Some Comparative Studies on Vertebrate Cornification
Hair in mammals likely evolved from glandular structures, not scales.
![The use of polyethylenimine–DNA to topically deliver hTERT to promote hair growth](/images/research/77437866-b5a1-4cb4-97ea-c57f57d9f93e/small/12861.jpg)
research The use of polyethylenimine–DNA to topically deliver hTERT to promote hair growth
Using polyethylenimine-DNA to deliver the hTERT gene can stimulate hair growth and may be useful in treating hair loss, but there could be potential cancer risks.
![Adipose and Hair Function: An aPPARent Connection](/images/research/28525753-409f-40c1-b615-d5ddd6998215/small/17991.jpg)
research Adipose and Hair Function: An aPPARent Connection
Fat tissue and a specific protein are crucial for healthy hair growth and maintenance.
![RE-ORGA, a Korean Herb Extract, Can Prevent Hair Loss Induced by Dihydrotestosterone in Human Dermal Papilla Cells](/images/research/48319275-e08d-40aa-bea2-f20e0b3ad5c5/small/13426.jpg)
research RE-ORGA, a Korean Herb Extract, Can Prevent Hair Loss Induced by Dihydrotestosterone in Human Dermal Papilla Cells
RE-ORGA, a Korean herb extract, may help prevent hair loss.
![Estrogen modulates mesenchymal-epidermal interactions in the adult nipple](/images/research/961acac0-09c6-4a68-8a30-a351d30174b5/small/19573.jpg)
research Estrogen modulates mesenchymal-epidermal interactions in the adult nipple
Estrogen is important for keeping adult mouse nipple skin healthy by controlling certain cell signals.
![Transcriptome analysis reveals the genetic basis underlying the development of skin appendages and immunity in hedgehog (Atelerix albiventris)](/images/research/c72e0003-03d6-4afc-82a7-7b779ea469fc/small/30782.jpg)
research Transcriptome analysis reveals the genetic basis underlying the development of skin appendages and immunity in hedgehog (Atelerix albiventris)
Genes related to keratin, skin cell differentiation, and immune functions are key in hedgehog skin and spine development.
![Generation of Hair Follicle Germs In Vitro Using Human Postnatal Skin Cells](/images/research/a08a0d95-2964-456f-b907-c87c2aa1ae37/small/19315.jpg)
research Generation of Hair Follicle Germs In Vitro Using Human Postnatal Skin Cells
Scientists created early-stage hair follicles from human skin cells, which could help treat baldness and study hair growth.
![Melatonin Promotes the Development of Secondary Hair Follicles in Adult Cashmere Goats by Activating the Keap1-Nrf2 Signaling Pathway and Inhibiting the Inflammatory Transcription Factors NFκB and AP-1](/images/research/b286cd2b-1122-4056-a6aa-18cfe8cbd352/small/21262.jpg)
research Melatonin Promotes the Development of Secondary Hair Follicles in Adult Cashmere Goats by Activating the Keap1-Nrf2 Signaling Pathway and Inhibiting the Inflammatory Transcription Factors NFκB and AP-1
Melatonin improves cashmere goat hair quality by increasing follicles and reducing skin aging.
![947 Accelerating wound healing mechanisms with cold atmospheric plasma](/images/research/efee270f-c5b4-4e5a-b11c-aed1c3ac14e4/small/12711.jpg)
research 947 Accelerating wound healing mechanisms with cold atmospheric plasma
Cold atmospheric plasma may speed up wound healing and control infections.
![Transcriptome Dynamics Reveal Stage-specific and Melatonin-triggered Gene Expression Patterns During the Cashmere Growth Cycle in Capra Hircus](/images/research/ad482113-aeec-4551-bdbb-3858c899de49/small/34859.jpg)
research Transcriptome Dynamics Reveal Stage-specific and Melatonin-triggered Gene Expression Patterns During the Cashmere Growth Cycle in Capra Hircus
Melatonin can increase cashmere yield by altering gene expression and restarting the growth cycle early.
![Transcriptome analysis reveals the genetic basis underlying the development of skin appendages and immunity in hedgehog (<i>Atelerix albiventris</i>)](/images/research/d4bbf5a1-c540-478c-84bb-1db426fc5839/small/30816.jpg)
research Transcriptome analysis reveals the genetic basis underlying the development of skin appendages and immunity in hedgehog (Atelerix albiventris)
The study found that certain genes are important for hedgehog skin appendage development and immunity, with spines possibly evolving for protection and infection resistance.
![A Mouse Model for Studying Stem Cell Effects on Regeneration of Hair Follicle Outer Root Sheaths](/images/research/a70f8608-f8e4-4b16-a524-781b455905a4/small/19294.jpg)
research A Mouse Model for Studying Stem Cell Effects on Regeneration of Hair Follicle Outer Root Sheaths
The study found that stem cells and neutrophils are important for regenerating hair follicle structures in mice.
![A Preview of Selected Articles](/images/research/8f9ed41c-24ab-4e01-b6c9-c383bfa0f25b/small/33638.jpg)
research A Preview of Selected Articles
New treatments for hair loss, fertility, and wound healing are being explored.
![946 Therapeutic effect of combined platelet-rich plasma strategies on morphea](/images/research/17c68af6-a5a8-47f2-869e-f8ad537be247/small/12699.jpg)
research 946 Therapeutic effect of combined platelet-rich plasma strategies on morphea
Combining platelet-rich plasma injections and gel may effectively treat morphea, improving skin elasticity and reducing pain.
![The Experimental Study on the Effect of Herbal Exrtacts on Hair Growth and Acnes](/images/research/bdbafe9e-8c2e-4aee-a982-23181a56c4e8/small/23242.jpg)
research The Experimental Study on the Effect of Herbal Exrtacts on Hair Growth and Acnes
Rubus coreanum may help hair growth but not through the tested mechanisms, and none of the herbal extracts help with acne.
research Adipose Mesenchymal Stromal Cell-Derived Exosomes Carrying MiR-122-5p Antagonize the Inhibitory Effect of Dihydrotestosterone on Hair Follicles by Targeting the TGF-β1/SMAD3 Signaling Pathway
![Transcription factor FOXC1 positively regulates SFRP1 expression in androgenetic alopecia](/images/research/a8e4192d-db19-4470-a00d-afb454a7890c/small/5217.jpg)
research Transcription factor FOXC1 positively regulates SFRP1 expression in androgenetic alopecia
FOXC1 boosts SFRP1 in hair loss, suggesting new treatments.
![The Hair Follicle as a Dynamic Miniorgan](/images/research/fbec182b-53ae-4ec9-9333-1d61568e55fd/small/12868.jpg)
research The Hair Follicle as a Dynamic Miniorgan
Hair follicles are complex, dynamic mini-organs that help us understand cell growth, death, migration, and differentiation, as well as tissue regeneration and tumor biology.
![Regeneration of fat cells from myofibroblasts during wound healing](/images/research/2aa9b36e-b3d7-4658-9925-da3d5589e0e7/small/19564.jpg)
research Regeneration of fat cells from myofibroblasts during wound healing
Some wound-healing cells can turn into fat cells around new hair growth in mice.