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This study identifies a likely pathogenic homozygous missense variant in the AEBP1 gene in a patient with symptoms of classical Ehlers-Danlos syndrome, suggesting new perspectives for EDS classification and research.

This study found that Sargassum muticum extract and apo-9′-fucoxanthinone promoted hair growth in rat and mouse models by increasing dermal papilla cell proliferation and activating certain signaling pathways.

This study found that glioblastoma cancer stem cells avoid immune suppression by downregulating TLR4, and restoring TLR4 signaling may reduce tumor growth and self-renewal.

This study found that GPC1 is a crucial regulator of angiogenesis in human dermal microvascular endothelial cells, indicating its potential as a target for treating alopecia.

In this study, researchers found that the expression of laminin, collagen type IV, and fibronectin in fetal human skin begins in hair follicle germs and extends to epidermal cells by 21 weeks gestational age.

In this study, growing human hair follicles in a defined glycosaminoglycan hydrogel ex vivo promoted cell survival, proliferation, and activation of hair growth-related signaling pathways, suggesting GAG-based hydrogels could modulate the hair follicle growth cycle.

This study revealed gene expression patterns in yak hair follicles during different growth phases, enhancing the understanding of cell fate specialization and providing insights for yak villus development.

This study found that injecting keratin into the skin of mice promoted hair growth, potentially through keratin's interaction with hair-forming cells and changes in the microenvironment.

This study found that activin A signaling is crucial for hair follicle neogenesis in human dermal papilla 3D cultures combined with mouse epidermal cells.

In this study, transplanted hair follicles from different body sites showed changes in morphology and immune status, suggesting their ability to adapt and function in new recipient areas such as the scalp or eyebrows.

This study suggests that the hairless gene encodes a nuclear factor important for hair follicle integrity, and its absence leads to hair follicle loss and defects in tissue development.

The researchers concluded that baicalin may promote hair growth and follicle proliferation by activating the AKT pathway, suggesting its potential as a treatment for alopecia.

Mesotherapy and platelet-rich plasma treatments may help with hair loss, but their safety and effectiveness are still uncertain.

This review compiles evidence from 20 relevant studies and suggests that platelet-rich plasma-derived extracellular vesicles represent a promising therapeutic option in regenerative medicine, although the authors emphasize the need for standardized protocols due to inconsistencies across studies.

This study explores ear pinna development in mice and reports that elastic cartilage formation is disrupted in a short ear mutant, correlating with increased adult adipocytes and impaired chondrogenesis.

In this source, recent single-cell RNA-sequencing advances reveal significant transcriptional heterogeneity among skin fibroblasts, and the discussion focuses on the distinct subtypes' roles in skin homeostasis, repair, and their evolution in fibrotic diseases like keloid scars and cancer.

This chapter reviews signaling pathways related to androgenic alopecia in dermal papilla cells of balding human scalps, integrating published information and analysis of molecular interactions, without reporting new clinical results.

In this study, researchers at the University of Pennsylvania found that increasing FGF9 levels in wounded mouse skin can lead to the growth of hair follicles.

This study demonstrated how cellular flows and tissue mechanics guide the topological transformations in avian skin, essential for feather follicle development from scales.

This narrative review explores how psychological stress may contribute to premature skin aging by affecting dermal collagen and elastin remodeling through neuroendocrine, molecular, and cellular pathways, highlighting potential therapeutic targets to preserve skin structure and function.

In this study, the researchers reported that a novel exosome-based treatment, EX104, effectively reversed hair follicle miniaturization and promoted hair growth in a mouse model of androgenetic alopecia, showing results comparable to minoxidil and surpassing it in stimulating capillary growth and follicular proliferation.

This study found that melatonin promotes the growth of secondary hair follicles in Inner Mongolian cashmere goats by enhancing the activity and proliferation of dermal papilla cells through involving the Wnt10b gene, though the detailed mechanisms remain undetermined.

This study observed that in a mouse model of androgenetic alopecia, treatments with LTF, 5% minoxidil, and LTF-DPC-EXO significantly promoted hair regeneration compared to the model group, potentially through modulation of the PI3K/AKT signaling pathway.

This study found that exogenous melatonin binds to the nuclear receptor RORα in Inner Mongolia cashmere goats, stimulating secondary hair follicle development and promoting villus growth.

In this study, researchers observed that after mesenchymal cell division in mouse and chicken embryonic skin, elevated migration speed and persistence for 180 minutes contribute to mesenchymal dispersal and preferential recruitment to dermal condensates.

This study found that ocu-miR-205 promotes changes in signaling pathways and shifts in hair follicle phases, affecting Rex rabbit hair density by increasing secondary follicles.

This document details the usage policy for full-text reproduction from Durham E-Theses, providing guidelines for personal, educational, and non-commercial purposes without altering the text.

This review explores hypotheses about hair follicle stem cell function in morphogenesis and cycling, highlights the importance of dermal papilla cells and signaling pathways, and provides no new clinical findings.

This review discusses various tissue engineering approaches for hair follicle regeneration and biomaterials used, emphasizing its potential despite current clinical challenges.

This review discusses the relationship between vitamin K and osteoarthritis, noting that while lower vitamin K levels are associated with increased osteoarthritis, the effects of vitamin K supplementation on the condition remain unclear due to a lack of clinical trials.