January 2025 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that rhamnose can restore hair-inducing gene expression in dermal papilla cells and accelerate hair follicle regeneration by promoting the hair cycle into the anagen phase, suggesting its potential therapeutic application for alopecia treatment.
This study found that GPC1 is a key regulator of angiogenesis in hair follicles and may be an interesting target for addressing alopecia in dermatology research.
This Ph.D. project aims to evaluate the self-assembling potential of hair keratin extracts and study the cellular response to both crude and purified keratins, highlighting their potential applications from biomedical to water remediation.
29 citations
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January 2020 in “BioMed Research International” This study found that sinapic acid promotes the browning of 3T3-L1 adipocytes and may offer therapeutic potential for obesity by influencing mitochondrial biogenesis through the p38 MAPK/CREB signaling pathway.
2 citations
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March 2023 in “Annals of Translational Medicine” This study analyzed trends in tissue expansion research and identified acellular dermal matrix's effect on breast reconstruction complications as a current key topic, with patient-activated controlled expansion as a potential future focus.
December 2022 in “Cureus” This review discusses the hormonal impact on hair growth and the relationship between endocrine disorders and hair changes, reporting no new clinical results.
April 2017 in “Journal of Investigative Dermatology” This study found that hair follicle matrix progenitors differentiate into various layers asynchronously, with early progenitors forming the companion layer and later progenitors generating the inner root sheath and hair shaft.
July 2021 in “British Journal of Dermatology” This case report describes a novel instance of scarring alopecia with features of frontal fibrosing alopecia in a patient with systemic sclerosis, suggesting a potential link between the two conditions not previously reported.
May 2015 in “Journal of The American Academy of Dermatology” The research shows a potential way to regenerate hair using adult cells that have been grown and guided to produce new hair fibers.
12 citations
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April 2022 in “Frontiers in Cell and Developmental Biology” This study found that stabilizing β-catenin in a specific mouse model led to temporarily increased hair density but ultimately accelerated hair follicle aging and hair thinning.
5 citations
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September 2015 in “PubMed” This article provides an overview of the biological process of skin wound healing, detailing the roles of keratinocytes, dermal cells, and trichogenesis without presenting new experimental results.
September 2023 in “Journal of Nutrition and Metabolism” This study found that the ashwagandha extracts ASH-Ext1 and ASH-Ext2 show different pharmacological activities in cell models due to their distinct withanolide proportions, highlighting the need for standardized extraction protocols to ensure consistent therapeutic efficacy.
August 2009 in “Mechanisms of Development” Adult hair follicle cells can create new hair follicles from corneal cells with the right support.
1 citations
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July 2025 in “Genetics Selection Evolution” In this study, using scRNA-seq, researchers detailed the gene expression and cell differentiation processes in goat fetal horn buds, identifying crucial roles for dermal and epithelial cells in horn initiation and highlighting potential genetic factors involved in horn morphogenesis.
66 citations
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June 2004 in “Development” This study found that FGF signaling is necessary for the initiation of feather placode development in chicken embryos, with FGF10 being implicated as an early dermal signal in the process.
January 2007 in “Revista del Centro Dermatológico Pascua” This review discusses female androgenic alopecia, highlighting its potential difference from male androgenic alopecia and notes increased incidence, but reports no new clinical findings.
2 citations
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September 2022 in “Composites Part B: Engineering” This study found that multifunctional peptide-based materials derived from Crassostrea gigas may promote scarless dermal wound healing without affecting intestinal flora through both topical and oral administration.
27 citations
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June 2023 in “Nature” In this study using genetic mouse models, researchers discovered that senescent melanocytes in nevi secrete osteopontin, which activates hair stem cells, enhancing hair growth; this process is mirrored in human hairy nevi, suggesting a potential therapeutic target for regenerative disorders.
April 2021 in “Indian Journal of Animal Research” This study examined the age-related changes in the dermal structure of goat skin, providing baseline data on its histomorphology, histochemistry, and histoenzymology.
June 2024 in “Annals of the College of Medicine Mosul/Annals of the College of Medecine” This study explored the use of microneedling for dermatological disorders, highlighting its benefits like increased collagen and elastin production, dermal thickening, and skin rejuvenation, making it suitable for conditions such as scars, stretch marks, and photoaged skin.
3 citations
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April 2021 in “Elsevier eBooks” This article discusses the structure and functions of the integumentary system and wound healing processes, but it reports no new clinical findings.
May 2023 in “ACS Biomaterials Science & Engineering” This study found that a silk fibroin/sodium alginate scaffold effectively delivers human umbilical mesenchymal stem cells to promote scarless wound healing and hair follicle regeneration in vivo by inducing specific cellular processes and mitigating endoplasmic reticulum stress.
This study suggests that keratin 15 and Id3 proteins play distinct roles in epithelial and dermal cell activities during the regeneration stages of rat vibrissae hair follicles.
1 citations
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July 2021 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that ablative fractional laser treatment significantly alters gene expression related to skin rejuvenation, enhancing wound healing and tissue regeneration processes, and suggests multiple treatments may maximize these effects.
211 citations
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November 2018 in “Nature Cell Biology” This article discusses the coordinated roles of different epidermal stem cells and other cell types in the skin's wound healing process and reports no new experimental results.
February 2024 in “Frontiers in physiology” In this review, the authors explore strategies for inducing scarless skin regeneration by modulating dermal signaling or specific fibroblast subsets to promote the formation of new hair follicles in wounds, particularly focusing on mimicking neonatal skin's regenerative capabilities.
14 citations
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January 2021 in “Scientific Reports” This study found that "micro skin tissue columns" improved wound healing by enhancing re-epithelialization, collagen deposition, dermal remodeling, and reducing inflammation without causing long-term donor site morbidity.
15 citations
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October 2021 in “Frontiers in Pharmacology” This commentary discusses the potential of natural volatiles in medical aromatherapy, highlighting their ability to synergize with other drugs and modulate biological processes, but reports no new results.
8 citations
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January 2011 in “Experimental and Therapeutic Medicine” This review summarizes the characteristics of the peri-malignant melanoma stroma, indicating its potential role in early dermal metastatic migration and increased metastasis risk.
52 citations
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November 2006 in “International Journal of Cosmetic Science” This review discusses the identification and classification of different wrinkle types based on histological features and microanatomy, emphasizing their varying responses to treatments, and reports no new clinical results.