1 citations
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January 2010 in “Shenyang Nongye Daxue xuebao” This study found that combining IGF-1 and EGF in specific concentrations significantly stimulated hair follicle growth in vitro for primary follicles from Liaoning cashmere goats.
August 2025 in “BMC Research Notes” In this study, researchers found that the microRNA profiles of induced pluripotent stem cells (iPSCs) derived from different adult cell types are largely similar, although each line exhibits some unique gene expression, distinct from both their cells of origin and embryonic stem cells.
April 2025 in “Frontiers in Bioengineering and Biotechnology” This research explores the potential of Gel-SHP hydrogels in tissue regeneration, suggesting they could contribute to new methodologies and understanding in wound healing and dermal shell formation, but results are not detailed.
September 2019 in “Journal of Investigative Dermatology” This study developed a 3D skin model with immune and endothelial cells, which may enhance understanding of skin biology and diseases due to its closer approximation to native skin.
January 2002 in “Basic medical sciences and clinics” This review explores hypotheses about hair follicle stem cell function in morphogenesis and cycling, highlights the importance of dermal papilla cells and signaling pathways, and provides no new clinical findings.
January 2023 in “The Egyptian Journal of Hospital Medicine” This review suggests that platelet-rich plasma therapy may be an effective treatment for androgenetic alopecia, with low downtime and minimal adverse effects reported in the studies analyzed.
22 citations
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June 2010 in “Experimental Dermatology” This study reported that patients with alopecia areata have reduced expression of the melanocortin receptor MC2R in their scalp tissues compared to normal scalp, indicating potential involvement in the condition's pathophysiology.
8 citations
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December 2022 in “BMC Genomics” This study revealed gene expression patterns in yak hair follicles during different growth phases, enhancing the understanding of cell fate specialization and providing insights for yak villus development.
5 citations
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January 1993 in “PubMed” In this study, retinoic acid treatments induced glandular and feather formation in embryos by altering positional values and activating specific retinoic acid nuclear receptor gene expression.
1 citations
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June 2000 in “PubMed” This study observed that osteopontin mRNA levels in rat hair follicles vary throughout the hair cycle, peaking during the catagen phase and disappearing in the telogen and anagen phases.
270 citations
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March 2012 in “Dermatologic Surgery” This study found that autologous platelet-rich plasma increased hair growth potential by enhancing dermal papilla cell proliferation and stimulating key signaling pathways in both cell cultures and mice models.
184 citations
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December 2018 in “Nature Communications” This study demonstrated that enhancing human skin constructs with hair follicles through engineered cell organization and vascularization improved hair growth in immunodeficient mice, suggesting potential advances for treating alopecia and chronic wounds.
140 citations
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December 1998 in “Journal of Investigative Dermatology” Apoptosis in hair follicles varies by growth phase, with TGF-β possibly starting the catagen phase.
135 citations
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December 2013 in “Seminars in Cell & Developmental Biology” This review examines the literature on the molecular and cellular makeup of the hair follicle niche and how it influences stem cell behavior during hair regeneration, but does not provide new experimental results.
101 citations
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October 2016 in “Nanomedicine: Nanotechnology, Biology and Medicine” This review reports on the dual aspect of fullerene in skincare, highlighting its beneficial antioxidant properties as well as potential toxicity and skin cell reactions, while identifying areas for future research.
88 citations
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December 2018 in “Advanced Healthcare Materials” This review outlines the current state and future prospects of using layer-by-layer self-assembly for cell encapsulation in biomedical applications, such as cell-based biosensors, transplantation, and tissue engineering, while also discussing its limitations and potential advancements.
36 citations
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July 2014 in “Experimental Dermatology” This narrative piece considers how epigenetic factors may influence the processes of skin wound healing, including hair follicle formation, but it presents no new experimental results.
34 citations
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June 2005 in “Developmental dynamics” This study found that Runx3 deficiency in mice affects hair type and shape, suggesting it may regulate hair formation through interactions between dermal and epidermal layers.
29 citations
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July 1993 in “The journal of investigative dermatology/Journal of investigative dermatology” This article reviews the role of epithelial-mesenchymal interactions in hair follicle development and discusses the challenges of understanding the signals that regulate this complex process; it reports no new results.
14 citations
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January 2021 in “Stem cell research & therapy” This study suggests that interfollicular epidermal keratinocytes with stem-like features may serve as an alternative to follicular keratinocytes for hair regeneration by supporting hair follicle morphogenesis in vivo.
13 citations
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April 1982 in “The Journal of Dermatology” This study found that poly(adenosine diphosphate-ribose) synthesis in human skin varies by cell type and condition, with distinct patterns in psoriatic, cancerous, and normal tissues.
12 citations
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January 2009 in “Stembook” This review addresses the limitations of current engineered skin substitutes for burn patients and highlights potential improvements through stem cell biology and skin morphogenesis, but it reports no new clinical results.
10 citations
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January 2001 in “PubMed” In this study, researchers found that the expression of laminin, collagen type IV, and fibronectin in fetal human skin begins in hair follicle germs and extends to epidermal cells by 21 weeks gestational age.
6 citations
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January 2022 in “Veterinary Sciences” In this retrospective case series, cats with cutaneous lymphocytosis showed a primarily reactive condition with prolonged survival, while dogs exhibited more diverse presentations and clinical outcomes, indicating a complex disease nature.
5 citations
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October 1988 in “Clinics in Dermatology” This article reviews various types of alopecia, their diagnostic features, and patterns, but presents no new clinical findings; the authors discuss multiple mechanisms and classification challenges.
4 citations
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June 2023 in “Journal of developmental biology” In this study, researchers propose that different vertebrate skin appendages, such as hair, feathers, and scales, evolved in parallel from a shared ancestral cell structure associated with teeth, dating back approximately 420 million years ago.
4 citations
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December 2022 in “International Journal of Molecular Sciences” This review discusses the role of zinc and its transporters in skin health and disorders, providing an overview without presenting new clinical results.
4 citations
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September 2020 in “Stem Cell Research & Therapy” In this study, xenobiotic-free human multipotent adult progenitor cells were found to improve wound vascularization and healing in mice, suggesting potential applicability for clinical use in humans.
2 citations
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March 2014 in “Turkderm” Mesotherapy and platelet-rich plasma treatments may help with hair loss, but their safety and effectiveness are still uncertain.
2 citations
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September 2009 in “Pigment Cell & Melanoma Research” This study found that non-cutaneous melanocytes in mice are less sensitive to Kit signaling compared to cutaneous melanocytes, showing dependence on ET3 and HGF signaling.