research Loss of Keratin K2 Expression Causes Aberrant Aggregation of K10, Hyperkeratosis, and Inflammation
Loss of keratin K2 causes skin problems and inflammation.
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research Disrupted Ectodermal Organ Morphogenesis in Mice with a Conditional Histone Deacetylase 1, 2 Deletion in the Epidermis
Mice without certain skin proteins had abnormal skin and hair development.
research Smad4-Dependent Desmoglein-4 Expression Contributes to Hair Follicle Integrity
Smad4 is important for healthy hair follicles because it helps produce a protein needed for hair to stick together and grow.
research The TFIID Subunit TAF4 Regulates Keratinocyte Proliferation and Has Cell-Autonomous and Non-Cell-Autonomous Tumor Suppressor Activity in Mouse Epidermis
TAF4 is important for skin cell growth and helps prevent skin cancer in mice.
research Is Skin Microneedling a Good Alternative Method for Various Skin Defects Removal
Microneedling is a safe and effective way to improve various skin conditions with minimal side effects.
research Retinoid Metabolism Is Altered in Human and Mouse Cicatricial Alopecia
Altered retinoid metabolism in cicatricial alopecia suggests a balanced vitamin A diet may prevent the condition.
research The Proteomic Profile of Hair Damage
Bleaching hair damages protein structure, especially keratin, leading to weakened hair.
research Discovery of Natural Steroid 5 Alpha-Reductase Inhibitors
Natural herbal compounds might treat certain medical conditions by reducing DHT levels, but more research is needed to confirm their effectiveness and safety.
research Penetration Profile and Human Cadaver Skin Distribution of Finasteride from Vesicular Nanocarriers
Ethosomal carriers effectively deliver hair loss drug into skin.
research Skin Health and Integrity
Maintaining skin health is crucial for overall well-being and involves protecting against environmental damage and using skincare products.
research Basic Concepts, Current Evidence, And Future Potential For Gene Therapy In Managing Cutaneous Wounds
Gene therapy shows promise for improving wound healing, but more research is needed for human use.
research Dynamic Wnt5a Expression in Murine Hair Follicle Cycle and Its Inhibitory Effects on Follicular Growth
Wnt5a may slow down hair growth in mice.
research A Dietary Supplement Improves Age-Related Dermatological Changes: Observational, Anecdotal, Spontaneous Study
The dietary supplement significantly improved skin, nails, and hair in older adults.
research Aging Skin: A Window to the Body
Skin aging reflects overall body aging and can indicate internal health conditions.
research Aesthetics in Psychosomatic Dermatology II: Skin Changes Experienced as Cutaneous Disease
People distressed by minor skin changes should consult dermatologists with cosmetic expertise, and a public Cosmetic Dermatology Service with mental health support is recommended.
research The Murine Hair Follicle Is a Melatonin Target
Melatonin directly affects mouse hair follicles and may influence hair growth.
research Variability in Secretion of Growth Factors by Platelets Is Intrinsic to Alopecia Patients Undergoing Platelet-Rich Plasma Therapy
Hair growth treatment results vary because each patient's platelets release different levels of growth factors.
research Forehead, Eyebrow, and Upper Eyelid Lifting
Endoscopic forehead and brow lifting safely and consistently improves aged eyebrows, but may have complications.
research Treatment of Hair Loss
Finasteride and minoxidil are effective for hair loss, but continued research is needed for better treatments.
research Severe Cutaneous Adverse Reactions to Drugs
Some drugs can cause rare but potentially deadly skin reactions, and early treatment and avoiding the drug again are key.
research Evaluation and Treatment of Male and Female Pattern Hair Loss
Early diagnosis and treatment, using finasteride, minoxidil, or hair transplantation, improves hair loss outcomes.
research Generic Development of Topical Dermatologic Products: Formulation Development, Process Development, and Testing
The document concludes that developing generic topical drugs requires ensuring they match the original in quality, composition, and structure, and often involves complex testing and regulatory steps.
research The Transcriptional Repressor CDP (Cutl1) Is Essential for Epithelial Cell Differentiation of the Lung and the Hair Follicle
CDP is crucial for lung and hair follicle cell development.
research Surface Lipids as Multifunctional Mediators of Skin Responses to Environmental Stimuli
Skin surface lipids are important for skin health and altering them could help prevent aging and treat skin conditions.
research Aging of Hair
Hair ages due to genetics and environmental factors, leading to graying and thinning, with treatments available for some conditions.
research Cloning of Wrinkle-Free, a Previously Uncharacterized Mouse Mutation, Reveals Crucial Roles for Fatty Acid Transport Protein 4 in Skin and Hair Development
Fatty acid transport protein 4 is essential for skin and hair development.
research In Vitro Percutaneous Permeation and Skin Accumulation of Finasteride Using Vesicular Ethosomal Carriers
Ethosomes improve finasteride delivery through skin for hair loss treatment.
research What Should It Take to Describe a Substance or Product as 'Sperm-Safe'?
Products should be called 'sperm-safe' only after thorough, well-designed tests.
research Recent Studies on the Delivery of Hydrophilic Drugs in Nanoparticulate Systems
Nanoparticulate systems improve drug delivery by controlling release, protecting drugs, changing absorption and distribution, and concentrating drugs in targeted areas.
research Premature Graying of Hair: Causes, Associations, and Treatments
Premature graying of hair may suggest health issues and currently lacks effective treatments.