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This study found that by using an automated system to analyze skin histology, 108 structural features were significantly affected by age, and it identified four new aging biomarkers and notable sex-based differences in skin aging.

This study found that endothelin produced by hair follicle progenitors activates contractions in dermal sheath cells, facilitating hair follicle regression in the growth cycle.

This study investigated the role of autophagy in human dermal papilla cells and found that inhibiting autophagy accelerates the catagen phase by reducing Wnt/β-catenin signaling. Furthermore, adding ginsenoside Re appears to restore autophagy, suggesting potential benefits for mitigating hair loss linked to autophagy inhibition.

This study demonstrates a method to noninvasively assess lipid classes in rodent sebum via high-field proton NMR, observing significant lipid reductions in rats treated with an SCD1 inhibitor.

This study found that mitochondrial dysfunction and higher oxidative stress in balding dermal papilla cells may contribute to androgenetic alopecia, with antioxidants potentially improving metabolite uptake.

In this study, transplanted hair follicles from different body sites showed changes in morphology and immune status, suggesting their ability to adapt and function in new recipient areas such as the scalp or eyebrows.

In this study, blue light-irradiated nanovesicles derived from human adipose-derived stem cells enhanced dermal fibroblast proliferation and extracellular matrix synthesis, improving skin maintenance and hair follicle regeneration, suggesting a novel therapeutic strategy for skin and hair disorders.

This study found that in C57BL/6 mice, treatment with fermented red ginseng marc, a traditional polyherb formula, or a combination of both, promoted hair growth by enhancing the hair-growth cycle.

This review highlighted that despite existing treatments, chronic nonhealing leg ulcers remain a significant therapeutic challenge, necessitating the development of new methods that are effective, safe, and affordable for patients.

This review discusses the molecular mechanisms of androgen action in human hair follicles and reports no new findings; the authors emphasize the need for further research to improve treatments for hair disorders.

This study describes a protocol for generating hair follicle germ-like organoids from human skin cells, which may aid in alopecia drug discovery and understanding hair follicle regeneration.

This study identified dual epithelial and mesenchymal traits in dermal sheath cells during wound repair, suggesting they could be targeted to enhance healing.

This review highlights that T cells are crucial in regulating hair follicle regeneration and their disruption can lead to alopecia, providing insights into hair disorders related to T cell immune balance and hair follicle regeneration.

This review explores the roles of dermal sheath cells in wound healing, highlighting their multifunctional contributions to inflammation, proliferation, and extracellular matrix remodeling, and proposes new insights into tissue regeneration and repair, especially in differentiating between hairy and non-hairy skin sites.

This review examines advancements in hydrogel formulations aimed at preventing dermal fibrosis and promoting scarless wound healing, highlighting their role in regulating myofibroblast differentiation and controlling the wound microenvironment.

In this study, researchers found that Hdac1 and Hdac2 are crucial for maintaining the quiescence and survival of dermal papilla cells in the hair follicle, regulating the hair cycle by controlling cell-cycle genes and Wnt signaling.

This study found that biomimetic dermal papilla spheres cultured in a specific microenvironment can partially restore hair-inducing ability in high-passage dermal papilla cells in nude mice, resembling the characteristics of primary cells.

In this study, researchers found that the gene LRRC15 was overexpressed in dermal papilla cells from balding areas compared to non-balding areas in patients with androgenetic alopecia.

In this study, D-OCT imaging revealed distinct structural and vascular changes in patients with frontal fibrosing alopecia, highlighting the technique's potential for diagnosing and monitoring the condition's activity.

This study found that Plinest injections improved skin hydration and elasticity in the face, neck, and décolleté and were well-tolerated, with high patient satisfaction over a 4-month follow-up.

In this study, a 21-year-old male with alopecia areata showed complete hair regrowth after following a 100-day holistic Ayurveda treatment, which included Pracchana karma, Gunja-Kalihari lepa application, and Ayurveda formulations, resulting in a SALT-2 score reduction from 66% to 0%.

This study examined dermal papilla cells from hair follicles, finding that gene expression changes linked to wound healing and stem cell activity align with hair follicle regression, which could inform strategies for hair growth and skin rejuvenation.

This study observed that feeding ewes a water-soluble complex of fatty acids increased primary hair follicle bulb diameter and mitotic activity, suggesting a positive correlation with wool growth.

This study found that 10% Citrus aurantium peel oil significantly promoted hair growth in ICR mice by reducing the time needed for hair growth initiation and completion, and by increasing hair length, follicle diameter, and count, showing potential as a hair growth agent.

This study found that lipid supplementation can enhance hair growth by promoting trichogenic gene expression and proliferation of human dermal papilla cells, suggesting lipids as a potential therapeutic target for treating hair loss through HIF-1 signaling pathways.

This study found that exogenous melatonin enhances the development of secondary hair follicles in Cashmere goats by promoting miRNA-mRNA interactions, specifically via the chi-let-7d-5p/WNT2 axis, which suggests a mechanism for melatonin's effects on hair growth involving microRNA regulation.

In this study, subthermal RF-CRET currents were found to alter key molecular mechanisms in dermal papilla cells, promoting proliferation and survival while enhancing markers associated with hair growth and maintenance, suggesting potential benefits for hair regeneration.

In this study, Nigella sativa oil was found to promote dermal papilla cell proliferation and may reduce oxidative stress, suggesting its potential as a hair loss intervention.

This study found that modifying adipose-derived stem cells to overexpress the adhesion protein JAM-A increased the adhesion and resilience of dermal papilla cells in the context of androgenic alopecia, potentially facilitating hair regrowth despite challenges such as damage from dihydrotestosterone and macrophages.

This review highlights the therapeutic potential of hair follicle stem cells in tissue repair and hair regeneration, discussing the molecular mechanisms and the impact of natural compounds on stem cell properties, which may support the development of novel hair loss treatments.