This study found that ocu-miR-205 affects signaling pathways, promoting the apoptosis of dermal papilla cells and influencing hair follicle density in Rex rabbits.
This study found that ocu-miR-205 promotes apoptosis in dermal papilla cells, alters hair follicle signaling pathways, and affects hair density in Rex rabbits.
1 citations
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March 2023 in “Applied sciences” This study found that essential oils boost hair growth activity in dermal papilla cells by scavenging reactive oxygen species and upregulating growth factor biomarkers.
November 2025 in “Bioengineering” In this study, researchers used a 3D printing technique to spatially pattern human dermal papilla cell spheroids in a collagen matrix, enhancing skin and hair regeneration in a mouse model, with notable upregulation of key genes for hair follicle formation compared to traditional cell cultures.
July 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that back skin mesenchyme from mouse embryos can induce hair follicle formation even before dermal condensate formation, but R-spondin-1 alone or with a Bmp receptor inhibitor was not sufficient for hair follicle induction.
May 2023 in “Stem cell research & therapy” This study describes a novel method using force-triggered density gradient sedimentation for efficiently isolating dermal papilla cells from neonatal mouse skin, showing promise for hair follicle regeneration research.
This study found significant differences in mRNA and miRNA expression between yak dermal papilla cells and epidermal hair matrix cells, suggesting important roles for these molecules in hair follicle development.
This study found that ocu-miR-205 promotes the apoptosis of dermal papilla cells and the transformation of hair follicles from growth to regression and resting phases in Rex rabbits.
January 2017 in “Journal of Dermatology and Venereology” This study found that Naringenin and Hesperetin significantly increased the proliferation of hair-related cells and suggested potential as natural hair growth-promoting agents.
January 1989 in “Clinical and Experimental Dermatology” This symposium abstract reports no new experimental results and discusses the pathophysiology of hair growth as presented at an event organized by the Institute of Dermatology.
50 citations
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December 2017 in “British Journal of Dermatology” This study found that ECMs from papillary and dermal papilla fibroblasts support normal basement membrane formation, suggesting potential improvements for therapeutic biomaterials in skin engineering.
2 citations
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January 2022 in “Oxidative Medicine and Cellular Longevity” This study suggests that exosomes from dermal papilla cells can regulate hair follicle stem cell proliferation via the Wnt3a/β-catenin signaling pathway, potentially informing treatment for human hair problems.
306 citations
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April 2019 in “International Journal of Molecular Sciences” This review discusses the protective roles of skin-resident immune cells in maintaining tissue homeostasis and facilitating wound healing, but reports no new experimental findings.
211 citations
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May 2018 in “Trends in cell biology” This review explores recent insights into the diverse cell populations involved in skin development, homeostasis, wound healing, and cancer progression but reports no new results.
128 citations
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August 2020 in “Cell stem cell” In this study, researchers found that extrafollicular progenitors marked by Hic1 are the main contributors to reparative fibroblasts in wound repair, with potential to modulate healing outcomes through genetic and pharmacological interventions.
118 citations
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August 2010 in “Developmental Cell” This study found that the protein MIM is crucial for maintaining cilia and Sonic hedgehog signaling in mesenchymal cells by counteracting Src-mediated phosphorylation of Cortactin, impacting hair follicle formation.
81 citations
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September 2013 in “PLoS ONE” This study identified gene expression differences between dermal papilla cells from primary and secondary hair follicles in Cashmere goats, highlighting their roles in hair follicle morphogenesis.
75 citations
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May 1986 in “Clinics in endocrinology and metabolism” This review explores how androgens and growth hormone influence the development of terminal hairs and sebaceous glands, attributing variability in hirsutism and acne to differing genetic sensitivities to androgens, but reports no new experimental data.
70 citations
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July 2016 in “Aging” This study suggests that dermal adipocytes might play a key role in skin aging due to their transformation into fibrotic structures in chronically photo-damaged skin.
55 citations
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October 2009 in “Clinics in Plastic Surgery” Burn reconstruction improves with new techniques, materials, and tissue engineering.
54 citations
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June 2003 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings” This speculative review discusses hair cycle-dependent fibroblast dynamics and possible impacts on human hair growth, synthesizing current literature without presenting new clinical findings.
49 citations
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September 2007 in “Journal of Investigative Dermatology” The study found that bioengineered hair follicles work when using cells from the same species but have issues when combining human and mouse cells.
45 citations
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July 2009 in “Journal of Investigative Dermatology” This study reported significant upregulation and release of S100A4 in psoriatic skin, which may actively contribute to psoriasis pathogenesis.
38 citations
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February 2016 in “Surgery Journal” This article discusses a wide range of procedures in facial plastic surgery and highlights the recent advancements and trends without reporting new clinical findings.
37 citations
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November 2019 in “Journal of Microbiology and Biotechnology” This study found that loliolide enhanced hair growth-related functions in 3D dermal papilla spheroids by activating AKT/β-catenin signaling pathways, with increased expression of related growth factors and genes.
37 citations
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October 2009 in “Dermatology” This study suggests that the action of minoxidil in stimulating hair growth likely occurs at the follicular dermal papilla, though it does not induce new follicle formation.
35 citations
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November 2020 in “Experimental Dermatology” This study found that upper wound fibroblasts are crucial for hair follicle regeneration during wound healing and suggests that these cells, along with papillary fibroblasts, migrate within the wound.
35 citations
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November 2019 in “Scientific Reports” In this study using a mouse model and human hair follicle cells, shikimic acid was found to promote hair growth and may serve as a new therapeutic agent for alopecia.
35 citations
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July 2018 in “Cell Reports” This study found that the dermal papilla of the hair follicle regulates stem cell quiescence and regeneration by modulating Shh and Wnt signaling pathways, highlighting the importance of signaling cross talk in regeneration.
32 citations
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January 2005 in “Advances in Biochemical Engineering / Biotechnology” This review discusses the unique capacity of fetal skin to heal wounds without scarring and notes that while many factors have been identified, the complete mechanism of fetal wound healing remains unclear.