1 citations
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January 2018 in “Elsevier eBooks” The skin's dermal layer contains true stem cells with diverse functions and interactions that need more research to fully understand.
31 citations
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September 1996 in “Differentiation” The upper dermal sheath can regenerate hair in rats.
14 citations
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January 2021 in “Stem cell research & therapy” Human skin cells with stem-like features can help create new hair follicles and sebaceous glands when combined with other cells.
78 citations
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June 2003 in “Journal of the American Academy of Dermatology” Curly hair shape is determined by the hair bulb.
34 citations
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June 2005 in “Developmental dynamics” Runx3 helps determine hair shape.
1 citations
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January 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” Blocking IL-17 signaling can delay skin aging and improve skin and hair health.
36 citations
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September 2016 in “Biomaterials” Endo-HSE helps grow hair-like structures from human skin cells in the lab.
2 citations
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December 2023 in “Royal Society of Chemistry eBooks” Hair is a complex organ, and understanding its detailed structure and growth phases is crucial for analyzing substances within it.
1 citations
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May 2017 in “Journal of Investigative Dermatology” Topical glucocorticoids thin the skin and change collagen structure.
January 2017 Dermal stem cells help regenerate hair follicles and heal skin wounds.
24 citations
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June 2012 in “Developmental Biology” Dermal papillae cells, important for hair growth, come from multiple cell lines and can be formed by skin cells, regardless of their origin or hair cycle phase. These cells rarely divide, but their ability to shape tissue may contribute to their efficiency in inducing hair growth.
3 citations
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January 2019 in “Advances in stem cells and their niches” Dermal papilla cells are key for hair growth and color, influencing hair type and size, and their interaction with stem cells could help treat hair loss and color disorders.
January 2019 in “Advances in stem cells and their niches” Skin health and repair depend on the signals between skin stem cells and their surrounding cells.
138 citations
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June 2012 in “Genes & Development” Sonic hedgehog signaling is crucial for hair growth and maintaining hair follicle identity.
33 citations
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March 2017 in “British journal of dermatology/British journal of dermatology, Supplement” Human hair follicle dermal cells can effectively replace other cells in engineered skin.
15 citations
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September 2016 in “Biochemical Journal” Wnt proteins from certain skin cells are crucial for normal hair growth and renewal.
2 citations
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March 2018 in “Biotechnology Letters” Scientists created a new cell line from Cashmere goat hair and found that cytokeratin 13 is a unique marker for certain skin cells.
2 citations
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February 2024 in “Nature cell biology” Mechanical forces are crucial for shaping cells and forming tissues during development.
39 citations
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June 2017 in “Scientific Reports” Different lab conditions and light treatment methods change how human skin cells respond to light therapy.
35 citations
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October 2014 in “Journal of Tissue Engineering” Cell-based therapies using dermal papilla cells and adipocyte lineage cells show potential for hair regeneration.
34 citations
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November 2010 in “Development” Activating Notch in adult skin causes T cells and neural crest cells to gather, leading to skin issues.
17 citations
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December 2019 in “Stem Cell Research & Therapy” Grouping certain skin cells together activates a growth pathway that helps create new hair follicles.
2 citations
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August 2012 in “Journal of Dermatological Science” The gene HDC is important for the development of hair follicles in newborn mice.
April 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” Sweat gland development involves two unique skin cell programs and a temporary skin environment.
102 citations
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August 2008 in “Genes & Development” Laminin-511 is crucial for early hair growth and maintaining important hair development signals.
87 citations
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July 2016 in “Development” Blocking β-catenin in skin cells improves hair growth during wound healing.
32 citations
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December 2015 in “Journal of Investigative Dermatology” Prominin-1 expressing cells in the dermal papilla help regulate hair follicle size and communication but don't aid in skin repair.
15 citations
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February 2012 in “Journal of Tissue Engineering and Regenerative Medicine” The best method for transplanting skin cells to regenerate hair follicles is the Hemi-vascularized sandwich method, as it produces more mature follicles and promotes hair growth.
63 citations
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September 2009 in “Regenerative Medicine” Scientists found a way to grow human hair cells in a lab that can create new hair when transplanted.
37 citations
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April 2017 in “npj Regenerative Medicine” PDGF signaling is crucial for maintaining and renewing hair follicle stem cells, which could help treat hair loss.