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This chapter reviews differences in dermatological treatments and conditions between male and female patients, particularly noting the impacts of sex steroids on various skin processes, but presents no new clinical findings.

Androgens can cause hair growth in some areas and hair loss on the scalp.

This study suggests that the paradoxical effects of androgens on hair growth are due to differential gene expression in hair follicles, possibly established during embryogenesis.

This study demonstrated that an engineered human skin equivalent can generate follicle-like structures resembling fetal skin, highlighting the role of the dermal compartment in directing epithelial cell fate in vitro.

This review evaluates the clinical use of composite dermal-epidermal skin substitutes, with a focus on advancements such as the "BioMask" for facial skin trauma, highlighting the potential of 3D bioprinting and bioengineered skin in improving wound treatment and reconstruction.

In this study, researchers used a 3D printing technique to spatially pattern human dermal papilla cell spheroids in a collagen matrix, enhancing skin and hair regeneration in a mouse model, with notable upregulation of key genes for hair follicle formation compared to traditional cell cultures.

In this study with a rat muscle defect model, decellularized muscle matrix demonstrated better integration, neovascularization, and myogenesis compared to commercially available acellular dermal matrices, and also showed trends toward reduced inflammation and fibrosis after 30 and 60 days.

This review highlights the potential of bioengineered dermal scaffolds in tissue engineering to enhance wound healing by mimicking the dermal structure and supporting cellular processes, while also discussing recent advancements and challenges in scaffold technology.

This study found that JAK inhibitors promote hair regrowth in both mice and human alopecia areata cases by blocking key immune pathways involved in disease development.

This review discusses dermal cell heterogeneity in wound healing and scar formation, highlighting the varied roles of different fibroblasts and the potential of skin substitutes without presenting new clinical results.

This study found that inducing hair follicles into the anagen-onset stage in mice enhances the immune response to a topically applied DNA vaccine against anthrax.

In this study, poly (ɛ-caprolactone)–chitosan–poly (vinyl alcohol) nanofibrous scaffolds used on canine skin wound models were found to significantly accelerate healing rates of excision and burn wounds, without inducing immunogenic reactions.

This study observed that cutaneous microwounds created by fractional photothermolysis heal differently from typical wounds, displaying rapid re-epithelialization and limited inflammation, which may help reduce scar formation by delaying collagen remodeling and minimizing myofibroblast activation.

This article aims to enumerate and describe the types of tissue degeneration observed in various dermatopathological conditions, offering beneficial insights for residents studying the deterioration of skin tissues due to inflammatory, infective, drug-induced, or neoplastic stimuli.

Inhibiting PGD2 and using dermal papilla cells may improve skin and hair regeneration.

This study found that deferiprone significantly reduced dermal fibrosis and skin thickness in mice with chronic kidney disease treated with Omniscan, suggesting iron's role in gadolinium chelate toxicity and nephrogenic systemic fibrosis.

This study found that "micro skin tissue columns" improved wound healing by enhancing re-epithelialization, collagen deposition, dermal remodeling, and reducing inflammation without causing long-term donor site morbidity.

This article contains the late-breaking abstracts from the 39th Annual Conference of the American Society for Laser Medicine and Surgery and does not present new research results.

This study developed a validated murine model of hypertrophic scar contraction, demonstrating similarities to human skin and observing graft contraction and tissue characteristics over time.

This study found that radiofrequency treatment, with or without hydrolyzed collagen, increased dermis thickness, neocollagenesis, and FGF2 overexpression in rat skin tissue.

Male and female mice have different skin thickness, and hormones affect their skin and hair growth differently.

In this study, transgenic mice expressing Msx-2 developed flaky skin with hyperproliferation and misalignment in epidermal cells, suggesting Msx-2 plays a role in skin and appendage growth control.

This review discusses mechanisms of wound healing impairment in leptin-deficient murine models used for diabetic research, and reports no new clinical results; the authors emphasize the need for further study.

This review discusses the basic biology of apoptosis and its relevance to skin diseases, without presenting new research findings.

This study found that treatment with PTH-CBD stimulated hair growth in mice with alopecia areata, with increased levels of beta catenin indicating activation of the Wnt pathway.

This review summarizes the current understanding of Wnt signaling in relation to its roles in tissue regeneration and cancer progression and discusses recent medical advancements targeting this pathway for therapeutic purposes.

This review found that most studies support the effectiveness and safety of using hyaluronic acid fillers and laser treatments together for facial rejuvenation, but highlights that the evidence is limited to small, nonrandomized studies and additional research is necessary.

This study found that polycaprolactone (PCL) in facial fillers led to more cell proliferation and vascular activity than hyaluronic acid (HA) in Wistar rats, suggesting enhanced tissue regeneration effects with PCL.

This review discusses the formation and structure of the cornified cell envelope in the epidermis, highlighting biochemical pathways and genetic factors, but presents no new experimental results.

This review discusses current advancements in mesenchymal stem cell-based therapies for skin repair and rejuvenation, focusing on therapeutic strategies, particularly highlighting the potential of neonatal and placenta-derived MSCs, and reports no new clinical results.