835 citations,
October 2008 in “Nature Genetics” Lgr5 is a marker for active, long-lasting stem cells in mouse hair follicles.
349 citations,
January 2005 in “The FASEB journal” Human skin can make serotonin and melatonin, which help protect and maintain it.
290 citations,
December 2017 in “Journal of The American Academy of Dermatology” Alopecia areata is an autoimmune condition causing hair loss, influenced by genetics, stress, and diet, and may be prevented by a high soy oil diet.
114 citations,
February 2012 in “International Journal of Dermatology” Smoking harms the skin, causing early aging and increasing cancer risk, but stopping smoking can improve skin health.
82 citations,
February 2017 in “Cold Spring Harbor Perspectives in Biology” The TGF-β family helps control how cells change and move, affecting skin, hair, and organ development.
59 citations,
September 2008 in “Experimental dermatology” Both mouse and rat models are effective for testing alopecia areata treatments.
51 citations,
July 2010 in “Trends in Endocrinology and Metabolism” Prolactin may play a significant role in skin and hair health and could be a target for treating skin and hair disorders.
47 citations,
June 1996 in “International Journal of Legal Medicine” Hair analysis for drugs needs a better understanding of how drugs enter hair, considering factors like hair structure and pigmentation.
31 citations,
July 2017 in “Clinical Science” MicroRNAs are important for skin health and could be targets for new skin disorder treatments.
25 citations,
April 2021 in “npj Regenerative Medicine” Mathematical modeling can improve regenerative medicine by predicting biological processes and optimizing therapy development.
16 citations,
March 2008 in “Dermatologic Surgery” Hydrogen peroxide's effects on wound healing in hair transplants are unclear, and it may slow healing and increase scarring.
8 citations,
September 2016 in “Journal of Investigative Dermatology” Mice with more Flightless I protein grew back their claws better after amputation.
7 citations,
August 2022 in “Nature communications” A specific group of slow-growing stem cells marked by Thy1 is crucial for skin maintenance and healing in mice.
2 citations,
August 2020 in “Clinical, Cosmetic and Investigational Dermatology” The hair-growth formula with L-cystine helps protect and grow hair cells.
June 2022 in “Scientific Reports” Prevelex, a polyampholyte, can create a cell-repellent coating on microdevices, which can be useful in biomedical applications like hair follicle regeneration.
January 2019 in “Springer eBooks” Transplanting skin cells is a safe, effective, and affordable treatment for vitiligo.
June 2008 in “Dermatologic Surgery” Hydrogen peroxide may have both positive and negative effects on wound healing, and its safe concentration for hair transplant surgery is unclear.
70 citations,
January 2014 in “International review of cell and molecular biology” Keratin proteins are crucial for healthy skin, but mutations can cause skin disorders with no effective treatments yet.
10 citations,
June 2021 in “EMBO reports” When skin blisters, healing the wound is more important than growing hair, and certain stem cells mainly fix the blisters without helping hair growth.
4 citations,
January 2017 in “PubMed” Epidermal growth factor helps stem cells heal wounds and regenerate hair follicles faster.
3 citations,
January 2023 in “Agronomy” KDML105 bran extract may help with hair growth and prevent hair loss.
June 2023 in “Frontiers in Bioengineering and Biotechnology” The conclusion is that accurately replicating the complexity of the extracellular matrix in the lab is crucial for creating realistic human tissue models.
1 citations,
December 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” Keeping β-catenin levels high in mammary cells disrupts their development and branching.
April 2024 in “Materials today bio” The CuCS/Cur wound dressing helps regenerate nerves and heal deep skin burns by rebuilding hair follicles.
79 citations,
January 2015 in “Journal of Materials Chemistry B” Smart biomaterials that guide tissue repair are key for future medical treatments.
1 citations,
January 2024 in “Theranostics” Exosomes show promise for future tissue regeneration.
124 citations,
December 2016 in “Pharmaceuticals” TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.
84 citations,
January 2018 in “Biomaterials Science” Sericin hydrogels heal skin wounds well, regrowing hair and glands with less scarring.
27 citations,
July 2017 in “European Journal of Dermatology” Certain microRNAs are linked to various skin diseases and could be used to diagnose and treat these conditions.
2 citations,
March 2019 in “Journal of Histochemistry and Cytochemistry” Neuronatin is found in specific cells within rat testis, hair follicles, tongue, and pancreas, suggesting it has various roles in tissue development and function.