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A boy with severe Vitamin D-resistant rickets did not respond to treatment and lacked a common symptom, suggesting a need for alternative treatments.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Both HPSAM and PLS methods accurately measure minoxidil and tretinoin concentrations.

New research is needed to create better drugs that block the enzyme responsible for conditions like male baldness and prostate enlargement.

Treating hirsutism in women often requires a mix of medications and cosmetic methods for best results.

HO-1 helps skin health and healing but can worsen melanoma; it's a potential treatment target for skin diseases.

Modified pep7, named EPM peptide, effectively promotes hair growth at low concentrations and works well with minoxidil.

Itraconazole may cause low platelet and white blood cell counts.

Current research explores hair growth drugs, while future research aims for personalized treatments.

Different drugs can treat high male hormone levels in women, but they have various effects and some may harm a fetus.

Various treatments exist for alopecia areata, but none are completely satisfactory; choice depends on age, disease extent, and preference.

Retinoids are effective for skin conditions like severe acne and psoriasis but must be used with caution due to potential side effects and risks during pregnancy.

Ion-paired risedronate significantly increases skin penetration without irritation compared to risedronate alone.

New androgen receptor modulators show promise for treating diseases like prostate cancer and muscle wasting.

Male pattern baldness may be caused by factors like poor blood circulation, scalp tension, stress, and hormonal imbalances, but the exact causes are still unclear.

High doses of fluconazole can cause reversible hair loss.

The document highlights various patents for new compounds with potential treatments for multiple diseases, including cancer, hormonal disorders, and diabetes.

Finasteride almost fully depletes allopregnanolone in rat brains and enhances 20α-DHP, but doesn't change 3α-DHP levels.

The document reviews 20 U.S. patents from July and August 2004 about new drug forms, cancer treatments, aroma chemicals, statin drugs, and various chemical production methods.

Minoxidil effectively treats hair loss, with better results in women.

Fluconazole is an effective antifungal medication with potential side effects and lacks official analytical methods for its determination.

Leflunomide and methotrexate are equally effective for rheumatoid arthritis but have different side effects.

Skin organoids are a promising new model for studying human skin development and testing treatments.

Multimodal minoxidil microemulsion is more effective in treating hair loss than minoxidil alone.

New pregnane derivatives are effective at inhibiting an enzyme linked to hair loss and reducing oil gland activity.

New pregnane derivatives were more effective than finasteride at inhibiting a key enzyme for male pattern baldness.

International medical graduates outperformed U.S. graduates on an internal medicine exam.

Finasteride and analogues separated using LC-MS-MS technique.

Some supplements may help with hair loss, but there's not enough strong evidence to recommend them without doctor advice.

Ethnic differences in hair and skin are significant and under-researched, requiring tailored dermatologic treatments and more study.