research The Role of Cytochrome P-450 in Dermatology
Cytochrome P-450 enzymes in the skin help break down various substances and could be targeted to treat skin conditions.
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research Quintaquinone, a Merosesquiterpene from the Yellow Sponge Verongula cf. Rigida
A new compound from a sponge strongly inhibits an enzyme linked to male-pattern hair loss without being toxic at low levels.
research Relative Binding Affinity of Novel Steroids to Androgen Receptors in Hamster Prostate
New steroids were effective in blocking male hormone receptors in hamster prostates.
research Direct Quantitative Digital Autoradiography Of Testosterone Metabolites In The Pilosebaceous Unit: An Environmentally Advantageous Trace Radioactive Technology
The method accurately measures testosterone metabolites with high sensitivity and low environmental impact.
research Facile One-Pot Synthesis of Substituted Hydantoins from Carbamates
Scientists in India found a safer and efficient way to make a type of medicine called hydantoins from carbamates, which also worked well in making the seizure medicine, Ethotoin.
research The First Syntheses of 16β-Chloro- and 16β-Bromo-Cyproterone Acetate
Scientists made two new chemicals that might help treat diseases caused by male hormones.
research Effect of Aminopterin on Epithelial Tissues
Aminopterin effectively improves skin conditions but has toxic side effects that need careful monitoring.
research Remarks on the Hormonal Background of the Male Equivalent of Polycystic Ovary Syndrome
Men might have a version of the female disease, polycystic ovarian syndrome, shown by changes in hormone levels and early baldness, but more research is needed to fully understand it.
research Placental Extracts, Proteins, and Hydrolyzed Proteins as Active Ingredients in Cosmetic Preparations for Hair Loss: A Systematic Review of Available Clinical Evidence
Placenta products might help with hair loss, but more research is needed.
research Investigations on Kaempferol, Quercetin, and Other Flavonoids in Aquatic Plants of Iraqi Marshlands
Flavonoids in Iraqi marshland plants have potential health benefits like antioxidant and anti-inflammatory effects.
research Oxidative Stress: Insights into the Pathogenesis and Treatment of Alopecia
Hair loss can be caused by stress, aging, and harmful substances that create an imbalance in the body's natural processes.
research Peptide-Based Biomaterials
Peptides are being used to create biomaterials that can help diagnose and treat diseases.
research Antifibrogenic Activities of Novel Vitamin D3 Analogs Are Dependent on VDR Expression in Human Fibroblasts
New vitamin D3 forms need the vitamin D receptor to reduce fibrosis in human cells.
research Nanocarriers for Improved Delivery of Angiotensin-(1-7)
Nanocarriers like liposomes and cyclodextrins improve how angiotensin-(1-7) is delivered in the body.
research Serum Vitamin Levels in Different Categories of Androgenetic Alopecia Subjects
Smoking and drinking can lower vitamin levels and potentially trigger early hair loss, but overall vitamin levels don't seem to affect hair loss duration.
research Steroid 5α-Reductase Inhibitors
New steroidal compounds could be effective for treating conditions related to 5α-reductase enzyme activity.
research Hypersensitivity Reactions to Anticoagulant Drugs
Allergic reactions to blood thinners are rare but can be serious, requiring careful management and alternative treatments.
research The Interplay of Oxidative Stress and Immune Dysfunction in Hashimoto’s Thyroiditis and Polycystic Ovary Syndrome: A Comprehensive Review
Oxidative stress and immune dysfunction are linked to both Hashimoto's thyroiditis and polycystic ovary syndrome, with diet and specific treatments important for managing these conditions.
research Anti-Anginal and Beta-Adrenoceptor Blocking Drugs
Beta-blockers and anti-anginal medications have various side effects and interactions that require careful monitoring and individualized treatment.
research Vitamins
High doses of certain vitamins can cause serious side effects and health risks.
research Fullerene C60 with Cytoprotective and Cytotoxic Potential: Prospects as a Novel Treatment Agent in Dermatology
Fullerene C60 shows promise as a new treatment for various skin conditions.
research Highly Efficient Nucleophilic Addition of Alkyl Grignard Reagents to 17-Ketosteroids in the Presence of Cerium(III) Chloride: Synthesis of 17α-Propyl-17β-Hydroxy-4-Androsten-3-One, an Androgen Receptor Antagonist
Adding cerium(III) chloride to Grignard reagents improves the making of compounds that could treat prostate issues and hair loss.
research Biomacromolecules/Modified Halloysite Composite Hydrogel Used as Multifunctional Wound Dressing
The new hydrogel is good for wound dressing because it absorbs water quickly, has high porosity, can release drugs, fights bacteria, and helps wounds heal with less scarring.
research Differential Expression of Retinoic Acid-Synthesizing (RALDH) Enzymes During Fetal Development and Organ Differentiation in the Mouse
Different enzymes are active in different parts of developing mouse organs.
research Ichthyosis
The document concludes that accurate diagnosis of ichthyosis is crucial for treatment and genetic advice, and ongoing research is needed for better therapies.
research Clinical Findings, Cutaneous Pathology, and Response to Therapy in 21 Patients With Keratosis Pilaris Atrophicans
The study found that Keratosis Pilaris Atrophicans is a genetic skin condition that starts in childhood, involves inflammation and scarring, and current treatments are only somewhat effective.
research Nanotechnology in Dermatology
Nanotechnology in dermatology shows promise for better drug delivery and treatment effectiveness but requires more safety research.
research Drugs and Hair Loss: Mechanisms and Clinical Implications
Some medications can cause hair loss, but stopping the drug usually leads to recovery within 3 months.
research Culture of the Human Pilosebaceous Unit, Hair Follicle, and Sebaceous Gland
The article concludes that developing in vitro models for human hair structures is important for research and reducing animal testing, but there are challenges like obtaining suitable samples and the models' limitations.
research A Case of Peeling Skin Syndrome Successfully Treated With Topical Calcipotriol
Peeling skin syndrome was successfully treated with a vitamin D cream.