research Cardiovascular risk markers in premature canities
This study found that patients with premature greying of hair had significant abnormalities in cardiovascular risk markers, including elevated IL-6 levels, compared to healthy controls.
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research Serum total thiol level in Acne Vulgaris Patients and its relation to oxidative stress
This study found that individuals with acne vulgaris had significantly higher serum total thiol and thiol disulfide levels, as well as a reduced total thiol/thiol disulfide ratio, compared to healthy controls.
research Risk of Safety Events in Vitiligo Patients: A Retrospective Real‐World Data Study in the US
This study found that patients with vitiligo in the United States had higher rates of autoimmune conditions, infections, and skin cancer compared to matched controls, with higher vitiligo prevalence in Asian and Hispanic populations.
research The genetic basis of dermatophytosis skin infection susceptibility
In this study, researchers conducted a large genome-wide association meta-analysis and found 30 significant genetic loci linked to the risk of dermatophytosis, shedding light on the roles of keratin biology, skin barrier defects, immune dysfunction, and obesity in the disease.
research Comparative Study of Myocardial Biomarkers Among Women with and Without Polycystic Ovarian Syndrome (Pcos) in Nigeria
This study observed that Nigerian women with PCOS have significantly higher levels of myocardial biomarkers (MYO, cTnI, CK-MB), indicating potential chronic, subclinical myocardial injury in this population.
research Hair follicle stem cell-derived secretome protects astrocytes in an in vitro ischemia/reperfusion model
This study found that hair follicle stem cell-derived secretome mitigated cell death, apoptosis, and inflammation while upregulating neurotrophic factors in astrocytes exposed to oxygen-glucose deprivation, an in vitro ischemic stroke model, suggesting potential therapeutic benefits in stroke recovery.
research Limosilactobacillus fermentum MF10 promotes hair growth through upregulation of Wnt/β-catenin signaling in C57BL/6 mice
In a depilation mouse model, this study found that Limosilactobacillus fermentum MF10 promoted hair growth and increased follicle size by activating skin Wnt/β-catenin signaling and modulating gut microbiota, with effects comparable to the positive control finasteride.
research Peroxisome Proliferator Activated Receptor-Gamma Tissue Expression and Gene Polymorphism in Alopecia Areata in an Egyptian Sample
This review evaluates the role of the nuclear receptor PPAR- in skin diseases, highlighting its regulation of inflammation, lipid metabolism, and immune response, and suggests that PPAR-agonists could be promising therapies for conditions like psoriasis and atopic dermatitis.
research Serum Plasma Thiol Evaluation in Chronic Telogen Effluvium Patients
This study observed that female patients with chronic telogen effluvium had significantly lower levels of total thiol, thiol-disulphide, and disulphide compared to healthy controls, indicating a disruption in oxidative stress balance.
research Effect of Nutritional Teaching Program on Clinical Outcomes for Breast Cancer Patients Undergoing Chemotherapy
This study found that a nutritional teaching program significantly reduced chemotherapy side effects and improved the health status of breast cancer patients undergoing chemotherapy.