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This review discusses how targeting apoptosis pathways in hair and skin cells can inform the development of novel therapies, but it reports no clinical findings.

This narrative review suggests that nutraceutical insulin-sensitizing agents like myo-inositol, alpha-lipoic acid, and vitamins may improve glycemic control and reduce inflammation in insulin resistance-related skin disorders; however, more robust long-term trials are needed to confirm these findings and establish treatment regimens.

In this study, researchers identified key lncRNAs and target genes potentially involved in the transformation of the hair follicle cycle, which could advance understanding of lncRNAs' roles in hair follicle development.

This review highlights the role of chronic stress, oxidative stress, and immune processes in the development of Hashimoto’s thyroiditis and polycystic ovary syndrome, emphasizing the potential of antioxidants in their treatment based on the existing literature.

Photobiomodulation effectively stimulates hair growth and reduces hair loss.

This review discusses the potential of ginseng and its metabolites for treating hair loss and reports no new clinical findings.

This study found that chronic UVR exposure in mice and humans leads to a permanent loss of papillary fibroblasts in the upper dermis, which is associated with changes in the extracellular matrix.

This case report identifies an adolescent with symptoms indicative of Dunnigan-type partial lipodystrophy, emphasizing the need for early diagnosis to manage associated metabolic complications and improve self-esteem.

This study found that p21 is much more highly expressed in normal melanocytes compared to melanoma cells, suggesting a potential target for preventing melanoma progression through cell cycle repair processes.

Nanoparticles can improve drug delivery to hair follicles but struggle to penetrate deeper skin layers.

This review summarizes recent progress in microneedle-based drug delivery systems and discusses their potential impact on cellular mechanisms and immunization signaling pathways, highlighting the need for further development in fabrication methods.

This review discusses transdermal drug delivery using hydrogel-forming microneedles and highlights their potential for disease treatment, but notes challenges in their clinical application.

This review discusses the design, properties, and potential applications of smart microneedles, with no new clinical results presented.

This review discusses hydrogel-forming microneedles for non-invasive drug delivery in dermatology and reports no new clinical results, emphasizing their promise in improving treatment adherence and patient comfort.

This review discusses the integration of biodegradable biomaterials with drugs and stem cells for diabetic wound repair, but reports no new clinical results and highlights the need for further translation to clinical practice.

This review article highlights how hair follicle-targeting drug delivery systems enhance therapeutic outcomes and reduce side effects for treating conditions like androgenetic alopecia and acne vulgaris. The authors discuss current formulations and evaluate their performance in both preclinical and clinical settings.

Male hormones control a specific gene in hamster skin, with different hormones having varying effects.

This review discusses transdermal drug delivery using hydrogel-forming microneedles and highlights their potential and challenges for clinical application, but it reports no new clinical findings.

Confocal Laser Scanning Microscopy (CLSM) is a useful tool for studying how drugs interact with skin and diagnosing skin disorders, despite some limitations.

In this study, researchers investigated a regulatory network in cashmere goat embryos and found that fibroblast growth factor 10, alongside non-coding RNAs, significantly influences hair follicle cell proliferation, offering insights into the biology of hair follicles in cashmere goats.

This case report describes an instance of hair thread tourniquet syndrome in an infant, successfully treated through surgical release of the constricting hair.

This study reviews lipid-based nanocosmeceuticals and reports that they enhance therapeutic effectiveness in dermatological applications by improving skin hydration, reducing wrinkles, and effectively managing conditions like psoriasis and eczema, though further large-scale trials and regulatory alignment are needed for clinical use.

This study suggests a potential link between hair dye exposure during periconception or pregnancy and certain adverse obstetric and pediatric outcomes, but the evidence remains preliminary and uncertain.

In this ex vivo and in vitro study, researchers found that capacitive resistive electrical transfer therapy increased cell proliferation and reduced cell death in hair follicles from patients with androgenic alopecia, suggesting potential benefits for alopecia treatment.

This review examines the mechanisms, recent findings, and strategies to enhance mesenchymal stem cells' therapeutic effects in skin wound healing, but reports no new research results.

In this study, researchers used high-resolution MRI to distinguish anatomical differences in the scalp and hair follicles between tertiary androgenetic alopecia and severe alopecia areata, identifying subcutaneous tissue layer thickness as a key discriminative factor with high diagnostic value.

This study found that the addition of SPACE peptide significantly enhanced the penetration of amniotic membrane stem cell metabolites in mice, with only very mild irritation observed.

Minoxidil effectively controls blood pressure in severe cases, but has serious side effects and causes hair growth in women.

This study found that topical trypsin application after hair removal in mice led to cell death at the follicular papilla, which delayed hair growth and pigmentation.

This study found that TRPV3 ion channels on human epidermal keratinocytes suppress cell proliferation, induce cell death, and trigger a proinflammatory response, suggesting a role in cutaneous inflammatory processes.