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Finasteride can cause lasting sexual, emotional, and cognitive issues, with varying severity.

5α-reductase inhibitors can cause sexual problems, higher risk of aggressive prostate cancer, and depression.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

β-Catenin signaling is involved in brain cell growth after injury and could be a therapy target.

Isotretinoin's effects and side effects, like birth defects and depression, might be due to it causing cell death in various cells.

Mood stabilizers like lithium and anticonvulsants have side effects that can lead to patients stopping their medication, and managing these effects is important for treatment adherence.

Antidepressants may improve or resolve scalp dysesthesia in most patients.

Hormone treatment for transgender patients may not need to be stopped before surgery, but more research is needed, especially on estrogen.

Menopause and aging can affect women's quality of life and sexuality, but hormone therapies may help alleviate these issues.

Antidepressants called SSRIs can cause skin problems, bleeding risk, and other side effects.

Antidepressants, 5α-reductase inhibitors, and isotretinoin can cause long-lasting sexual dysfunction.

Finasteride and minoxidil work best together for hair loss.

Using finasteride or dutasteride may cause long-lasting erectile dysfunction.

Women with PCOS often have hair loss, which is linked to acne or excess body hair but not to worse hormone or metabolic issues.

Polycystic Ovary Syndrome is common but often undiagnosed, and early treatment is important to prevent health problems.

The document concludes that future heart disease research should account for sex-specific differences to improve diagnosis, treatment, and outcomes.

New alopecia treatments aim for better results and fewer side effects.

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.

A comprehensive approach to educating patients and managing side effects is crucial for improving adherence to multiple sclerosis treatments and patient quality of life.

Researchers developed a 3D model of human hair follicle cells that can help understand hair growth and test new hair loss treatments.

Botulinum toxin has potential for treating various skin conditions and improving wound healing.

Finasteride caused long-term sexual and non-sexual side effects in young men with hair loss.

Kids with alopecia areata may experience more stress but not necessarily feel more anxious or depressed than others.

The document suggests creating a validated score to diagnose Cushing's Syndrome and considers plasma steroid profiling as a simpler diagnostic method.

Drug repositioning is becoming more targeted and efficient with new technologies, offering personalized treatment options and growing interest in the field.

Women with PCOS often have mood disorders and a lower quality of life, and treatment should focus on both physical and mental health.

Negative expectations can cause adverse effects in patients even without active treatment, and managing this nocebo effect involves better communication and patient-clinician relationships.

Using psychological treatments can help manage skin conditions along with regular medical care.

The review suggests that understanding and treating the psychological aspect of skin disorders is important and calls for more collaboration in this field.

People with hair loss feel more depressed and anxious, especially women, and need help managing emotions and beliefs about their condition.