research Steroid 5α-Reductase 2 Deficiency Leads to Reduced Dominance-Related and Impulse-Control Behaviors
Mice lacking steroid 5α-reductase 2 show less aggression and better impulse control.
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research Dutasteride, A Novel Dual 5-Alpha Reductase Inhibitor, Reduces Serum DHT to a Greater Extent Versus Finasteride and Achieves Maximal Reduction in a Larger Proportion of Patients
Dutasteride reduces DHT more effectively than finasteride.
research Topical Odorant Application of the Specific Olfactory Receptor OR2AT4 Agonist, Sandalore, Improves Telogen Effluvium-Associated Parameters
Sandalore® improves hair growth and quality in people with hair loss.
research Distinct Conditions Support a Novel Classification for Bradykinin-Mediated Angioedema
The conclusion suggests a new way to classify bradykinin-mediated angio-oedema based on different causes and its possible link with urticaria, which could improve diagnosis and treatment.
research Repurposing Steroidogenesis Inhibitors for the Therapy of Neuropsychiatric Disorders: Promises and Caveats
Drugs for hormone-related conditions might help treat mental disorders but could have serious side effects.
research A Machine Learning and Network Framework to Discover New Indications for Small Molecules
A machine learning model called CATNIP can predict new uses for existing drugs, like using antidepressants for Parkinson's disease and a thyroid cancer drug for diabetes.
research Comedonal Lupus: A Case Study of a 60-Year-Old Moroccan Man
A man was diagnosed with a rare form of lupus after showing unique skin symptoms that responded well to treatment.
research PH Dependence of the Coiled-Coil Structure of Keratin Intermediate Filament in Human Hair by 13C NMR Spectroscopy and the Mechanism of Its Disruption
Keratin structure in hair is stable at pH 5-6 but disrupts between pH 6-7.
research Quintaquinone, a Merosesquiterpene from the Yellow Sponge Verongula cf. Rigida
A new compound from a sponge strongly inhibits an enzyme linked to male-pattern hair loss without being toxic at low levels.
research Incidence and Risk Factors for Alopecia in Survivors of Critical Illness: A Multi-Centre Observational Study
Many survivors of critical illness, especially those with sepsis, experience hair loss.
research Dermal-Epidermal Cross-Talk: Differential Interactions With Microvascular Endothelial Cells
Human dermal fibroblasts help microvascular endothelial cells grow, but not vice versa.
research A Case of Pili Torti in a Young Adult Domestic Short-Haired Cat
A young cat had a rare hair condition with twisted hair shafts but stayed healthy.
research Comparison of Effectiveness of Topical Tacrolimus and Betamethasone with Soft Paraffin in the Treatment of Patchy Alopecia Areata
Betamethasone is more effective than Tacrolimus and soft paraffin for hair regrowth in patchy alopecia areata.
research Alopecia in Harlequin Mutant Mice Is Associated with Reduced AIF Protein Levels and Expression of Retroviral Elements
Harlequin mutant mice have hair loss due to low AIF protein levels and retroviral element activity.
research Examining Polyquaternium Polymers Deposition on Human Excised Hair Fibers
Certain polymers can stick to hair and increase volume, working best at a pH of 7 to 9.
research Comparison of Finasteride, Metformin, and Finasteride Plus Metformin in PCOS
Finasteride and metformin both help treat PCOS, but using them together works best.
research Effect of Ethanolic Extract of Hibiscus Rosa Sinensis Flowers on Hair Growth in Female Wistar Rats
Hibiscus flower extract slowed down hair growth in rats.
research Scalp Cooling in the Prevention of Anthracycline-Induced Alopecia
Scalp cooling prevented hair loss in half of the patients, despite significant side effects.
research Automatic Artificial Hair Implant: Safety and Efficacy in Androgenetic Alopecia. A Prospective Study with a Highly Biocompatible Fiber
Implant safely and effectively treats hair loss.
research Targeting a Fibrotic Bottleneck May Provide an Opening in the Treatment of LUTS
New treatments targeting fibrosis could improve urinary symptoms in BPH.
research Topical Valproate Solution for Hair Growth
Topical valproate can effectively promote hair growth.
research Mechanism of Apoptotic Regulation of Follicular Regression
The document concludes that understanding how hair follicles naturally die and regenerate is important for insights into organ development and could impact health and disease treatment.
research Mineralocorticoid Receptor Antagonists Stimulate Human Hair Growth Ex Vivo
Eplerenone, a mineralocorticoid receptor antagonist, was found to promote hair growth in human hair follicles.
research Molecular Correlation With Clinical Outcomes in an Open Label Clinical Trial of Oral Tofacitinib in Patients With Alopecia Areata
Tofacitinib helped most patients with alopecia areata regrow hair and changes in immune cells were linked to the treatment's effectiveness.
research Implementation of a Teletriage System Improves Access to Dermatologic Care in an Underserved Clinic: A Retrospective Review
Using a teletriage system greatly increased access to skin care for uninsured Latino immigrants at a clinic.
research The Effect of Cilostazol on Hair Growth: A Novel Therapeutic Option for the Treatment of Hair Loss
Cilostazol may help hair grow and could be a new treatment for hair loss.
research Retinoic Acid Is Not Involved in Fluconazole-Induced Alopecia: Evaluation in a Human Cohort and Rat Model
Retinoic acid is not linked to hair loss from fluconazole use.
research Gene Therapy: Recent Advances and Applications in Dermatology
Gene therapy shows promise for treating skin disorders and cancer, but faces technical challenges.
research The Effect of Relative Humidity on the Spreading of Ethanol on Human Hair Fibers
Ethanol spreads well on hair at low humidity but less so at higher humidity due to water condensation.
research Association of Risk Factors with Female Pattern Hair Loss
Older age, family history, and low iron levels increase the risk of female hair loss.