research Zinc Therapy in Dermatology: A Review
Zinc is effective for treating various skin conditions, including warts and acne.
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research Alopecia Areata: A Multifactorial Autoimmune Condition
Alopecia areata is an autoimmune disease causing patchy hair loss, often with other autoimmune disorders, but its exact causes are unknown.
research Potential of Nanoparticles as Permeation Enhancers and Targeted Delivery Options for Skin: Advantages and Disadvantages
Nanoparticles can improve skin drug delivery but have challenges like toxicity and stability that need more research.
research Penetration and Storage of Particles in Human Skin: Perspectives and Safety Aspects
Particles around 100 nm can penetrate and stay in hair follicles without passing through healthy skin, making them safe for use in topical products and useful for targeted drug delivery.
research Human αβ and γδ T Cells in Skin Immunity and Disease
Certain types of T cells are essential for healthy skin and play a role in skin diseases, but more research is needed to improve treatments.
research Follicular and Percutaneous Penetration Pathways of Topically Applied Minoxidil Foam
Minoxidil foam enters hair follicles and skin for hair growth.
research Pathways to Inflammation: Acne Pathophysiology
Acne is caused by genetics, diet, hormones, and bacteria, with treatments not yet curative.
research The Role of Macrophages in Skin Homeostasis
Macrophages are vital for skin healing, hair growth, salt balance, and cancer defense.
research Feline Atopic Dermatitis: A Retrospective Study of 45 Cases (2001–2012)
Cats with atopic dermatitis often have severe, year-round itching and respond well to certain treatments.
research JAK Inhibitors and Alopecia Areata
JAK inhibitors help regrow hair in alopecia areata patients, improving their quality of life.
research RANK as a Therapeutic Target in Cancer
RANK is a key target in breast cancer treatment due to its role in tumor growth and bone metastasis.
research Significance of the S100A4 Protein in Psoriasis
The S100A4 protein is more common in psoriatic skin and could be a target for treating psoriasis.
research Stem Cell Factor/c-Kit Signaling in Normal and Androgenetic Alopecia Hair Follicles
SCF and c-Kit decrease in AGA hair follicles, possibly affecting hair pigmentation and growth.
research Alopecia Areata in C3H/HeJ Mice Involves Leukocyte-Mediated Root Sheath Disruption in Advance of Overt Hair Loss
Hair loss in mice starts with immune cells damaging hair roots before it becomes visible.
research The Role of Vitamin D in Non-Scarring Alopecia
Low vitamin D might be linked to certain types of hair loss, and supplements could help, but more research is needed.
research MicroRNAs in the Skin: Role in Development, Homeostasis, and Regeneration
MicroRNAs are important for skin health and could be targets for new skin disorder treatments.
research LPA3, A Unique G Protein-Coupled Receptor For Lysophosphatidic Acid
LPA3 is crucial for embryo implantation and links LPA to prostaglandin signaling.
research Regulatory T Cells Are Required for Normal and Activin-Promoted Wound Repair in Mice
Regulatory T cells are essential for normal and improved wound healing in mice.
research Skin Manifestations Among GATA2-Deficient Patients
Patients with GATA2 deficiency show early skin symptoms that help diagnose the condition.
research Breakdown of Immune Tolerance in AIRE-Deficient Rats Induces a Severe Autoimmune Polyendocrinopathy–Candidiasis–Ectodermal Dystrophy–Like Autoimmune Disease
AIRE-deficient rats developed severe autoimmune disease similar to APECED, useful for testing treatments.
research Effects of Imiquimod on Hair Follicle Stem Cells and Hair Cycle Progression
Imiquimod cream activates hair follicle stem cells and causes early hair growth by changing immune cells and certain protein expressions.
research An Intrinsic Oscillation of Gene Networks Inside Hair Follicle Stem Cells: An Additional Layer That Can Modulate Hair Stem Cell Activities
Gene network oscillations inside hair stem cells are key for hair growth regulation and could help treat hair loss.
research Hair Removal Using a Pulsed-Intense Light Source
Pulsed-intense light can significantly reduce hair, with effectiveness depending on treatment number and timing, and has mild side effects.
research Transfollicular Enhancement of Gel Containing Cationic Niosomes Loaded with Unsaturated Fatty Acids in Rice Bran Semi-Purified Fraction
The gel with special fat-loaded particles from rice bran could be an effective skin treatment for hair loss.
research Correlation of Monosynaptic Field Potentials Evoked by Single Action Potentials in Single Primary Afferent Axons and Their Bouton Distributions in the Dorsal Horn
The study found that nerve signals are stronger when there are more connection points, but not necessarily denser, along the nerve's path in the spine.
research Identification of an Intronic Regulatory Element Necessary for Tissue-Specific Expression of Foxn1 in Thymic Epithelial Cells
A specific DNA region is crucial for Foxn1 gene expression in thymus cells but not in hair follicles.
research Perforin Expression by Cutaneous Gamma Delta T Cells
Gamma delta T cells in the skin help with healing and defense but can also cause autoimmune issues, and more research is needed to understand how they are activated.
research Mechanisms of Tolerance and Potential Therapeutic Interventions in Alopecia Areata
Targeting immune tolerance issues in Alopecia Areata could restore hair growth and maintain remission.
research Platelet-Derived Growth Factor Regulates the Proliferation and Differentiation of Human Melanocytes in a Differentiation-Stage-Specific Manner
PDGF-BB helps young melanocytes grow but stops mature ones from growing, and it makes melanocytes more specialized.
research Exacerbation of Alopecia Areata During Pegylated Interferon Alpha-2b and Ribavirin Therapy, Possibly Due to the Collapse of Hair Follicle Immune Privilege
A woman's hair loss worsened after starting hepatitis C treatment due to immune changes in her hair follicles.