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Anti-IL-12/IL-23 antibody therapy effectively treats psoriasiform skin lesions in IBD patients.

The document concludes that mouse models are helpful but have limitations for skin wound healing research, and suggests using larger animals and genetically modified mice for better human application.

Some drugs can cause rare but potentially deadly skin reactions, and early treatment and avoiding the drug again are key.

Polymeric nanoparticles show promise for treating skin diseases.

Niosomes are a promising, stable, and cost-effective drug delivery system with potential for improved targeting and safety.

Stem cell offspring help control their parent stem cells, affecting tissue health, healing, and cancer.

Teriflunomide helps reduce multiple sclerosis symptoms and is safe for most patients.

The immune system plays a key role in tissue repair, affecting both healing quality and regenerative ability.

A protein from certain immune cells is key for new hair growth after skin injury in mice.

Two main types of fibroblasts with unique functions and additional subtypes were identified in human skin.

Eph receptors and ephrins may be promising targets for treating diseases, but more understanding is needed for effective and safe therapies.

Stem cells help heal skin wounds by moving and changing roles, working with other cells, and needing more research on their activation and behavior.

Different types of skin cells play specific roles in development, healing, and cancer.

The skin is a complex barrier for drug penetration, but understanding its structure and interactions can improve drug delivery methods.

Male and female bodies respond differently to stress, influenced by hormones and development stages, with implications for stress-related diseases.

Hair follicle development and microbes help regulatory T cells gather in newborn skin.

Regulatory T-cells are important for healing and regenerating tissues in various organs by controlling immune responses and aiding stem cells.

Alopecia areata is an autoimmune condition causing hair loss due to the immune system attacking hair follicles, often influenced by genetics and stress.

Special fiber materials boost the healing properties of certain stem cells.

Alopecia areata involves immune activation in the scalp, suggesting treatments targeting TH1, TH2, and IL-23 pathways.

Blocking JAK-STAT signaling can lead to hair growth.

The document concludes that recognizing and treating cutaneous lupus erythematosus early is crucial for managing the skin and potential systemic symptoms.

Memory T cells in the skin balance staying put and moving into the blood, clustering around hair follicles, and increasing in number after infection.

Male and female skin differ due to hormones, affecting conditions like hair loss, acne, and skin cancer, and suggesting a need for gender-specific treatments.

Nanoparticles improve drug delivery through the skin but more research is needed on their long-term effects and skin penetration challenges.

Bioprinting could improve wound healing but needs more development to match real skin.

The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.

Keratinocytes help heal skin wounds by interacting with immune cells and producing substances that kill pathogens.

Cathepsin L is essential for normal hair growth and development.

Targeting the IL-23/IL-17 pathway effectively treats several inflammatory skin diseases.