39 citations
,
January 2015 in “Journal of Electroanalytical Chemistry” In this study, a novel electrochemical sensor using a molecularly imprinted polymer was developed for the sensitive detection of minoxidil, successfully measuring its concentration in real samples.
38 citations
,
January 2014 in “International Journal of Endocrinology” This review highlights that children with adrenal disorders may experience neurological and psychiatric symptoms, with potential long-term cognitive and behavioral effects from excess glucocorticoids.
37 citations
,
January 2009 in “The Journal of Dermatology” In this study, hair follicle stem cells from ND-GFP transgenic mice were observed to be pluripotent, effectively repairing peripheral nerve and spinal cord injuries in mouse models.
37 citations
,
September 2008 in “The American journal of surgical pathology” This study concluded that hair follicle hyperplasia found in pseudolymphomatous folliculitis can also occur in genuine cutaneous lymphomas, potentially as a coincidental result of underlying pathological processes.
36 citations
,
April 2014 in “Experimental Dermatology” This article discusses the need for a personalized and stratified therapeutic approach for vitiligo, utilizing current knowledge and expertise, but it does not report new clinical results.
33 citations
,
October 2010 in “Journal of Dermatological Science” This study suggests that human and mouse hair follicle stem cells may support nerve repair and provide a practical source of stem cells for neurological therapies.
29 citations
,
May 2020 in “npj Regenerative Medicine” This review discusses the role of the immune niche in hair follicle regeneration and its impact on different forms of alopecia, highlighting research gaps and potential therapeutic strategies.
29 citations
,
January 2010 in “Methods in Enzymology” This review discusses five genetic fate mapping methods used to study cell behaviors during development and regeneration, detailing the necessary tools and considerations without reporting new experimental results.
28 citations
,
December 2019 in “Skin appendage disorders” This review discusses medication-induced gray hair repigmentation, highlighting that certain anti-inflammatory drugs and melanogenesis stimulators can cause diffuse repigmentation, though evidence remains low-quality and these medications are not currently indicated for this purpose.
25 citations
,
December 1992 in “Seminars in cell biology” This review discusses how epidermal Langerhan's cells and dermal cells may influence keratinocyte environments, potentially aiding in the formation of stem cell niches and cellular variety in the basal layer, without providing novel results.
23 citations
,
August 2018 in “Biochimica and biophysica acta. Molecular and cell biology of lipids” This article reviews the roles of lesser-known secreted phospholipase A2 isoforms in various biological processes, such as immune suppression, metabolic regulation, epidermal hyperplasia, and male reproduction, without reporting new clinical findings.
22 citations
,
October 2019 in “Cerebral cortex” This study found that testosterone and dihydrotestosterone are crucial for synaptic transmission and spine density in male hippocampal neurons, suggesting sex-specific effects of neurosteroids on brain development.
22 citations
,
September 2018 in “Medical Clinics of North America” This article reviews the biological causes and treatment options for facial aging but reports no new clinical findings.
21 citations
,
October 2009 in “Biochemical Engineering Journal” This review discusses various approaches to treating alopecia, including drug therapy and hair transplantation, but reports no new research findings; the authors highlight the need for novel techniques like cell culturing.
20 citations
,
October 2018 in “Aesthetic Plastic Surgery” This review discusses the potential mechanisms of platelet-rich plasma in facial rejuvenation and reports no new clinical results, indicating a theoretical basis for its use in tissue regeneration.
19 citations
,
April 2015 in “Developmental Dynamics” This study reports that dynamic interactions between stem cells and their niche, influenced by macro-environmental factors, regulate regenerative behavior in integument pattern formation.
18 citations
,
September 2013 in “Technology” This study introduces a new multimodal imaging technology to visualize and quantify cell dynamics in natural skin over long durations, demonstrated in GFP bone marrow-transplanted mice, to study dynamic skin regeneration.
18 citations
,
February 2012 in “Experimental Dermatology” This study found no significant association between selected gene variants and female pattern hair loss, suggesting these genes might not be involved in its development.
16 citations
,
January 2006 in “The Aging Male” This review discusses various skin diseases with endocrinological origins and reports no clinical results, highlighting the need for interdisciplinary understanding in diagnosis.
16 citations
,
November 2005 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings” This review discusses various aspects of hair color, including its formation and evolutionary variations, based on research presented at the 4th Intercontinental Meeting of Hair Research Societies 2004, without providing new experimental results.
14 citations
,
March 2017 in “Brain research” This study suggests that ovarian cycle-related progesterone and neurosteroids regulate α2-subunit expression of GABA-A receptors in the hippocampus through a pathway independent of progesterone receptors, potentially affecting brain conditions linked to the menstrual cycle.
13 citations
,
April 2022 in “Frontiers in oncology” This review discusses the early phases of melanomagenesis and the factors influencing melanoma cell variability and reports no new clinical results.
11 citations
,
August 2016 in “Journal of dermatological treatment” This study evaluated the effects of tip cryotherapy on idiopathic guttate hypomelanosis lesions, finding that 82.3% of treated lesions showed significant improvement after four months compared to only 2% of control lesions, with minimal side effects.
11 citations
,
April 2013 in “SpringerPlus” This study reports that melanocytes form a defined photoresponsive network in the skin that reads environmental light cycles and may influence the sleep-waking cycle similar to the pineal gland.
10 citations
,
June 2019 in “International Journal of Cosmetic Science” This review discusses the potential benefits of phytochemicals for hair care and emphasizes the need for more robust preclinical and clinical studies, without reporting new clinical results.
9 citations
,
December 2020 in “International Journal of Medical Sciences” This article reviews the development and use of induced pluripotent stem cell models and artificial organoids for studying neurodevelopmental disorders, but it reports no new clinical findings.
9 citations
,
January 2017 in “Annals of Dermatology” In this study of a TRPS type I patient, many genes related to keratin and hair development were down-regulated in balding scalp areas, providing new insights into TRPS and hair morphogenesis.
8 citations
,
December 2020 in “The FASEB Journal” Blocking adenosine A2B receptor may prevent or treat hearing loss.
8 citations
,
February 2013 in “Central European Journal of Biology” This article discusses melanocyte development from neural crest cells and reports no new experimental results; the authors suggest a broader range of functions for melanocytes than previously recognized.
7 citations
,
February 2019 in “International Journal of Dermatology” This review discusses factors influencing hair pigmentation and the etiology of canities, noting the lack of clarity in underlying mechanisms and calling for further research on treatment options.