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Taking 5 mg/day finasteride can cause side effects in women with hair loss, but these are usually mild and fade over time, making the treatment beneficial in the long run.

Blocking IL-12/IL-23 does not help with hair loss in alopecia areata for mice or humans.

Finasteride may lower cholesterol and slow heart disease progression.

Dihydrotestosterone can be made from dehydroepiandrosterone in skin cells without needing testosterone.

The document concludes that new treatments are needed to better manage acne and reduce side effects related to current therapies.

Fadrozole and finasteride change gene expression related to sex hormones and thyroid hormones in frog larvae development.

Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.

Some breast cancer chemotherapy can cause permanent hair loss.

New genes and pathways are important for testosterone production and male sexual development.

Women with acne and PCOS should be checked for insulin resistance and related symptoms.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Human skin produces sex hormones like estrogen and testosterone, influenced by ARO and StAR, which may affect skin elasticity and hair growth.

Ciproterone acetate improves hair regrowth and acne in most female patients.

The document concludes that HAIR-AN syndrome should be considered when a patient shows severe hyperandrogenism and insulin resistance after excluding tumors.

Understanding how DHT works is important for diagnosing and treating hormone-related disorders.

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

Higher estrone-to-estradiol ratios are linked to worse glucose metabolism and insulin resistance in women with PCOS.

All five human steroid 5α-reductase enzymes are found in the endoplasmic reticulum.

Whale oil significantly promotes hair growth and may be a safe, effective alternative to minoxidil.

Diet changes hormone levels in pregnant ewes by affecting metabolism, not placental synthesis.

The trial aims to test if spironolactone is an effective acne treatment for women without the side effects of current treatments.

PCOS is a complex condition in women that can lead to health issues, and lifestyle changes are the best management approach.

Mice without the enzyme HSD17B3 still produce normal testosterone, suggesting they have different ways to make it compared to humans.

Both estrogens and androgens are important for health in both males and females.

Avicennia Marina extract and avicequinone C can reduce hair loss hormone production and increase hair growth factors, suggesting they could be used to treat androgenic alopecia.

Sebocytes play a key role in controlling androgen levels in human skin.

Social media data can help track and predict COVID-19 symptoms and trends.

Social media data can help track COVID-19 symptoms and predict the pandemic's status.

Understanding glycans and enzymes that alter them is key to controlling hair growth.