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November 2002 in “Endocrine practice” This case report describes a post-menopausal woman with severe hirsutism whose high testosterone levels decreased after gonadotropin suppression, indicating residual hormone-producing tissue responsive to gonadotropins.
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December 1997 in “Journal of The European Academy of Dermatology and Venereology” In this study, 85.9% of 120 hirsute Saudi women exhibited elevated androgen levels, suggesting the need for a comprehensive hormonal evaluation to identify underlying causes of hirsutism.
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November 1996 in “Journal of Cutaneous Medicine and Surgery” Hormones, especially androgens, play a key role in causing acne, and treatments like hormone control pills and hormone-blocking medications can help.
June 2026 in “Romanian Journal of Medical Practice” This case report describes a 72-year-old woman with a steroid cell tumor of the ovary, highlighting the critical role of imaging, biochemical evaluation, and pathology in diagnosing and managing hormonally active ovarian tumors that cause virilization in postmenopausal women.
In this review, the authors discuss various skin conditions linked to hyperandrogenism, such as acne and alopecia, with a focus on androgen-targeted therapies, suggesting these are generally more effective than non-androgen-targeted options.
April 2026 in “JOJ Dermatology & Cosmetics” This review highlights that effective management of PCOS-related dermatological issues, such as hirsutism and acne, requires a multidisciplinary approach involving hormonal therapies, metabolic interventions, and lifestyle changes.
February 2026 in “Frontiers in Endocrinology” In this case study, a woman with congenital adrenal hyperplasia experienced substantial improvement in musculoskeletal and neurobehavioral symptoms after low-dose testosterone therapy, highlighting its potential role in managing chronic glucocorticoid overtreatment effects.
February 2026 in “Molecular Imaging and Radionuclide Therapy” In this study, male patients treated with 150 mCi of radioactive iodine showed no negative impact on fertility, but long-term studies with larger groups are needed to further assess hormonal effects and sperm health after this treatment.
September 2024 in “Electronic Journal of General Medicine” In this case series study, two Peruvian women with virilizing ovarian tumors called Sertoli-Leydig cell tumors showed clinical improvement and normalization of androgens after surgical treatment, highlighting the diagnostic challenge of these rare presentations at different ages.
September 2024 in “Advanced medical journal” In this study, spironolactone was found to be a safe and effective treatment for acne in women over 25 with abnormal hormone levels, while younger women with normal hormone levels showed less response.
This report describes a complex case of postmenopausal hyperandrogenism with virilization and concurrent rare ovarian tumors, highlighting the critical role of interdisciplinary collaboration in diagnosing and managing such challenging scenarios.
January 2024 in “Journal of the Endocrine Society” In this study, correlations between urinary and serum androgen metabolites were examined in girls aged 6-13, revealing that summed urinary metabolites strongly correspond with circulating androstenedione and testosterone levels, though individual variations depend on participant characteristics such as age and body measurements.
January 2023 in “Scholars journal of applied medical sciences” This study found that polycystic ovary syndrome and idiopathic hirsutism are the main causes of hirsutism in the women studied at a gynecology clinic, accounting for about 94% of cases.
November 2022 in “Journal of the Endocrine Society” This case report highlights a rare ovarian steroid cell tumor as the cause of androgen excess in a 36-year-old woman and underscores the importance of thorough preoperative workup to avoid unnecessary surgery.
September 2022 in “Curēus” This case report describes a 61-year-old female with hyperandrogenic symptoms, where an ovarian hemangioma with stromal luteinization was identified and surgically removed, resulting in improved symptoms.
September 2022 in “Research Square (Research Square)” This study found that while pro-, pre-, and synbiotics may have beneficial effects on certain PCOS-related outcomes, the certainty of this evidence is low to very low.
In this study, facial hypertrichosis occurred in 10% of women treated with isotretinoin for acne, but it resolved spontaneously after the treatment ended.
November 2021 in “Khyber Medical University Journal” This case report highlights that uncommon ovarian tumors like sclerosal stromal tumors can cause hirsutism and virilization in postmenopausal women and lead to androgen secretion, despite typically being hormonally inactive.
October 2021 in “Turkderm” This study found that women with post-adolescent acne experience marked menstrual irregularities, polycystic ovaries, androgenetic alopecia, hirsutism, and metabolic syndrome, but insulin resistance and dyslipidemia may not significantly contribute to their acne's pathogenesis.
September 2021 in “International Journal of Biomedicine” This study found that SNPs in the MVK, ARPC1B, and CA2 genes may indicate a genetic predisposition for severe acne related to steroidogenesis.
May 2021 in “Journal of Advances in Internal Medicine” This case report describes a 13-year-old with DSD raised as female, exhibiting hoarseness and clitoral enlargement, with hormonal assessments not indicating common related deficiencies.
January 2021 in “touchREVIEWS in Endocrinology” Surgery successfully treated a hidden ovarian tumor causing hair loss and excess hair growth in a postmenopausal woman.
November 2020 in “Elsevier eBooks” This source outlines various antiandrogen and androgen inhibitor drugs used to treat cutaneous disorders of hyperandrogenism, detailing their mechanisms, uses, dosages, and side effects, with emphasis on spironolactone, finasteride, dutasteride, and oral contraceptives.
This study found that neonatal administration of finasteride reduced sensitivity to alcohol's motor-stimulating effects and increased preference for novelty and initial alcohol consumption in rats, suggesting a role in alcohol vulnerability.
April 2017 in “Journal of evolution of medical and dental sciences” This study reports that polycystic ovary syndrome was the most common cause of hirsutism among Indian patients, with 70% of cases associated with this condition.
January 2017 in “Springer eBooks” The document explains various skin conditions and their treatments.
January 2016 in “Journal of SAFOG” This study observed that androgenic hormone levels were higher in high school girls with PCOS phenotypes accompanied by menstrual disorders, particularly oligomenorrhea.
January 2016 in “Springer eBooks” Pubertal acne is linked to hormonal changes, affects quality of life, and is treated similarly to adult acne.
December 2015 in “Вестник дерматологии и венерологии” This article reviews research on androgen hormone profiles and the effects of androgens on hair follicles related to androgenetic alopecia, but reports no new experimental results.
July 2015 in “Cambridge University Press eBooks” The document concludes that treatments for female hair loss and excess body hair are available, but managing expectations is important.