research Partial Proteasome Inhibitors Induce Hair Follicle Growth by Stabilizing Beta-Catenin
Certain inhibitors applied to the skin can promote hair growth by maintaining a key hair growth signal.
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research Non-Invasive Human Skin Transcriptome Analysis Using mRNA in Skin Surface Lipids
The conclusion is that analyzing RNA from skin oils is a promising way to understand skin diseases.
research Enhancement of Hair Growth Through Stimulation of Hair Follicle Stem Cells by Prostaglandin E2 Collagen Matrix
Prostaglandin E2 collagen matrix may help stimulate hair growth.
research Activating an Adaptive Immune Response from a Hydrogel Scaffold Imparts Regenerative Wound Healing
A special gel scaffold was made that speeds up wound healing and skin regeneration, even though it breaks down faster than expected.
research Exploring the Physicochemical Compatibility of Minoxidil in Combination with Different Active Pharmaceutical Ingredients in Ready-to-use Vehicles for Alopecia Treatment
The study investigated the compatibility of TrichoSol™ and TrichoFoam™ as vehicles for minoxidil and other active pharmaceutical ingredients in alopecia treatments. The formulations were stable for 90-180 days at room temperature, with less than 10% degradation of APIs. No physical changes were observed, and the preservative system was effective. These vehicles are suitable for personalized alopecia treatments.
research Autophagy Induces Hair Follicle Stem Cell Activation and Hair Follicle Regeneration by Regulating Glycolysis
Autophagy helps activate hair stem cells and hair growth by changing their energy use to glycolysis.
research Human TMEM2 Is Not a Hyaluronidase but a Regulator of Hyaluronan Metabolism
Human TMEM2 does not break down hyaluronan but helps control its metabolism.
research P120-Catenin Regulates Epidermal Inflammation in a Cadherin-Dependent Manner
p120-catenin helps control skin inflammation by regulating cadherin levels.
research Antioxidants and Mitochondrial Bioenergetics: Charnoly Bodies in Neurodegenerative Diseases, Cardiovascular Disorders, and Cancer
Antioxidants may help improve mitochondrial health and could be used to treat diseases related to cell damage.
research The Endocannabinoid Tone Regulates Human Sebocyte Biology
The endocannabinoid system affects oil production and inflammation in skin cells.
research Intermolecular NH2-/Carboxyl-Terminal Interactions in Androgen Receptor Dimerization Revealed by Mutations That Cause Androgen Insensitivity
Mutations at Val-889 and Arg-752 disrupt key interactions in the androgen receptor, affecting its function.
research Caffeine’s Mechanisms of Action and Its Cosmetic Use
Caffeine in cosmetics may reduce cellulite, protect skin, and stimulate hair growth, but more research is needed on its use and effects.
research Keratin Hydrogels Support the Sustained Release of Bioactive Ciprofloxacin
Keratin hydrogels can slowly release effective ciprofloxacin to prevent infections.
research Replicative Stress, Stem Cells, and Aging
Maintaining DNA health in stem cells is key to preventing aging and tissue breakdown.
research Anti-Acne Agents Attenuate FGFR2 Signal Transduction in Acne
Anti-acne medications may work by reducing the activity of a protein involved in acne development.
research Synergistic Effect of Carbodiimide and Dehydrothermal Crosslinking on Acellular Dermal Matrix
Combining DHT and EDC improves the strength and stability of PADM scaffolds for tissue engineering.
research Engineering Pro-Regenerative Hydrogels for Scarless Wound Healing
Hydrogels could lead to better treatments for wound healing without scars.
research Enhanced Cutaneous Wound Healing by Functional Injectable Thermo-Sensitive Chitosan-Based Hydrogel Encapsulated Human Umbilical Cord-Mesenchymal Stem Cells
A new hydrogel with stem cells from human umbilical cords improves skin wound healing and reduces inflammation.
research Membrane Androgen Receptors May Mediate Androgen Reinforcement
Androgen self-administration might be controlled by membrane receptors, not nuclear ones.
research Curcumin And Cancer Biology: Focusing Regulatory Effects In Different Signalling Pathways
Curcumin may be an effective and safer anticancer agent by regulating key cell pathways.
research Morphological Changes in Human Head Hair Subjected to Various Drug Testing Decontamination Strategies
Different hair cleaning methods caused varying levels of damage to the hair's outer layer.
research Testosterone Therapy in Men: Clinical and Pharmacological Perspectives
Testosterone therapy aims to treat hormone deficiencies and various conditions safely and effectively, but requires careful patient monitoring due to potential side effects.
research Androgen Receptor Modulators: A Review of Recent Patents and Reports (2012-2018)
New androgen receptor modulators show promise for treating diseases like prostate cancer and muscle wasting.
research Baicalin Increases Hair Follicle Development by Enhancing Canonical Wnt/β-Catenin Signaling and Activating Dermal Papilla Cells in Mice
Baicalin helps hair growth by activating specific cell signals and pathways.
research Spironolactone and XPB: An Old Drug with a New Molecular Target
Spironolactone, a heart and liver drug, has new uses including cancer treatment, viral infection prevention, and skin condition improvement.
research Analytical Chemistry Studying Historical Pharmaceuticals and Health Care Formulations
Analytical chemistry helps understand the makeup and use of ancient medicines, but it's complex and challenging.
research Development and Validation of a Procedure for the Determination of Minoxidil in Hair-Regrowth Formulations Using Two Variants of Capillary Zone Electrophoresis
A method was created in 2005 to identify minoxidil, a hair growth ingredient, in products using two types of capillary zone electrophoresis, and it found that most products had about 2% minoxidil.
research A Lipid–Polymer Hybrid Nanoparticle-Loaded Dissolving Microneedle Patch for Promoting Hair Regrowth by Transdermal miR-218 Delivery
The microneedle patch effectively promotes hair regrowth by delivering miR-218.
research Effects of Ultraviolet Radiation on the Soluble Proteins of Human Hair
UV radiation increases protein loss from hair and reduces hair protein quality.
research Microscopical Characterization of Known Postmortem Root Bands Using Light and Scanning Electron Microscopy
The research found that postmortem root bands in hair are likely caused by the breakdown of a specific part of the hair's inner structure after death.