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Coumarin derivatives show promise as anti-estrogenic agents for treating breast cancer, with some in clinical trials.

Experts recommend using evidence-based methods to diagnose and treat hirsutism, focusing on symptoms and underlying causes.

Cushing's syndrome can cause serious health problems, and early treatment is crucial, but some issues may remain after treatment.

Anorexia and bulimia lead to serious health problems and increased risk of death, requiring aggressive treatment.

Childhood obesity is rising globally due to various factors, and early prevention and healthy lifestyle changes are crucial.

The conclusion is that using drugs to block the TOR pathway might slow aging and prevent age-related diseases.

Chemicals and body size might change when puberty starts and progresses, but more research is needed to confirm this.

The Endocrine Society advised against routine testosterone therapy for women, citing a need for more research on long-term safety and a clear definition of androgen deficiency.

Mutations in the SRD5A3 gene cause a new type of glycosylation disorder by blocking the production of a molecule necessary for protein glycosylation.

Teriflunomide helps reduce multiple sclerosis symptoms and is safe for most patients.

Hair loss and aging are caused by the breakdown of a key protein in hair stem cells.

Melanocyte stem cells in hair follicles are key for hair color and could help treat greying and pigment disorders.

AGA causes hair loss by shrinking hair follicles due to DHT binding, and can be treated with finasteride and minoxidil.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Testing basal 17-HP levels is a good way to screen for nonclassic adrenal hyperplasia in women with high androgen levels.

Pregnancy can cause various skin changes and diseases, with PUPPP being the most common skin condition specific to pregnancy.

Iron deficiency may be related to hair loss, but there's not enough evidence to recommend iron screening or supplements for all hair loss patients.

Artificial skin development has challenges, but new materials and understanding cell behavior could improve tissue repair. Also, certain growth factors and hydrogel technology show promise for advanced skin replacement therapies.

Visible light can damage skin and most sunscreens don't block it well; more research is needed on its effects and protection methods.

The document concludes that developing generic topical drugs requires ensuring they match the original in quality, composition, and structure, and often involves complex testing and regulatory steps.

Biotinidase deficiency has various symptoms and can be treated with biotin supplements.

Current treatments for alopecia show no significant long-term benefits.

Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.

The document concludes that recognizing and treating cutaneous lupus erythematosus early is crucial for managing the skin and potential systemic symptoms.

Androgens can cause hair growth in some areas and hair loss on the scalp.

Lichen planus is a skin condition that can resolve on its own, is linked to hepatitis C, and increases the risk of skin cancer.

Women with PCOS have heart-related issues not because of obesity, but due to insulin resistance and low adiponectin levels.

Guidelines for diagnosing common hair loss include detailed history, clinical examination, and various diagnostic techniques.

Congenital Adrenal Hyperplasia is a genetic disorder with two forms, causing symptoms like early puberty and severe acne, but can be identified through screening and treated with glucocorticoids.

Minoxidil works better for female hair loss, but cyproterone reduces scalp oiliness and causes menstrual issues.