20 citations
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January 2016 in “Intractable & Rare Diseases Research” In this clinical experience, treating frontal fibrosing alopecia with oral finasteride, hydroxychloroquine, tacrolimus, and excimer laser was associated with optimal results in patients with active inflammation.
5 citations
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November 2015 in “Journal of Enzyme Inhibition and Medicinal Chemistry” This study found that aliphatic ester moieties in 16-formyl-17-methoxy dehydroepiandrosterone derivatives increased their potency as 5α-reductase type 2 inhibitors in vitro compared to finasteride.
July 2024 in “Reactions Weekly”
1 citations
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December 2017 in “Research for Rural Development/Research for Rural Development (Online)” This study found no correlation between clinical signs and sex steroid levels in ferrets with hyperadrenocorticism and noted that androstenedione was elevated in many cases.
1 citations
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March 2016 in “Journal of The American Academy of Dermatology” This editorial response discusses the evidence for using 5-alpha reductase inhibitors in treating frontal fibrosing alopecia, acknowledging its potential benefits while emphasizing the need for further studies to establish it as a standard treatment.
23 citations
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October 2008 in “Journal of medicinal chemistry” This study suggests that PF-0998425 is an effective androgen receptor antagonist for sebum control and androgenetic alopecia with rapid metabolism reducing the risk of systemic side effects.
This study reported that prompt diagnosis and treatment with 5-alpha-reductase inhibitors and topical immunomodulators are key to mitigating the effects of frontal fibrosing alopecia and preventing permanent hair loss.
January 2023 in “Revista Brasileira de Parasitologia Veterinária/Brazilian Journal of Veterinary Parasitology” This study found that a single topical dose of fluralaner effectively eliminated Lynxacarus radovskyi mites from naturally infested domestic cats within 42 days, with treated cats remaining mite-free until day 98, unlike the untreated control group which continued to test positive.
16 citations
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January 2007 in “Actas dermo-sifiliográficas/Actas dermo-sifiliográficas” This review discusses frontal fibrosing alopecia and reports no clinical results; the authors note that no therapeutic options tested, including corticosteroids, finasteride, and minoxidil, have shown clear benefits.
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