72 citations,
April 2008 in “Organogenesis” Wnt signaling is crucial for skin and hair development and its disruption can cause skin tumors.
59 citations,
April 2016 in “Cell Reports” EdnrB signaling helps melanocyte stem cells regenerate and could be targeted to treat pigmentation issues.
55 citations,
December 2014 in “Dermatologica sinica/Zhōnghuá pífūkē yīxué zázhì” Keratinocytes control how melanocytes work.
54 citations,
November 2015 in “Methods in enzymology on CD-ROM/Methods in enzymology” Keratins are important for skin cell health and their problems can cause diseases.
50 citations,
December 2005 in “European Journal of Immunology” RXRα is crucial for proper immune response and links diet to immune function.
45 citations,
April 2016 in “Journal of Dermatological Science” The Wnt/β-catenin pathway can activate melanocyte stem cells and may help regenerate hair follicles.
45 citations,
May 2003 in “Journal of Cell Science” α3β1-integrin is crucial for maintaining normal hair follicle shape and function but not needed for the development of the surrounding skin.
43 citations,
September 2014 in “Molecular Plant” CLE40 and CRN/CLV2 pathways have opposite effects on root growth in Arabidopsis.
38 citations,
June 2016 in “Nanomedicine: Nanotechnology, Biology and Medicine” Peptide hydrogel scaffolds help grow new hair follicles using stem cells.
33 citations,
September 2017 in “Journal of clinical immunology” New treatments for immune disorders caused by FOXN1 deficiency are promising.
33 citations,
March 1994 in “PubMed” High ODC and low K1 and K10 may indicate early skin tumors in mice.
32 citations,
November 2016 in “Journal of Dental Research” Pannexin 3 is important for bone formation and the development of bone cells.
31 citations,
September 2013 in “Stem Cells” Smad1 and Smad5 are essential for hair follicle development and stem cell sleepiness.
29 citations,
March 2016 in “Cell cycle/Cell cycle (Georgetown, Tex. Online)” Isoproterenol helps hair follicle stem cells turn into beating heart muscle cells.
28 citations,
December 2016 in “Journal of Biomedical Materials Research Part A” Bone-forming cells grow well in 3D polymer scaffolds with 35 µm pores.
28 citations,
July 1993 in “The journal of investigative dermatology/Journal of investigative dermatology” Dermal papilla cells are crucial for hair growth and can induce new hair follicles.
27 citations,
September 2012 in “Dermatologic Clinics” The document concludes that using specific tools and tests is essential for identifying the cause of hair loss and deciding on the right treatment.
25 citations,
January 2000 in “Hormone Research in Paediatrics” Mutations in the androgen receptor gene cause Androgen Insensitivity Syndrome, affecting sexual development.
22 citations,
November 2012 in “Journal of cosmetic dermatology” Stem cells can rejuvenate skin, restore hair, and aid in wound healing.
22 citations,
August 1999 in “Mechanisms of Development” Pmg-1 and Pmg-2 are new genes important for skin and mammary gland development.
20 citations,
January 2013 in “Cell & Bioscience” Understanding how epigenetic regulation affects stem cells is key to cancer insights and new treatments.
11 citations,
February 2019 in “Stem cells international” Skin-derived stem cells grow faster and are easier to obtain than hair follicle stem cells, but both can become various cell types.
10 citations,
August 2020 in “Current protocols in stem cell biology” Scientists developed a way to create skin and hair cells from human stem cells, which could help treat burns and restore hair.
9 citations,
January 2015 in “Medical hypotheses” TCDD disrupts skin stem cells, causing skin issues like chloracne.
9 citations,
June 2008 in “Springer eBooks” Understanding hair follicle structure is key for treating hair disorders and could help develop new treatments.
9 citations,
April 2006 in “American Journal of Pathology” SGK3 is essential for proper hair growth and health.
8 citations,
May 2018 in “Primary Care: Clinics in Office Practice” Doctors should use a detailed patient history and physical exam to diagnose joint pain, and consult a rheumatologist early for suspected autoimmune diseases.
7 citations,
January 2009 in “Biological & pharmaceutical bulletin” Ferrous Ferric Chloride may improve skin cell function and increase hair growth in mice.
6 citations,
March 1999 in “Seminars in Cutaneous Medicine and Surgery” Scalp biopsies are essential for accurately diagnosing alopecia areata.
5 citations,
November 2021 in “The journal of investigative dermatology/Journal of investigative dermatology” Wnt/β-catenin signaling is important for keeping skin cell attachment structures stable.