17 citations,
December 2006 in “Gene Expression Patterns” Scube3 gene affects mouse embryo growth in multiple areas, but needs more research.
16 citations,
September 2018 in “Scientific reports” Scientists created keratinocyte cell lines from human hair that can differentiate similarly to normal skin cells, offering a new way to study skin biology and diseases.
16 citations,
August 1992 in “Archives of dermatological research” Lab-grown nail cells show characteristics similar to natural nail and hair.
13 citations,
December 2017 in “Stem cells” Low-dose radiation affects hair stem cell function and survival by changing their genetic material's structure.
13 citations,
December 1983 in “Canadian journal of zoology” Heterotypic cell contacts likely help hair matrix cells differentiate during mouse hair follicle development.
12 citations,
November 2020 in “Journal of Dermatological Science” Found microRNA differences in hair cells, suggesting potential treatment targets for hair loss.
10 citations,
November 2022 in “Protein & Cell” Quercetin significantly helps hair growth by activating hair follicles and improving blood vessel formation around them.
8 citations,
July 2014 in “General and Comparative Endocrinology” Finasteride affects frog testes by increasing testosterone, decreasing 5α-DHT, and impacting genes related to reproduction and other functions.
7 citations,
October 2015 in “Experimental dermatology” Blocking the mineralocorticoid receptor can help treat skin thinning caused by steroids.
6 citations,
October 2022 in “Journal of cell science” Keratin genes change gradually during skin cell development and should be used carefully as biomarkers.
6 citations,
August 2022 in “International Journal of Molecular Sciences” EDA signaling is linked to skin disorders, various cancers, and liver disease.
6 citations,
September 2020 in “Advanced Biology” Blue-light activation of TrkA improves hair-follicle stem cells' ability to become neurons and glial cells.
6 citations,
July 2007 in “Developmental Dynamics” The molecule Wise is involved in the development of various structures in chick embryos.
5 citations,
August 2021 in “Clinics in dermatology” PRP is popular in aesthetic treatments but its effectiveness and safety are still questioned.
5 citations,
July 2018 in “Experimental Dermatology” The "Punch Assay" can regenerate hair follicles efficiently in mice and has potential for human hair regeneration.
5 citations,
January 2017 in “Dermatologic Surgery” Storing hair follicle micrografts for longer times can cause them to enter a state similar to the natural hair shedding phase, which might impact hair transplant results.
4 citations,
November 2016 in “Dermatologic Therapy” Topical tretinoin may increase beard hair density.
4 citations,
January 2013 in “Advances in Experimental Medicine and Biology” Certain transcription factors are key in controlling skin stem cell behavior and could impact future treatments for skin repair and hair loss.
3 citations,
July 2023 in “Frontiers in Aging” Hair follicle stem cells change states with age, affecting hair growth and aging.
3 citations,
April 2022 in “Frontiers in Physiology” Ptch2 plays a key role in controlling stem cell function and the ability to regenerate after birth.
3 citations,
February 2022 in “Frontiers in cell and developmental biology” A specific RNA molecule, circCOL1A1, affects the growth and quality of goat hair by interacting with miR-149-5p and influencing cell growth pathways.
New treatments for hair loss, including a compound called "ALRV5XR", platelet-rich plasma, and Adult Stem Cell-based therapy, are showing promise, but more trials are needed for confirmation.
2 citations,
June 2022 in “Life” A 14-year-old boy is the youngest person reported with a rare, benign tumor related to hair follicles, usually found in older people.
2 citations,
June 2022 in “Cosmoderma” Regenerative medicine shows promise for improving hair and skin but needs more research for standard use.
2 citations,
November 2015 in “Actas Dermo-Sifiliográficas” Epidermal stem cells show promise for future dermatology treatments due to ongoing advancements.
2 citations,
September 2014 in “The American Journal of Cosmetic Surgery” Stem cells could potentially rebuild missing structures in wounds, improving facial skin replacement techniques.
1 citations,
January 2024 in “International journal of molecular sciences” The research identifies genes linked to wool quality in sheep and provides insights to improve wool production.
1 citations,
September 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” Skin organoids from stem cells can help study and treat skin issues but face some challenges.
1 citations,
April 2018 in “Journal of Investigative Dermatology” PRC1 is essential for proper skin development and stem cell formation by controlling gene activity.
1 citations,
October 1988 in “Clinics in dermatology” The document concludes that understanding how cells in the hair follicle grow and change is important for regulating hair growth.