5 citations
,
December 2016 in “International journal of biometeorology” In this study, bright light exposure during the daytime did not significantly affect clock gene expression in humans, although Rev-erb-ß expression appeared stronger under bright light compared to dim light.
6 citations
,
December 2017 in “Journal of Cosmetic and Laser Therapy” This study evaluated low-level laser therapy for treating Androgenic alopecia and suggested it may effectively stimulate hair growth and improve patient satisfaction, although more efficient treatments are needed.
January 2024 in “Journal of Clinical Images and Medical Case Reports” This article discusses frontal fibrosing alopecia as a type of Lichen planopilaris marked by gradual hair loss at the front of the scalp but reports no new clinical results.
293 citations
,
November 2011 in “Nature” This study found that the circadian clock regulates the activation state of murine epidermal stem cells, affecting tissue homeostasis and susceptibility to tumorigenesis when disrupted.
3 citations
,
October 2021 in “Kerala Journal of Psychiatry” Among breast cancer patients undergoing chemotherapy, this study found that anxiety and depression were present but did not affect overall quality of life.
July 2021 in “Archives of Aesthetic Plastic Surgery” In this study, combining endoscopic forehead lifting with hairline lowering successfully rejuvenated the upper facial area in 194 patients by lowering hairlines by an average of 18 mm and raising eyebrows by 5 mm, without serious complications.
February 2021 in “The Brown University Psychopharmacology Update” Finasteride use in young people may increase risk of suicidal thoughts and mental health issues.
32 citations
,
May 2012 in “PloS one” This study found that despite the persistence of aberrant double-negative T-cells, functional immune-competence was maintained after thymic transplantation in a patient with a rare FOXN1 mutation.
5 citations
,
March 2019 in “Facial Plastic Surgery Clinics of North America” In this article, the authors reviewed essential terminology and recommendations for creating a welcoming healthcare environment for transgender patients and providing gender-affirming therapy, emphasizing the unique health needs and disparities faced by this population.
June 2022 in “International Journal of Health Sciences (IJHS)” This review examines the role of certain proteins in the pathogenesis of polycystic ovary syndrome and reports no new results, emphasizing the potential for future diagnostic and therapeutic advancements.
111 citations
,
August 2002 in “Journal of Medicinal Chemistry” This study reports that 2-(1-Adamantyl)-4H-thiochromen-4-on-6-O-sulfamate is the most potent steroid sulfatase inhibitor identified so far, exhibiting 170-fold higher activity than the lead compound estrone sulfamate.
83 citations
,
January 2015 in “World Journal of Stem Cells” This review discusses current experimental approaches for regenerating human hair follicles using tissue engineering and isolated cells, but reports no successful strategies with adult cells yet found.
75 citations
,
January 2014 in “Korean Journal of Urology” This review discusses the adverse effects of 5α-reductase inhibitors, finasteride and dutasteride, on sexual, psychological, and vascular health, emphasizing the need for physicians to inform patients of these risks.
58 citations
,
December 2020 in “Mayo Clinic Proceedings” This paper discusses the variability in COVID-19 susceptibility and severity, emphasizing factors like biological differences and suggesting potential precision medicine approaches, but it reports no new clinical results.
39 citations
,
October 2014 in “Schweizerische medizinische Wochenschrift” This study found that while cyclophosphamide remains effective for severe autoimmune conditions, it is associated with gastrointestinal side effects, infections, some cases of irreversible amenorrhoea, and a higher risk of malignancies, emphasizing the need for long-term monitoring.
36 citations
,
June 2014 in “Experimental Neurology” This review outlines the main findings from clinical trials on teriflunomide's efficacy and safety for relapsing multiple sclerosis, noting clinical considerations and exploring its mechanisms based on various studies.
31 citations
,
February 2019 in “International Journal of Cosmetic Science” This study found that ultraviolet radiation negatively affects hair follicle functions in human scalp skin, and caffeine application may provide some protective effects against this damage.
28 citations
,
January 2021 in “Skin appendage disorders” This study observed that telogen effluvium, or acute hair loss, often occurs 1 to 3 months after SARS-CoV-2 infection, earlier than classic telogen effluvium.
28 citations
,
January 2012 in “Biological & pharmaceutical bulletin” This study found that the protein hairless acts as both a corepressor and coactivator of the vitamin D receptor, influencing gene transcription in a ligand-selective manner.
19 citations
,
January 2014 in “International Journal of Medical Sciences” The study suggests that abnormal activation of hair follicle stem cells and Wnt10b/β-catenin signaling may contribute to the development of sebaceous neoplasms.
18 citations
,
October 2020 in “PLoS ONE” This study highlights the interconnected emotional distress between patients with end-stage COPD and their family caregivers, emphasizing that both parties' functional and emotional variables influence each other's distress.
18 citations
,
March 2019 in “Journal of The European Academy of Dermatology and Venereology” This study found that finasteride use was not associated with sexual dysfunction in men with androgenetic alopecia, consistent with other large survey-based controlled studies.
16 citations
,
January 2020 in “Diabetes” In this study using diabetic rat models, the combination of AMD3100 and low-dose FK506 reduced wound healing time and improved microcirculation in diabetic foot ulcers, indicating a promising new systemic therapy.
13 citations
,
April 2019 in “American Journal of PharmTech Research” In this study, researchers highlighted that emulgels, a combination of emulsions and gels, offer a novel topical delivery method for hydrophobic drugs, possessing attributes such as easy spreadability and bio-friendliness, making them suitable for conditions like acne, fungal infections, and psoriasis.
12 citations
,
December 2023 in “Journal of Applied Pharmaceutical Sciences and Research” In this research, caffeine's versatile pharmacological actions were highlighted, demonstrating its stimulant, bronchodilator, diuretic, and potential anticancer effects through interactions with adenosine receptors, phosphodiesterase, and renal tubules, revealing valuable insights for drug development and therapeutic applications in medicine.
11 citations
,
March 2020 in “Immunology” This study reports that immunologically inert and skewed immune cell populations in developing human skin may contribute to wound healing and structural changes during skin development.
6 citations
,
April 2022 in “JMIR Dermatology” Public interest in COVID-19-related hair loss increased during COVID-19 surges, especially with the omicron variant.
4 citations
,
December 2023 in “Research Review” In this retrospective cohort study, researchers reported that 77% of 300 COVID-19 survivors experienced long COVID-19 symptoms such as fatigue and hair loss, with symptoms more likely in females, younger age groups, and hospitalized patients.
3 citations
,
September 2024 in “Journal of Pre-Clinical and Clinical Research” This study reviews the current understanding of psychiatric disorders in women with PCOS, finding links to the gut-brain axis, neurotransmitter and neuroendocrine dysfunction, and suggests the need for routine mental health screening in these patients.
3 citations
,
January 2023 in “Journal of Pharmaceutical Negative Results” This study reports that fluconazole emulgel formulations, using jojoba oil and liquid paraffin, showed effective drug release and improved characteristics for treating skin diseases compared to traditional oral formulations.