December 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that inducing miR-205 reduces actin contractility and stiffness in hair follicle stem cells and progenitors, stimulating hair regeneration in both young and old mice.
November 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that conditional deletion of Mof in mice resulted in severe defects in skin development, including compromised epidermal differentiation and hair growth, leading to perinatal lethality.
March 2021 in “Research Square (Research Square)” This study found that strontium ranelate may promote cartilage regeneration by enhancing chondrogenic differentiation and inhibiting the Wnt/β-catenin signaling pathway in rat models of cartilage defects.
November 2019 in “Harper's Textbook of Pediatric Dermatology” This review discusses potential causes of alopecia and hair overgrowth in pediatric patients, detailing diagnostic techniques and treatments, but presents no new research findings.
January 2012 in “Durham e-Theses (Durham University)” This study found that knock-down of keratin 15 in various cell lines affected cell spreading, morphology, migration, differentiation, and proliferation, suggesting its role in maintaining the stem cell nature of keratinocytes.
124 citations
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November 2000 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that human peptidylarginine deiminase type III is the predominant isoform in hair follicles and may modulate structural proteins during hair and hair follicle formation.
April 2015 in “Journal of Nutritional Therapeutics” This study found that a more liberal intake of restricted amino acids in patients with methylmalonic acidemia resulted in improved growth and fewer illness episodes.
14 citations
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May 2008 in “Journal of proteome research” This study found that dutasteride reduced β-amyloid plaque load in a cerebral amyloidosis model, seemingly linked to mitochondrial apoptosis and autophagy processes.
January 2011 in “Journal of Society of Cosmetic Chemists of Japan” This study found that a conditioner containing 18-MEA and SPDA can improve hair's smoothness and reduce flyaways, enhancing hair manageability.
March 2005 in “Journal of the American Academy of Dermatology” This study found that reintroducing certain depleted amino acids into weathered hair using cosmetic treatments can strengthen the hair, improving its look and feel and reducing damage and breakage.
47 citations
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March 2017 in “Materials Science and Engineering: C” In this study, decellularized human amniotic membrane was found to promote wound healing and reduce scar formation in rats with full-thickness skin defects, compared to traditional clinical treatments.
24 citations
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April 2016 in “Experimental Dermatology” This study found that chemical treatments like perming, dyeing, and bleaching significantly alter amino acids and lipids in human hair, which may impact hair strength and quality.
10 citations
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March 2014 in “Scandinavian journal of clinical and laboratory investigation” This study found that MDA-modified DNA may contribute to immune responses in alopecia areata patients by creating neo-epitopes, providing new insights into the condition's immunological mechanisms.
49 citations
,
May 1974 in “Biochimica et Biophysica Acta (BBA) - Protein Structure” Transamidases are present in the epidermis but their exact role is unclear.
18 citations
,
October 2022 in “JCI Insight” This study found that altered amino acid metabolism, specifically involving glutamic and aspartic acids, promotes neurovascular reactivity in rosacea, suggesting a potential metabolic target for treatment.
5 citations
,
August 2021 in “Frontiers in Cell and Developmental Biology” This study found that DHEA along with osteogenic induction medium significantly promotes the osteogenic differentiation and proliferation of human bone marrow mesenchymal stem cells from older individuals.
1 citations
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July 1997 in “The Lancet” This study suggests that a newly discovered protein, AMY117, found in Alzheimer's disease brain lesions may be crucial in the disease's development and progression.
75 citations
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June 2007 in “Journal of Biological Chemistry” This study found that the combination of MT-DADMe-ImmA and MTA selectively induced apoptosis in head and neck squamous cell carcinoma cell lines FaDu and Cal27, but not in normal fibroblasts or MTAP-deficient breast cancer cells.
April 2016 in “Journal of Investigative Dermatology” This study found that the peptide derivative beta-Ala-Pro-Dab-NHbenzyl may reduce wrinkles and sebum production in human skin by inhibiting dipeptidyl peptidase 4, suggesting potential for acne and skin inflammation treatment.
1 citations
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January 2009 in “Journal of S C C J” This study investigated the effect of peracetic acid treatment on hair fiber structure and found that disulfide bond oxidation altered thermal properties while preserving the α-crystal structure, suggesting different stabilizing interactions in hair fibers.
42 citations
,
May 1997 in “The Journal of Biochemistry” In this study, researchers purified and cloned rat peptidylarginine deiminase type III, demonstrating its activity and specific expression in the epidermis and hair follicles.
71 citations
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June 2005 in “Journal of Investigative Dermatology” This study demonstrates that PAD1 and PAD3 are involved in hair follicle differentiation, while PAD1 and PAD2 may play a role in the physiology of sweat glands and arrector pili muscles.
April 2024 in “Journal of environmental management” This study investigated the electron transfer processes in an iron-mediated DAMO–anammox system, finding that Fe3+ accelerated c-type cytochrome-mediated electron transfer and suggested that riboflavin acts as an electron shuttle and DIET may occur among these microorganisms.
October 2025 in “Coloration Technology” In this study, a new delipidisation method that removes over 97% of key lipids from wool rapidly and without yellowing was reported to improve wool processing and printing quality.
4 citations
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December 2018 in “Macedonian Journal of Chemistry and Chemical Engineering” This study developed a reliable RP-HPLC-DAD method, finding that amino acid concentrations in bleached hair decrease with higher hydrogen peroxide levels, notably affecting cystine.
September 2022 in “Research Square (Research Square)” This study found that caffeic acid treatment mitigated the negative effects of acrylamide toxicity in Wistar rats by normalizing tissue and serological indices.
3 citations
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January 2004 in “Sen i Gakkaishi” This study found that adding dithiodiglycolic acid to the hair straightening process decreased chemical damage and preserved the structural integrity of the hair matrix compared to using thioglycolic acid alone.
January 2024 in “International Journal of Cosmetic Science” This study found that 1,4-n-butylene dimaleate can restore the mechanical properties of reduced hair by reconnecting disulfide bonds and improving the hair's structural integrity using a thiol-Michael click reaction, compared to untreated reduced hair.
37 citations
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February 2005 in “Journal of Investigative Dermatology” This research suggests that defects in keratinocyte differentiation due to putrescine accumulation in SSAT transgenic mice lead to skin changes and hair loss, and reducing putrescine can promote hair regrowth.
August 2023 in “Dermatology reports” This case study of a 2-month-old boy with maple syrup urine disease highlights the dangers of restricting branched-chain amino acid intake, as it led to acrodermatitis dysmetabolica-like skin eruptions and hair loss, later resolved with careful dietary adjustments and monitoring.