research High-Content Drug Screening for Rare Diseases
High-content screening is useful for finding new treatments for rare diseases and has led to FDA-approved drugs.
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research Combined Oral Contraception and Bicalutamide in Polycystic Ovary Syndrome and Severe Hirsutism: A Double-Blind Randomized Controlled Trial
Birth control pills combined with bicalutamide are more effective at reducing excessive hair growth in women with PCOS than birth control pills alone.
research A Randomized Blinded Retrospective Study: The Combined Use of Micro-Needling Technique, Low-Level Laser Therapy, and Autologous Non-Activated Platelet-Rich Plasma Improves Hair Re-Growth in Patients with Androgenic Alopecia
Using micro-needling, low-level laser therapy, and platelet-rich plasma together significantly improves hair growth in people with hair loss.
research Morphometric-Stereological and Functional Epididymal Alterations and a Decrease in Fertility in Rats Treated with Finasteride and After a 30-Day Post-Treatment Recovery Period
Finasteride causes lasting fertility decrease in rats.
research PCOS in Lesbian and Heterosexual Women Treated with Artificial Donor Insemination
Sexual orientation does not affect the prevalence of PCOS or fertility rates in women undergoing artificial donor insemination.
research Cutaneous Manifestations in Biologically Treated Inflammatory Bowel Disease Patients: A Narrative Review
Biologic treatments for Crohn's disease and ulcerative colitis can cause skin problems, and doctors should adjust treatment if these occur.
research Progenitor-Cell-Enriched Micrografts as a Novel Option for the Management of Androgenetic Alopecia
Micrografts promote hair growth in androgenetic alopecia treatment.
research Adult Acne: Prevalence and Portrayal in Primary Healthcare Patients in the Greater Porto Area, Portugal
Many adults in Porto have acne, but few know or treat it.
research Technical Procedures for Preparation and Administration of Platelet-Rich Plasma and Related Products: A Scoping Review
The review found that the way Platelet-Rich Plasma is made varies a lot, which can change the results of medical treatments.
research Efficacy of an Agonist of α-MSH, the Palmitoyl Tetrapeptide-20, in Hair Pigmentation
Palmitoyl tetrapeptide-20 may help reduce hair greying and increase melanin production.
research Chemoprevention of Doxorubicin-Induced Alopecia in Mice by Dietary Administration of L-Cystine and Vitamin B6
L-cystine and vitamin B6 at high doses prevented hair loss in mice treated with a chemotherapy drug.
research The Hair Shaft: Normality, Abnormality, and Genetics
Hair microscopy is useful for diagnosing hair disorders, but clear definitions are needed for accurate genetic analysis.
research Modulation of Genomic and Postgenomic Alterations in Non-Cancer Diseases and Critical Periods of Life
N-acetyl-L-cysteine (NAC) can prevent DNA damage and protect cells from harm.
research The Hair Root Pattern After Calcipotriol Treatment For Scalp Psoriasis
Calcipotriol treatment for scalp psoriasis does not cause hair loss.
research The Diagnosis of Androgenetic Alopecia in Children: Considerations of Pathophysiological Plausibility
AGA in children needs careful diagnosis due to low androgen levels and possible other causes.
research The Role of Photobiomodulation When Associated with Microneedling in Female Pattern Hair Loss
Combining light therapy and microneedling shows promise for treating female hair loss.
research Effect of Finasteride on Ovulation Induction in Nonresponder (Hyperandrogenic) Polycystic Ovary Syndrome (PCOS) Women
Finasteride helps induce ovulation in nonresponder PCOS women.
research Integrin α3β1 in Hair Bulge Stem Cells Modulates CCN2 Expression and Promotes Skin Tumorigenesis
Removing integrin α3β1 from hair stem cells lowers skin tumor growth by affecting CCN2 protein levels.
research A 10 Mb Duplication in Chromosome Band 5q31.3–5q33.1 Associated with Late-Onset Lipodystrophy, Ichthyosis, Epilepsy, and Glomerulonephritis
A genetic duplication on chromosome 5 was linked to a woman's unique combination of medical conditions.
research Possible Role of 5-Alpha Reductase Inhibitors in Non-Invasive Bladder Urothelial Neoplasm: Multicentre Study
5-alpha reductase inhibitors may reduce bladder cancer recurrence and improve survival.
research Identification of Differentially Expressed Genes Affecting Hair and Cashmere Growth in the Laiwu Black Goat by Microarray
Specific genes influence hair and cashmere growth in Laiwu black goats.
research Expression of Type 1 5α-Reductase and Metabolism of Testosterone in Reconstructed Human Epidermis: A New Model for Screening Skin-Targeted Androgen Modulators
The study created a new method to test drugs that affect hormone processing in skin.
research Severe Impact of Late Diagnosis of Congenital Adrenal Hyperplasia on Gender Identity, Sexual Orientation, and Function: Case Report and Review of the Literature
Late diagnosis of congenital adrenal hyperplasia can greatly affect physical development, gender identity, and sexual health.
research An Urticarial Drug Eruption Caused by Tofacitinib for Alopecia Universalis
A patient with alopecia had hair regrowth with tofacitinib but developed a skin reaction, choosing to continue the treatment despite the side effect.
research Updates from the British Association of Dermatologists 91st Annual Meeting, 5-7 July 2011, London, UK
New treatments and management strategies for skin conditions like melanoma and Spitz naevi were discussed at the dermatologists' meeting.
research Follicular Bisection in Hair Restoration: In Vivo Experiment
Splitting one hair follicle into two can help regrow hair with a 50% to 70% success rate, useful when donor hair is limited.
research Optimizing Hyaluronic Acid: A Comprehensive Review of Rheological Insights for Clinical Practice
Understanding the properties of hyaluronic acid helps improve its use in facial aging treatments.
research The Profibrogenic Role of Neutrophil Extracellular Traps in Stenotic Crohn's Disease: A New Antifibrotic Target?
Targeting NETs may help reduce fibrosis in Crohn's disease.
research Mechanistic Synergy of Hair Growth Promotion by the Avicennia Marina Extract and Its Active Constituent Avicequinone C in Dermal Papilla Cells Isolated From Androgenic Alopecia Patients
Avicennia marina extract and avicequinone C can potentially promote hair growth and treat hair loss by interfering with hair loss mechanisms and boosting growth factors.
research Complications of Cushing's Syndrome: State of the Art
Cushing's syndrome can cause serious health problems, and early treatment is crucial, but some issues may remain after treatment.