research The Dynamic Duo: Niche and Stem Cell Interdependency
Stem cells and their surrounding environment in hair follicles work closely together, affecting hair growth and having implications for cancer and tissue regeneration.
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research The Suppression of Very Long Chain Fatty Acids Is Associated with Skin Carcinogenesis
Suppressing very long chain fatty acids is linked to skin cancer.
research Early Embryonic Exposure of Freshwater Gastropods to Pharmaceutical 5-Alpha-Reductase Inhibitors Results in a Surprising Open-Coiled 'Banana-Shaped' Shell
Certain drugs change freshwater snail shells to a "banana" shape.
research Expression Patterns of MITF During Human Cutaneous Embryogenesis: Evidence for Bulge Epithelial Expression and Persistence of Dermal Melanoblasts
Melanocyte precursors in human fetal skin follow a specific migration pattern and some remain in the skin's deeper layers.
research Expression of Beta-Catenin, p63, and CD34 in Hair Follicles During the Course of Androgenetic Alopecia
Higher p63 and CD34 levels found in specific scalp areas may affect hair loss progression.
research The Thrill of Scientific Discovery and Leadership with My Group
The author felt excited and honored to receive the 2016 Early Career Life Scientist Award.
research Cutaneous and Mucosal Lichen Planus: A Comprehensive Review of Clinical Subtypes, Risk Factors, Diagnosis, and Prognosis
Lichen Planus is a less common condition affecting skin and mucous membranes, with various types and associated risk factors, challenging to diagnose, significantly impacts life quality, and may have a risk of cancerous changes in oral lesions.
research Gene Expression in Rat Dermal Papilla Cells: Analysis of 2529 ESTs
Rat dermal papilla cells have unique genes crucial for hair growth.
research Cell-Type-Specific Chromatin States Differentially Prime Squamous Cell Carcinoma Tumor-Initiating Cells for Epithelial to Mesenchymal Transition
Different types of skin cells have unique genetic markers that affect how likely they are to spread cancer.
research Loss of TET2 Tips the Scales Toward Tumorigenesis
Loss of TET2 increases the risk of skin and oral cancer.
research Androgens and Androgen Receptor Action in Skin and Hair Follicles
Male hormones and their receptors play a key role in hair loss and skin health, with potential new treatments being explored.
research Epidermal Stem Cell Fate: What Can We Learn from Embryonic Stem Cells?
Embryonic and adult stem cells are valuable for improving skin grafts and cell therapy.
research Harnessing Mesenchymal Aggregation for Engineered Organ-Level Regeneration: Recent Progress and Perspective
Scientists are using clumps of special stem cells to improve organ repair.
research Second International Symposium: Epigenetic Regulation of Skin Regeneration and Aging
Epigenetic factors play a crucial role in skin health and disease.
research Clinical and Biological Impact of the Exposome on the Skin
Environmental factors, hormones, nutrition, and stress all significantly affect skin health and aging.
research Epithelial Wnt Ligand Secretion Is Required for Adult Hair Follicle Growth and Regeneration
Wnt ligands are crucial for hair growth and repair.
research Effect of Intense Pulsed Light Treatment on Human Skin In Vitro: Analysis of Immediate Effects on Dermal Papillae and Hair Follicle Stem Cells
Intense pulsed light treatment mainly damages pigmented hair parts but spares stem cells, allowing hair to regrow.
research Platelet-Derived Growth Factor Signaling Modulates Adult Hair Follicle Dermal Stem Cell Maintenance and Self-Renewal
PDGF signaling is crucial for maintaining and renewing hair follicle stem cells, which could help treat hair loss.
research TERT/BMI1-Transgenic Human Dermal Papilla Cells Enhance Murine Hair Follicle Formation In Vivo
Adding TERT and BMI1 to certain skin cells can improve their ability to create hair follicles in mice.
research Mitochondrial DNA Damage, Oxidative Stress, And Atherosclerosis
Improving mitochondrial health may better treat atherosclerosis than antioxidants.
research Cutaneous Signals of Immune System Disease
Skin issues can indicate immune system problems.
research A New Horizon in Facial Plastic Surgery: Skin Tissue Engineering and Stem Cell Therapy—Reality or Dream?
Stem cells could potentially rebuild missing structures in wounds, improving facial skin replacement techniques.
research The Direct Inhibitory Effect of Dutasteride or Finasteride on Androgen Receptor Activity Is Cell Line Specific
Dutasteride and finasteride affect different cell types differently.
research Secondary Cicatricial and Other Permanent Alopecias
The document says that treating the root cause of hair follicle damage is crucial to prevent permanent hair loss, and treatment options vary.
research The Dermal Papilla and Hair Follicle Regeneration: Engineering Strategies to Improve Dermal Papilla Inductivity
Improving dermal papilla cells can help regenerate hair follicles.
research Wound Healing Impairment in Type 2 Diabetes Model of Leptin-Deficient Mice: A Mechanistic Systematic Review
Leptin-deficient mice, used as a model for Type 2 Diabetes, have delayed wound healing due to impaired contraction and other dysfunctional cellular responses.
research Trends in the Global Organoid Technology and Industry: From Organogenesis in a Dish to the Commercialization of Organoids
Organoid technology is advancing and entering commercial use, with applications in disease modeling, drug development, and personalized medicine.
research JAK Inhibitors in Dermatology: The Promise of a New Drug Class
JAK inhibitors show promise for treating skin conditions like eczema, hair loss, and psoriasis.
research Alopecia Areata: A Comprehensive Review of Pathogenesis and Management
New treatments for Alopecia Areata show promise but need to be more effective and affordable.
research FOXN1 Deficiency: From the Discovery to Novel Therapeutic Approaches
New treatments for immune disorders caused by FOXN1 deficiency are promising.