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Modulating BMP activity changes the number, size, shape, and type of ectodermal organs.

Human hair follicle organ culture is a useful model for hair research with potential for studying hair biology and testing treatments.

Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.

Damage to skin releases dsRNA, which activates TLR3 and helps in skin and hair follicle regeneration.

Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.

TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.

New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.

Understanding how cells die in the skin is important for treating skin diseases and preventing hair loss.

Fibroblast growth factor receptor signaling controls cell development and repair, and its malfunction can cause disorders and cancer, but it also offers potential for targeted therapies.

The document concludes that while significant progress has been made in understanding skin biology and stem cells, more research is needed to fully understand their interactions with their environment.

The AUTS2 gene is linked to neurological disorders and may affect human brain development and cognition.

The research identified various cell types in mouse and human teeth, which could help in developing dental regenerative treatments.

The research found that Atypical Progeroid Syndrome has unique symptoms and is not caused by the buildup of a certain mutant protein.

Men, especially older ones with health issues like prostate cancer, may have worse COVID-19 outcomes and could benefit from therapies targeting male hormones.

Wnt and Notch signaling help wound healing by promoting cell growth and regulating cell differentiation.

Applying a special compound can promote hair growth without harmful side effects.

KGF and activin are crucial for skin healing and repair.

Hair, teeth, and mammary glands develop similarly at first but use different genes later.

Skin's Regulatory T cells are crucial for maintaining skin health and could be targeted to treat immune-related skin diseases and cancer.

New single-cell analysis techniques are improving our understanding of stem cells and could help in treating diseases.

Survivors of Stevens-Johnson syndrome/toxic epidermal necrolysis need ongoing care for various long-term health problems.

Recombinant cytokine therapy can cause skin reactions ranging from mild to severe.

The document concludes that the hair cycle is a complex process involving growth, regression, and rest phases, regulated by various molecular signals.

Both genes and environmental factors like chemicals may contribute to the increase in hypospadias, but the exact causes are still unclear.

Restoring hair bulb immune privilege is crucial for managing alopecia areata.

Fullerenes show potential in skin care but need more safety research.

Scientists turned mouse stem cells into skin cells that can grow into skin layers and structures.

Scientists created stem cells that can grow hair and skin.

Hair follicles are hormone-sensitive and involved in growth and other functions, with potential for new treatments, but more research is needed.

A genetic change in the EDAR gene causes the unique hair traits found in East Asians.