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The timing of when the gene Bmal1 is active affects aging and survival, with its absence during development, not adulthood, leading to premature aging.

Stem cells are crucial for skin repair and new treatments for chronic wounds.

Two main types of fibroblasts with unique functions and additional subtypes were identified in human skin.

Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.

Biomaterials with MSC-derived substances could improve tissue repair and have advantages over direct cell therapy.

The Rotterdam Study aims to understand various diseases in older adults.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Mice lacking the PPARγ gene in their fat cells had almost no fat tissue, severe metabolic problems, and abnormal development of other fat-related tissues.

About 7% to 15% of Iranian women have polycystic ovary syndrome, depending on the criteria used to diagnose it.

Tiny pollution particles called PM2.5 can harm skin cells by causing stress, damage to cell parts, and cell death.

The skin is a complex barrier for drug penetration, but understanding its structure and interactions can improve drug delivery methods.

More dermal papilla cells in hair follicles lead to larger, healthier hair, while fewer cells cause hair thinning and loss.

PrEP for HIV is less effective in transgender women mainly due to low adherence to the treatment.

Interferon alfa-2a is effective for treating cutaneous T cell lymphoma but has significant side effects.

Pregnancy can cause various skin changes and diseases, with PUPPP being the most common skin condition specific to pregnancy.

Skin needs dermal β-catenin activity for hair growth and skin cell multiplication.

Iron deficiency may be related to hair loss, but there's not enough evidence to recommend iron screening or supplements for all hair loss patients.

Male and female skin differ in many ways, which could lead to gender-specific skin treatments.

The cuneate nucleus has two main neuron types: relay neurons and interneurons.

Male and female bodies respond differently to stress, influenced by hormones and development stages, with implications for stress-related diseases.

Most women with excess hair growth have an underlying hormonal issue, often treated with medication and hair removal methods.

Regulatory T-cells are important for healing and regenerating tissues in various organs by controlling immune responses and aiding stem cells.

Finasteride treats enlarged prostate and may help with baldness, but effects on sexual function and male fetuses are unclear.

Skin cells produce and activate vitamin D, which regulates skin functions and supports hair growth.

Essential oils in cosmetics can offer benefits but may cause allergies and should be used carefully.

Spironolactone is a safe and effective treatment for reducing excessive hair growth in women.

Hair follicles significantly increase the speed and amount of caffeine absorbed through the skin.

The 2003 guidelines suggest that while some treatments can regrow hair in alopecia areata, none alter the disease's progression, and wigs may be the best option for extensive hair loss.

Androgens can help prevent memory problems caused by apoE4.

Hair loss affects self-esteem and quality of life; treatments can help.