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The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

About 7% to 15% of Iranian women have polycystic ovary syndrome, depending on the criteria used to diagnose it.

Minoxidil and finasteride treat hair loss in men, while minoxidil treats hair loss in women.

MK-0773 safely increased muscle mass but did not improve muscle strength or function in elderly women with sarcopenia.

Hair color production in mice is closely linked to the hair growth phase and may also influence hair growth itself.

Artificial skin development has challenges, but new materials and understanding cell behavior could improve tissue repair. Also, certain growth factors and hydrogel technology show promise for advanced skin replacement therapies.

Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

Use minoxidil for hair loss; finasteride and dutasteride for men, dutasteride for women.

WNT10A mutations often cause ectodermal dysplasias, with males showing more tooth issues than females.

Genetic variation in the androgen receptor gene mainly causes early-onset hair loss, with maternal inheritance playing a key role.

Fungi-produced compounds can change plant root growth.

Different animals have unique versions of the enzyme that changes testosterone into another hormone, which is important for creating effective treatments for prostate and hair loss conditions.

Women with PCOS are more likely to have impaired glucose tolerance and type 2 diabetes, especially if they are Asian or obese.

Regulatory T-cells are important for healing and regenerating tissues in various organs by controlling immune responses and aiding stem cells.

Shorter CAG repeats may cause hair and skin issues, while longer ones may link to acne.

Men are more likely to have severe COVID-19 cases and fatalities than women due to factors like lifestyle, aging, and biological differences.

Melatonin may benefit skin health and could be a promising treatment in dermatology.

The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.

Hair loss affects self-esteem and quality of life; treatments can help.

Cancer treatments targeting specific cells and the immune system can cause skin, mouth, hair, and nail problems, affecting patients' quality of life and treatment adherence.

Minoxidil, finasteride, and low-level laser light therapy effectively treat hair loss.

Jumonji genes are important for development and their mutations can cause abnormalities, especially in the heart and brain.

Bone Morphogenetic Proteins (BMPs) help control skin health, hair growth, and color, and could potentially be used to treat skin and hair disorders.

Hormone treatments in transsexual individuals reduce hair growth and oil production in male-to-females and increase them in female-to-males.

Isotretinoin is highly effective in treating severe acne, rosacea, and gram-negative folliculitis.

The document concludes that the exact way alcohol causes harm to fetal development is unknown, but it significantly affects nutrient transport to the fetus and a safe level of alcohol during pregnancy is not determined.

Some medicinal plants can help heal wounds and may lead to new treatments.

Pectin biosynthesis is essential for the growth of cotton fibers and Arabidopsis root hairs.

Hormone treatments for transgender individuals generally improve mental health and physical transition, with some health risks that require medical supervision.

Scientists found a new, less invasive way to study body clocks using hair cells, which shows shift workers' body clocks don't match their lifestyles.